Hub : Genes

FZD2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.3440	0.0960	0.0023	0.006	NA	-0.002	NA	-0.010	2.1e-01	NA	3.6e-01	NA	8.9e-01
2	GTEx	Breast Mammary Tissue	0.3510	0.1460	0.0010	0.006	NA	0.024	NA	0.014	1.5e-01	NA	2.2e-02	NA	5.9e-02
3	GTEx	Breast Mammary Tissue (Female)	0.1006	0.1302	0.2100	0.081	NA	0.019	NA	0.053	2.1e-03	NA	9.0e-02	NA	1.1e-02
4	GTEx	Cells Transformed fibroblasts	0.1110	0.0470	0.0025	0.001	NA	0.036	NA	0.007	2.7e-01	NA	1.0e-03	NA	9.7e-02
5	METSIM	Adipose	0.0822	0.0361	0.0015	0.007	0.023	0.003	0.027	0.008	2.7e-02	2.0e-04	1.0e-01	4.8e-05	1.8e-02
6	YFS	Blood	0.1454	0.0264	0.0000	0.125	0.123	0.122	0.127	0.120	1.1e-38	4.8e-38	9.8e-38	1.8e-39	5.1e-37
7	TCGA	Esophageal Carcinoma	0.2370	0.1010	0.0048	0.107	0.079	0.121	NA	0.132	2.8e-04	1.7e-03	1.1e-04	NA	5.5e-05
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0468	0.0251	0.0090	0.013	0.008	0.026	NA	0.026	1.1e-02	3.9e-02	5.7e-04	NA	5.9e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.5	0.8	2.5	-0.4	1.5	-1.6	0.4	1.1	-0.4	-0.3	0.0
Bipolar Disorder or Schizophrenia	1.1	2.6	9.4	-1.1	1.4	-3.1	1.2	0.1	-2.3	0.1	1.1
Depressed Affect (Nagel 2018)	0.9	1.8	4.5	0.4	2.1	1.1	-1.2	2.1	1.1	1.4	0.2
Depression (Nagel 2018)	0.9	1.3	8.4	-0.4	0.9	0.6	-0.2	2.9	0.9	0.5	0.1
Intelligence (Savage-Jansen 2018)	0.7	2.1	7.3	-1.0	-2.2	-0.2	1.0	-1.6	-0.5	-2.7	0.7
Neuroticism (Nagel 2018)	1.0	2.4	7.2	0.4	2.7	0.3	-1.6	2.1	0.5	2.2	-0.3
Schizophrenia (2018)	1.2	2.5	7.2	-1.1	0.6	-2.7	1.3	-0.7	-2.7	0.4	1.4
Schizophrenia vs Biploar Disorder	1.4	1.8	2.5	-1.2	-1.5	-1.6	-1.1	-1.5	-1.5	1.1	-1.0
Worry (Nagel 2018)	0.7	1.5	3.2	-1.2	1.8	-0.9	-0.7	1.5	-0.8	1.7	0.3
Alzheimer’s Disease (in mother)	0.5	0.6	2.0	-0.8	0.5	0.1	1.4	-1.1	-0.6	-0.3	-0.0
Alzheimer’s Disease (in father)	1.0	1.1	3.3	0.9	-0.7	0.7	-0.9	-0.7	0.6	1.3	-1.8
Alzheimer’s Disease (including proxy)	0.5	0.8	2.3	0.3	0.2	1.0	0.6	-1.5	0.6	0.3	-1.5
Crohns Disease (2017)	0.6	1.3	5.1	0.9	-2.3	-0.4	-0.7	-1.8	-0.8	0.0	0.5
Irritable Bowel Disease (IBD)	0.5	1.2	4.2	-0.1	-1.5	-0.2	0.5	-2.0	-0.7	-0.8	1.3
Ulcerative Colitis (UC)	0.6	1.1	2.9	-1.5	-0.3	-0.3	1.2	-1.7	-0.7	-0.7	1.1
Major Depression (MDD)	0.8	1.0	3.2	0.1	0.9	-0.3	1.8	0.9	0.1	1.0	-1.3
Reaction Time	0.2	0.4	0.8	0.5	-0.1	-0.9	-0.7	0.7	-0.2	-0.7	0.9
Verbal and Numeric Reasoning (VNR)	0.8	2.0	5.3	-2.0	-1.8	0.4	0.3	-1.4	-0.1	-2.3	0.8
Breast Cancer	0.4	1.0	5.3	-2.3	0.9	-0.9	-0.1	-0.7	-0.9	0.2	0.1
Ovarian Cancer	1.5	2.0	5.3	1.9	-0.7	1.9	0.3	0.6	2.3	1.0	-1.2
Prostate Cancer	0.7	1.0	2.1	-1.4	-0.6	-1.0	-0.9	-1.2	-1.0	0.4	-1.3
Age at First Birth	0.3	0.4	1.5	-0.2	-1.2	-0.8	0.3	-0.5	-0.6	0.2	-0.1
Bipolar Disorder (2011)	0.4	0.4	1.1	-0.7	0.8	-1.0	0.4	0.9	-0.6	0.0	0.0
Body Mass Index (BMI) (2010)	0.6	0.8	3.2	-1.1	0.1	-0.3	-0.0	0.4	0.0	1.8	-1.5
Coronary Artery Disease (CAD)	0.6	0.7	1.7	1.3	-1.1	0.9	-0.8	0.5	0.7	-0.9	0.2
Crohns Disease (2012)	1.3	2.2	7.6	0.8	-2.8	-1.1	-0.8	-1.9	-1.7	0.2	0.9
Mean Putamen Volume	0.9	1.0	3.3	-1.8	-0.9	-0.1	-0.5	1.0	-0.1	-1.1	1.2
Fasting Glucose	0.9	1.1	5.8	-0.8	0.8	-0.6	0.6	-0.4	-0.8	-0.1	2.4
HbA1C	0.2	0.3	1.0	-0.5	-0.2	-0.4	-0.2	1.0	-0.0	0.7	-0.4
HDL Cholesterol	1.7	2.8	5.6	0.6	-0.2	1.9	1.5	2.3	2.4	-2.0	1.0
LDL Cholesterol	1.4	2.3	10.1	0.4	0.3	-1.1	-3.2	1.4	-0.5	2.1	-0.5
Lupus	1.1	1.6	5.7	1.6	-0.3	2.4	0.2	-0.7	1.6	-0.9	0.8
Neuroticism (2016)	1.0	1.4	3.8	-1.1	1.8	0.1	-0.5	0.4	-0.3	1.9	-1.6
Primary Biliary Cirrhosis	0.4	0.6	1.3	-0.1	-0.7	-0.9	0.5	-1.1	-1.0	0.8	0.4
Rheumatoid Arthritis	0.9	1.2	5.1	1.1	2.3	1.1	1.0	0.4	0.9	-0.3	0.4
Schizophrenia (2014)	0.7	1.6	5.6	-0.7	0.5	-2.4	1.0	0.3	-2.0	0.3	1.2
Triglycerides	1.2	1.9	9.8	-0.4	0.4	-1.2	-1.0	-0.3	-1.6	3.1	-0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.5	0.4	0.3	-1.9	0.3	-0.7	-1.4	0.0	-0.0
Ulcerative Colitis	0.4	0.6	1.7	-0.7	-1.0	0.1	0.4	-1.3	-0.4	0.9	-0.6
Blood Eosinophil Count	0.1	1.1	3.7	-0.1	-0.9	0.8	-1.1	-1.2	-0.2	-0.8	1.9
Blood Platelet Count	3.9	44.8	123.2	-1.9	11.1	-1.1	5.4	9.8	1.7	-4.0	9.3
Blood Red Count	0.3	2.6	7.8	-1.9	-1.4	0.2	-2.8	2.6	0.8	0.7	0.2
Blood White Count	0.2	1.7	6.3	-1.2	2.5	-1.2	0.1	-0.6	-1.5	0.7	1.2
Heel T-Score	5.8	46.2	201.6	-4.1	10.4	1.4	14.2	1.1	2.5	-4.5	3.7
BMI	0.6	3.4	11.3	-1.7	3.4	0.0	3.0	-1.0	-0.2	0.8	-1.4
Height	3.2	62.5	130.0	4.8	3.0	11.4	9.9	0.4	10.3	-10.0	5.9
Waist Hip Ratio (WHR)	1.0	4.3	18.1	-1.3	4.3	-2.1	1.5	1.1	-2.0	1.5	0.7
Systolic Blood Pressure	2.4	12.0	36.6	-6.0	2.1	-4.7	1.7	0.4	-4.4	-0.3	3.2
Smoking Status	0.9	2.1	3.2	-0.7	-1.5	-1.1	-1.8	-1.8	-1.0	1.7	-1.5
Allergy or Eczema	0.2	0.5	3.1	-0.3	1.8	0.3	0.2	0.8	-0.3	0.0	0.4
Cardiovascular Disease	0.8	2.5	7.0	-1.0	2.6	-0.9	1.7	1.8	-0.8	-1.2	1.8
Hypothyroidism (self reported)	0.6	1.4	5.9	-0.2	-2.1	-0.2	-2.4	-0.1	-0.4	-0.3	-0.8
Respiratory disease	1.4	3.0	11.0	-1.4	3.3	0.2	1.5	1.2	-0.1	2.4	-1.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.3	-0.2	1.1	0.5	0.2	1.1	0.5	-1.5	0.7
Lung FEV1/FVC ratio	0.3	1.4	3.2	-1.5	-0.7	-1.6	-0.8	-0.8	-1.0	-1.8	0.5
Lung FVC	1.3	6.7	29.2	0.4	1.0	2.6	5.4	-2.5	1.6	-2.5	1.2
Neuroticism	0.9	2.2	5.7	0.2	2.4	0.4	-1.2	2.3	0.2	2.3	-0.0
Chronotype (morning person)	0.9	2.2	7.4	1.3	0.4	2.0	2.7	0.6	0.9	-0.5	1.7
Hair Pigment	0.1	3.2	6.7	2.5	-0.5	-0.3	-0.0	-2.5	-0.3	2.6	-2.4
Tanning	0.1	0.9	2.1	0.8	0.3	1.3	1.2	-0.1	1.4	-1.1	0.2
Hand grip strength (left)	4.2	11.0	33.0	0.9	0.7	4.7	5.7	-2.2	3.1	-3.3	2.6
Number of treatments/medications taken	0.4	0.8	2.6	-0.4	0.3	-0.3	1.6	0.6	-0.5	0.3	1.6
Average weekly spirits intake	0.5	0.6	1.6	-1.3	0.1	-0.6	0.2	-1.1	-1.1	0.8	-0.0
Sensitivity / hurt feelings	1.8	3.1	10.5	0.6	2.2	-1.0	-1.6	-0.6	-1.0	3.2	-1.9
Frequency of depressed mood in last 2 weeks	1.7	2.4	14.9	-0.1	0.6	0.7	-1.2	3.9	1.4	0.5	-0.5
Hearing difficulty/problems: Yes	0.2	0.3	0.6	-0.5	-0.7	-0.5	0.8	-0.3	-0.6	-0.2	0.3
Relative age of first facial hair	1.9	4.0	7.0	-1.6	-0.2	-2.0	-2.4	-0.3	-2.4	2.6	-2.5
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.5	-1.0	-1.4	-0.1	-1.5	1.6	-0.1	0.3	0.5
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.4	-0.5	2.1	-0.2	-0.0	0.5	-0.7	1.8	-0.7
Ever had hysterectomy (womb removed)	0.8	0.9	4.2	0.7	1.0	0.2	2.1	0.1	0.0	0.4	0.9
Systolic blood pressure, automated reading	1.4	4.1	7.7	-2.6	2.5	-2.8	1.4	0.3	-2.8	0.7	1.4
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.6	-0.8	-0.8	-1.4	-1.9	0.6	-0.6	0.7	0.2
Angina	0.9	1.1	4.1	-0.5	-0.5	-1.9	-0.6	-0.4	-2.0	0.7	0.0
Medication for hormone replacement therapy	1.6	1.8	5.5	-2.3	0.7	-1.7	0.8	-0.4	-1.7	1.4	0.0
Vitamin and mineral supplements	2.0	2.7	12.2	1.6	-3.5	0.6	-1.1	-2.0	0.2	-0.9	-0.5
Supplements: Zinc	0.7	0.7	3.2	-0.6	0.8	-1.1	-0.3	1.8	-0.5	0.3	0.4
Medication: Co-codamol	2.7	3.1	7.5	-1.2	1.8	-1.7	0.5	0.8	-1.9	2.4	-2.7
Medication: Metformin	0.2	0.3	1.0	-0.2	0.3	0.7	0.1	0.3	0.4	-0.9	1.0
Diabetes (father)	1.2	1.4	5.4	-2.3	-0.9	-1.6	-0.3	-0.9	-1.0	-0.9	0.1
Diabetes (mother)	0.4	0.5	1.8	-0.9	-0.3	-0.5	0.5	1.3	-0.3	-0.0	0.7
Severe depression (siblings)	1.4	1.6	3.5	-0.7	0.3	-1.2	-1.3	0.9	-1.3	1.7	-1.9
Pack years adult smoking proportion	0.2	0.3	0.5	0.6	0.5	0.6	-0.7	0.1	0.7	0.4	-0.2
Impedance of leg (right)	0.9	4.3	14.8	-1.5	-0.4	-3.8	-0.2	1.3	-3.1	0.8	2.4
Leg fat-free mass (left)	2.3	12.2	29.1	1.3	2.8	5.4	4.8	0.0	4.9	-3.5	0.4
Trunk fat percentage	1.7	7.0	31.3	-1.7	4.5	-0.6	5.6	0.8	-0.5	0.3	0.2
Hand grip strength (right)	3.5	9.6	29.0	0.2	1.5	4.2	5.4	-1.3	3.1	-3.1	2.5
Townsend deprivation index at recruitment	1.9	2.6	13.2	-0.9	0.3	-1.9	-3.6	-0.8	-1.6	0.2	-0.4
Current tobacco smoking	1.3	2.2	5.4	-0.2	-1.5	-1.0	-2.1	-1.0	-1.4	2.3	-1.3
Average weekly fortified wine intake	0.8	0.9	1.9	1.4	1.1	-0.5	0.7	0.9	-0.4	1.3	-1.0
Maternal smoking around birth	0.3	0.4	1.3	-0.2	-0.6	-0.8	-1.2	-0.3	-0.6	-0.6	-0.4
Fed-up feelings	0.8	1.5	5.2	0.1	2.1	0.7	-0.5	1.1	0.1	2.3	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.3	-0.5	1.2	0.7	0.6	1.8	0.4	0.2	0.5
Relative age voice broke	2.7	4.1	8.2	-2.4	0.0	-1.7	-1.7	-1.6	-2.9	2.8	-1.7
Taking other prescription medications	0.5	0.8	3.4	-0.6	-0.0	-0.9	0.4	-0.8	-1.9	0.9	0.7
Age when periods started (menarche)	2.7	6.4	16.2	2.6	-2.1	0.6	-4.0	3.1	1.4	2.2	-2.7
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	5.4	-0.1	2.3	0.6	1.6	1.2	0.5	-0.3	0.9
Heel bone mineral density (BMD) T-score, automated (left)	3.9	8.9	30.8	-2.7	5.3	0.2	5.6	0.3	0.7	-1.4	1.8
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.9	-0.3	0.8	-0.4	0.5	0.4	0.0	-1.7	1.6
Qualifications: CSEs or equivalent	0.7	0.9	3.8	-0.0	1.9	-0.1	0.5	0.9	-0.4	1.3	-0.1
Serious illness, injury or assault to yourself	1.4	1.7	4.0	-0.3	-2.0	0.4	-0.8	2.0	0.4	1.7	-1.3
High blood pressure	0.4	1.1	2.3	1.1	1.1	-0.6	0.9	0.4	-0.8	-1.5	1.5
Hayfever, allergic rhinitis or eczema	0.5	1.1	5.1	-0.9	2.2	-0.2	1.4	0.4	-0.7	0.4	-0.4
Multivitamins +/- minerals	1.0	1.3	6.0	-0.7	2.4	0.0	1.4	1.2	0.3	0.2	-0.3
Stomach or abdominal pain in last month	1.0	1.2	2.3	-0.9	1.5	-1.0	0.7	-0.9	-1.3	1.4	0.8
Supplements: Glucosamine	3.4	4.4	10.2	-3.2	3.0	-1.2	2.6	-0.5	-1.7	1.3	-1.8
Diverticular disease/diverticulitis (self-reported)	3.2	3.8	22.7	-0.2	1.2	0.7	4.8	0.6	0.3	-1.6	1.7
Medication: Atenolol	0.6	0.7	2.3	0.0	-0.1	-1.3	-0.2	-1.0	-1.5	-0.4	1.0
Medication: Levothyroxine sodium	1.2	2.0	7.8	-0.8	-1.9	-1.1	-2.8	-1.0	-1.5	0.3	-0.3
Sitting height	4.0	28.4	55.2	2.3	-1.6	7.1	5.7	-0.3	6.8	-7.4	6.0
Chronic bronchitis/emphysema (father)	2.1	2.5	7.7	0.4	0.2	2.0	1.0	2.8	2.5	-0.3	0.7
High blood pressure (mother)	0.4	0.5	1.4	0.2	-0.3	-1.1	-0.5	1.2	-0.9	-0.2	0.4
Body mass index (BMI)	0.5	2.2	9.7	-0.7	3.1	0.0	2.5	0.1	-0.0	0.5	-1.1
Impedance of leg (left)	1.1	5.2	17.7	-1.9	-0.7	-4.2	-0.2	0.9	-3.5	1.0	2.2
Leg predicted mass (left)	2.4	12.5	29.7	1.4	2.9	5.5	4.9	0.1	4.9	-3.5	0.3
Trunk fat mass	1.7	7.5	35.8	-1.1	4.4	1.2	6.0	0.5	1.1	-0.9	0.4
Waist circumference	1.0	3.8	15.1	0.0	3.9	0.8	3.6	1.0	0.8	-0.1	-0.0
Number of incorrect matches in round	1.1	1.9	5.7	-0.4	1.7	-0.7	-2.0	0.5	-1.0	2.4	-0.3
Past tobacco smoking	0.8	1.4	4.7	0.8	1.3	0.7	1.4	2.2	0.6	-0.3	1.1
Alcohol usually taken with meals	0.9	1.5	3.8	0.0	-0.2	0.4	1.9	-0.5	0.8	-1.9	1.8
Nervous feelings	1.0	1.9	5.8	-1.3	1.9	-1.0	0.1	0.5	-1.0	2.4	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	5.2	-1.0	2.3	0.7	-0.8	2.3	0.5	1.3	-0.5
Hearing difficulty/problems with background noise	1.2	1.9	8.6	-1.1	0.3	-1.0	-0.4	0.6	-0.8	2.9	-1.6
Hair/balding pattern: Pattern 2	1.1	1.4	3.0	0.9	-1.4	-0.6	-1.7	0.4	-0.4	1.7	-1.2
Had menopause	1.1	1.3	3.2	1.4	-0.5	1.8	-1.0	1.0	1.7	-0.2	0.8
Had other major operations	1.0	1.2	3.5	0.9	0.2	1.9	0.9	1.3	1.4	-1.0	0.0
Forced vital capacity (FVC)	3.1	12.0	38.9	-0.2	1.7	4.0	6.2	-0.9	3.5	-4.0	3.1
Heel bone mineral density (BMD) T-score, automated (right)	3.1	7.1	22.8	-3.5	4.5	-0.5	4.8	0.2	-0.0	-0.6	1.2
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	7.8	-2.8	-0.1	-0.8	-1.2	1.6	0.1	0.8	0.4
Qualifications: None of the above	0.5	1.1	2.8	0.4	0.9	1.5	0.2	0.7	0.8	1.7	-1.4
Financial difficulties in last 2 years	0.5	0.6	2.1	0.3	0.3	1.1	-0.1	-0.7	0.6	-1.5	0.8
Mouth/teeth dental problems	0.7	1.1	2.1	-1.0	-0.5	-1.4	-0.9	-0.8	-1.5	0.1	-1.2
Heart attack	0.5	0.6	1.7	0.4	-1.2	-0.2	-0.9	0.7	-0.4	-0.3	1.3
Allergy	0.9	2.0	7.7	1.6	-2.8	0.0	-1.8	-0.7	0.6	-0.7	0.8
Pain all over the body in last month	0.9	1.0	3.4	-0.3	-0.0	-0.5	-1.4	1.8	0.1	0.8	-1.1
Diabetes (self-reported)	0.2	0.3	1.6	-0.5	0.1	0.4	0.1	-0.1	0.2	-1.3	0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	1.4	-0.9	-1.2	-0.4	-0.2	-0.0	-0.4	0.6	-0.8
Medication: Ramipril	0.7	0.9	1.7	1.1	-1.3	-0.8	0.8	0.8	-0.5	-0.6	1.3
Medication: Simvastatin	0.4	0.6	1.6	-0.1	-0.5	-1.2	-1.1	-0.3	-1.3	-0.5	-0.1
Fluid intelligence score	0.6	1.2	2.6	-1.6	-1.4	-0.2	0.1	-1.1	-0.6	-1.6	1.1
Illnesses of siblings	0.3	0.4	1.0	-0.2	0.5	0.7	-0.6	-1.0	0.7	-0.6	-0.4
Neuroticism score	0.8	1.7	5.0	-0.2	2.2	-0.3	-0.8	1.9	-0.2	2.0	-0.1
Weight	1.8	9.0	29.4	0.2	3.6	3.4	5.4	0.4	3.1	-2.7	1.0
Impedance of arm (right)	0.6	2.7	7.6	-1.6	1.4	-1.4	2.8	0.7	-1.2	-1.1	2.2
Arm fat percentage (right)	1.3	5.0	19.1	-1.6	4.2	-0.4	4.4	0.6	-0.2	-0.2	-0.4
Trunk fat-free mass	2.2	12.6	34.9	2.2	0.4	5.9	3.5	-0.6	5.4	-4.4	0.7
Hip circumference	1.1	4.9	14.0	0.7	2.4	2.5	3.7	1.4	2.8	-1.6	-0.0
Time employed in main current job	0.3	0.3	0.5	0.4	0.4	0.6	0.7	0.6	0.7	-0.4	0.7
Alcohol intake versus 10 years previously	0.2	0.3	1.1	-0.2	0.9	0.0	0.4	1.0	0.2	0.2	0.5
Father’s age at death	0.2	0.3	0.7	-0.5	0.2	0.3	0.2	0.7	0.8	-0.8	-0.0
Worrier / anxious feelings	1.2	2.3	7.8	0.2	1.6	-1.6	-0.0	1.6	-1.5	2.8	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	4.6	-1.2	0.0	-0.7	-0.6	1.1	-1.0	2.1	0.2
Falls in the last year	0.5	0.6	1.9	-0.3	-0.6	-0.4	-1.1	-0.0	-0.3	1.4	-1.1
Hair/balding pattern: Pattern 3	0.6	0.9	2.7	-0.3	0.4	0.1	1.5	-1.6	0.2	-1.4	0.4
Number of live births	0.3	0.5	1.2	0.4	1.1	1.1	0.1	-0.1	0.7	-0.8	0.1
Forced expiratory volume in 1-second (FEV1)	1.9	6.5	20.7	-1.0	0.8	2.2	4.5	-1.0	2.2	-3.8	2.2
Pulse rate	0.5	0.9	4.1	0.6	-2.0	0.2	-0.2	1.6	0.3	-0.1	-0.0
Happiness	0.6	0.7	2.0	-0.6	-0.1	0.7	-0.5	1.4	0.9	-0.7	1.1
Noisy workplace	1.5	1.9	5.4	-2.3	-0.1	-2.0	0.0	-1.3	-2.0	0.5	-0.1
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.5	-0.1	-0.1	-0.2	0.7	0.2	0.4	-1.9	0.6
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	4.5	-0.8	-2.0	-2.1	-1.1	-0.3	-1.2	-0.5	0.5
Mouth/teeth dental problems: Dentures	0.7	1.1	2.3	0.9	-0.5	1.5	-1.4	-1.4	0.9	0.5	-0.8
Asthma	1.1	2.1	7.4	-0.8	2.7	0.8	2.3	0.3	0.2	1.1	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	6.8	0.1	0.8	0.6	2.6	0.2	0.6	0.6	0.9
Medication: Cholesterol lowering	1.3	1.9	6.4	-0.9	-1.6	-1.2	-2.5	-1.1	-1.7	0.2	0.2
Depression (self-reported)	0.5	0.6	1.7	-0.4	0.1	-1.3	-0.7	0.6	-1.2	0.7	0.6
Medication: Lansoprazole	0.8	0.9	3.7	0.4	0.5	-0.3	1.3	0.3	0.1	1.9	-1.0
Prospective memory result	0.9	1.1	4.5	1.2	0.9	0.1	2.1	-0.4	0.4	1.0	-0.6
Lung cancer (father)	1.5	1.7	4.2	-1.1	0.6	-2.0	-1.2	-1.4	-2.0	0.8	-0.0
Illnesses of mother	0.3	0.3	1.4	-0.1	1.2	0.4	-0.6	-0.4	0.7	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	8.1	24.9	-1.2	0.5	2.5	5.0	-2.3	1.9	-4.0	2.6
Pulse wave Arterial Stiffness index	1.4	1.6	6.0	0.9	-2.5	0.0	-1.4	0.3	0.3	0.7	-1.9
Impedance of arm (left)	0.5	2.3	6.9	-0.7	1.4	-1.2	2.6	1.0	-1.1	-0.2	2.3
Arm fat mass (right)	1.3	5.4	22.2	-0.7	4.1	1.1	4.7	0.3	1.1	-1.0	-0.2
Trunk predicted mass	2.2	12.6	35.0	2.2	0.4	5.9	3.4	-0.6	5.4	-4.4	0.7
Standing height	2.9	28.8	57.2	2.2	1.3	7.6	7.3	0.3	6.9	-6.7	4.5
Length of working week for main job	1.0	1.1	2.6	-0.6	0.1	-1.2	-0.7	-1.6	-1.2	1.2	-1.0
Exposure to tobacco smoke at home	0.5	0.5	1.0	1.0	0.0	0.9	-0.9	0.9	0.8	0.5	0.2
Breastfed as a baby	0.5	0.7	2.6	-0.0	-1.0	-0.2	-0.7	-1.6	-0.3	-1.1	0.0
Tense / ‘highly strung’	0.5	0.8	3.5	-0.7	1.0	-0.1	0.1	1.9	-0.3	1.0	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	1.7	-1.1	1.3	1.1	0.1	0.5	0.8	-0.0	-0.6
Hair/balding pattern: Pattern 4	0.3	0.8	1.6	1.3	-1.3	0.7	0.6	-0.8	-0.0	-0.9	0.9
Birth weight of first child	0.6	1.0	4.2	0.3	0.2	0.3	2.0	-1.3	0.1	-1.0	1.0
Peak expiratory flow (PEF)	0.9	2.1	6.0	-1.8	-2.5	-0.8	-0.2	-0.0	-0.2	-2.2	1.6
Pulse wave reflection index	2.0	2.5	5.9	1.0	-2.4	-0.7	-1.5	-1.9	-0.3	1.1	-2.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.0	-0.6	-0.0	-0.6	-0.4	0.6	-0.2	1.2	-1.4
Loud music exposure frequency	0.7	0.8	2.0	-1.3	-1.4	-1.1	-0.3	-0.1	-0.9	-0.2	0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.6	0.3	-0.7	0.3	0.1	1.6	0.8	-1.4	-0.0
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.4	1.0	-0.4	0.9	1.6	1.3	1.8	-0.1	0.6
Blood clot in the leg (DVT)	0.7	0.9	2.1	-0.2	1.3	0.8	-0.0	1.3	0.8	-1.4	0.5
Medication: Paracetamol	1.4	2.3	6.5	-1.5	1.6	-1.5	2.5	0.9	-1.3	1.4	0.7
Headache pain in last month	0.5	0.8	2.3	-0.6	0.8	0.1	1.1	1.1	0.0	0.7	1.5
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.2	0.4	1.5	0.6	1.4	0.7	1.5	-0.4	-0.0
Glaucoma (self-reported)	0.3	0.4	0.8	-0.5	-0.8	-0.7	-0.3	-0.9	-0.6	-0.1	0.4
Gout (self-reported)	1.4	2.0	5.3	-0.0	2.3	-1.1	1.1	0.1	-1.2	2.1	-1.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	5.9	-0.5	-1.7	-0.0	-2.4	-0.4	-0.4	-0.6	-0.2
Medication: Amlodipine	0.4	0.5	1.8	-0.0	-0.2	-0.6	0.4	-1.3	-1.2	-0.3	0.3
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.6	-1.2	-0.2	-0.6	0.8	0.1	-1.2	1.8	-1.9
Birth weight	0.6	1.3	7.8	-0.4	-1.0	-0.2	-0.2	2.8	0.8	0.7	-0.6
Chronic bronchitis/emphysema (mother)	1.0	1.2	4.0	-0.1	-0.8	0.9	-0.4	2.0	1.2	-1.4	0.7
High blood pressure (siblings)	0.4	0.5	2.0	0.2	-0.1	-0.1	1.3	1.4	-0.4	0.6	-0.1
Forced vital capacity (FVC), Best measure	3.5	12.8	38.6	-0.4	1.4	3.8	6.2	-2.1	3.0	-4.5	3.5
Body fat percentage	1.5	6.0	23.0	-1.7	4.4	-0.9	4.8	1.0	-0.8	0.5	-0.0
Leg fat percentage (right)	1.0	3.6	10.2	-1.7	3.2	-2.2	2.3	1.1	-1.7	1.1	-0.5
Arm fat-free mass (right)	1.7	8.6	23.5	1.8	1.3	4.8	3.3	-0.1	4.4	-3.1	0.7
Exposure to tobacco smoke outside home	0.2	0.2	1.2	-0.2	1.1	-0.1	0.5	-0.2	-0.1	0.3	0.3
Comparative body size at age 10	0.1	0.4	1.4	-0.2	0.3	-0.6	0.5	0.1	-0.2	1.2	-1.0
Number of full brothers	1.2	1.5	6.1	-0.7	-1.9	-0.7	-2.5	0.6	0.6	-0.2	-0.7
Worry too long after embarrassment	0.7	1.2	4.6	0.0	0.0	-0.7	-2.1	1.1	-0.2	1.0	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	3.3	-1.8	-0.8	0.1	-0.4	0.9	-0.0	-0.1	0.6
Wheeze or whistling in the chest in last year	0.5	0.9	3.3	-0.9	1.0	-0.3	1.8	0.0	-0.9	0.1	0.9
Number of children fathered	1.3	1.4	3.7	1.9	-1.6	1.2	0.6	0.1	1.3	0.4	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	4.1	-0.6	0.9	0.1	-1.9	-0.2	0.0	-1.3	2.0
Age at first live birth	0.2	0.4	1.7	-0.4	-0.2	0.4	0.7	-0.1	0.5	-1.3	0.4
Pulse wave peak to peak time	2.0	2.4	7.4	-1.0	2.7	0.3	2.0	-0.6	-0.1	-1.2	2.3
Health satisfaction	0.5	0.6	1.9	-0.4	-0.6	0.8	-0.9	-1.4	-0.0	0.7	-0.6
Shortness of breath walking on level ground	1.0	1.2	2.7	1.3	1.1	0.7	0.6	1.0	0.4	1.6	-1.5
Qualifications: College or University degree	0.4	1.2	3.3	-0.6	-1.3	-1.8	0.7	-0.5	-1.4	-1.1	0.4
Eye problems/disorders: None of the above	3.1	3.6	5.8	2.4	0.9	2.3	2.0	-1.4	2.4	-2.2	0.8
Mouth/teeth dental problems: Loose teeth	2.2	2.7	7.9	0.7	2.0	0.6	0.5	2.8	1.4	-1.6	1.9
Emphysema/chronic bronchitis	1.2	1.4	3.2	0.5	1.8	0.8	1.0	1.6	1.4	0.9	-0.9
Medication for pain relief, constipation, heartburn	2.6	4.5	18.4	2.0	-2.1	0.8	-4.3	-1.5	0.9	-1.0	-2.0
Neck or shoulder pain in last month	0.1	0.1	0.7	0.2	0.4	0.3	0.3	-0.3	0.1	0.1	-0.8
Medication: Blood pressure	0.4	0.7	1.9	0.1	-1.2	-0.6	0.3	-0.9	-1.4	0.1	0.7
Angina (self-reported)	1.0	1.3	4.7	-0.7	-0.6	-1.9	-0.6	-0.6	-2.2	0.7	0.2
Migraine (self-reported)	3.2	4.0	8.7	-0.4	1.6	2.5	1.0	-0.2	2.2	-3.0	2.9
Medication: Ibuprofen	0.9	1.1	3.9	0.2	0.7	1.0	2.0	0.5	1.1	-0.2	1.5
Medication: Allopurinol	1.3	1.7	3.6	1.3	1.5	-0.2	0.9	1.2	-0.1	1.9	-1.9
Medication: Omeprazole	0.4	0.5	1.8	-1.4	0.7	-0.3	1.2	0.2	-0.4	0.1	0.2
Medication: Seretide 50 evohaler	1.5	1.8	10.5	0.2	1.7	0.3	3.2	-0.4	-0.1	0.5	-0.2
Mean time to correctly identify matches	0.5	0.9	2.4	1.5	-0.6	0.8	-1.1	0.9	1.3	-0.6	0.2
Heart disease (mother)	0.7	0.8	2.6	-0.5	-1.6	-0.9	-0.6	0.3	-0.9	-0.2	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.9	-1.4	1.5	-0.3	-1.2	-0.2	-0.8	1.7	-0.4
Whole body fat mass	1.7	7.0	31.4	-0.9	4.5	1.1	5.6	0.5	1.0	-0.9	0.3
Leg fat mass (right)	1.0	3.8	15.4	-0.8	3.6	0.5	3.9	0.7	0.6	-0.5	-0.0
Arm predicted mass (right)	1.6	8.4	23.9	1.7	1.3	4.9	3.0	-0.1	4.5	-3.1	0.6
Pulse rate, automated reading	0.2	0.7	1.5	0.2	-1.2	-0.9	-0.6	0.8	-1.1	1.2	0.3
Alcohol intake frequency.	0.7	1.5	4.0	0.3	1.6	2.0	1.4	1.2	1.4	-0.2	-0.0
Comparative height size at age 10	3.6	19.9	41.2	3.0	1.8	5.9	6.4	0.4	5.4	-5.3	3.6
Number of full sisters	1.8	2.2	6.7	-2.6	1.3	-1.8	0.3	-1.4	-1.9	-0.1	-0.5
Suffer from ‘nerves’	1.2	1.9	5.2	-2.3	0.4	-1.6	-1.3	-0.1	-1.6	1.1	-1.3
Overall health rating	0.8	1.6	7.0	-0.3	-0.2	-0.9	-0.3	-0.5	-1.6	2.6	-1.6
Chest pain or discomfort	0.5	0.8	2.1	-0.9	1.4	-0.3	0.8	0.7	-0.1	1.4	-0.3
Had major operations	0.5	0.6	1.6	0.5	-0.1	-0.6	-1.2	-0.6	-0.5	1.3	-0.8
Age at last live birth	0.4	0.5	1.9	-0.5	0.6	0.5	1.4	-0.1	0.8	-0.4	0.7
Family relationship satisfaction	0.7	0.8	2.2	-1.3	0.9	0.2	-1.5	1.0	0.4	0.3	-0.8
Leg pain on walking	1.0	1.3	2.6	1.2	1.6	1.4	1.3	1.0	0.9	0.1	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	3.3	-1.8	0.1	-0.7	0.2	0.9	-0.5	-0.3	1.4
Commuting to job workplace: Car/motor vehicle	1.0	1.2	2.6	0.9	0.5	1.2	0.7	1.6	1.6	-0.9	0.9
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.5	0.7	1.6	0.5	-0.2	-1.3	-0.4	1.1	-0.8
Medication: Aspirin	0.8	1.1	3.3	-1.2	-0.5	-0.8	0.9	-0.2	-1.2	-0.7	1.8
Supplements: Vitamin C	1.2	1.5	3.1	-1.4	0.8	-1.7	-0.4	0.7	-1.5	1.6	0.8
Knee pain experienced in last month	1.2	1.9	6.4	1.0	2.3	1.1	2.5	0.4	0.9	0.6	-0.2
Hypertension (Self-reported)	0.4	1.2	2.7	1.3	1.4	-0.3	1.0	0.5	-0.7	-1.2	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.6	-1.6	0.7	-1.6	1.0	-0.0	-1.5	-0.0	1.4
Illnesses of father: Heart disease	1.1	1.5	3.1	-1.7	-0.0	-1.8	0.7	1.2	-1.7	0.3	0.9
Illnesses of siblings: Diabetes	0.9	1.0	2.2	-1.4	-0.9	-1.5	-1.1	-0.4	-1.0	-0.8	0.6
Smoking status: Previous	0.2	0.3	1.1	-0.6	-0.3	0.1	-0.5	-1.0	0.5	-0.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.3	12.6	-0.8	-0.1	2.0	2.1	0.0	2.5	-3.5	2.5
Whole body fat-free mass	2.3	13.0	34.9	2.0	1.4	5.9	4.2	-0.4	5.3	-4.1	0.6
Leg fat-free mass (right)	2.3	12.5	30.5	1.4	2.5	5.5	4.8	-0.1	4.9	-3.6	0.3
Arm fat percentage (left)	1.2	5.0	19.4	-1.3	4.4	-0.3	4.2	0.7	-0.2	0.2	-0.3
Average weekly red wine intake	0.9	1.3	4.6	-1.1	-1.3	-0.9	0.1	-2.2	-0.7	-0.9	-0.7
Handedness (chirality/laterality): Left-handed	1.5	1.8	3.7	-1.3	0.5	-1.8	1.0	-0.3	-1.9	1.1	-1.7
Mood swings	1.4	2.5	10.0	0.4	3.2	1.0	0.8	2.3	1.6	-0.0	1.0
Loneliness, isolation	1.4	1.9	5.0	1.2	1.7	2.2	0.3	1.5	1.9	0.3	-0.0
Long-standing illness, disability or infirmity	0.6	0.9	3.3	-0.8	0.4	0.8	1.2	1.8	0.7	-0.4	0.3
Ever had bowel cancer screening	0.3	0.3	0.6	0.7	0.1	0.8	0.7	-0.6	0.6	-0.0	-0.0
Diabetes diagnosed by doctor	0.2	0.3	1.2	-0.9	0.3	0.1	-0.4	0.4	0.2	-1.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	3.8	0.2	-0.9	0.2	-0.8	-0.7	0.1	-2.0	0.9
Friendships satisfaction	1.0	1.3	3.6	-1.9	1.2	-1.0	-0.8	1.6	-0.2	-0.4	0.9
Qualifications: nursing, teaching	0.4	0.7	2.3	-0.6	0.5	-0.0	1.5	0.1	-0.0	-1.4	0.8
Commuting to job workplace: Walk	1.0	1.1	2.0	-0.7	-1.0	-1.1	-1.4	-1.1	-0.8	-0.6	1.4
Eye problems/disorders: Cataract	2.9	3.4	7.7	-2.8	-0.9	-1.9	-1.6	0.8	-2.1	2.5	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.5	2.5	6.2	0.1	0.3	0.8	2.5	2.2	1.1	-1.2	2.2
Medication for cholesterol	0.9	1.4	3.6	1.3	-1.2	1.9	-0.8	-0.1	1.6	-0.6	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.2	2.6	1.6	0.7	1.4	1.0	0.7	1.2	-0.6	1.2
Back pain experienced in last month	0.3	0.4	1.1	0.8	0.1	0.6	0.6	0.9	1.0	-0.2	-0.1
Mineral and other dietary supplements	2.1	2.8	7.1	1.1	-1.8	1.2	-1.1	-0.3	1.3	-2.7	2.6
Breast cancer (self-reported)	1.0	1.2	2.9	1.7	0.8	1.5	-0.5	-0.2	1.1	1.0	-1.0
Asthma (self-reported)	1.1	2.3	6.7	-0.9	2.6	0.6	2.2	0.4	0.0	1.7	-1.6
Osteoporosis (self-reported)	1.5	1.8	5.5	0.4	-0.6	0.1	-2.0	1.2	0.1	2.3	-1.8
Osteoarthritis (self-reported)	1.9	2.4	11.3	-1.3	3.4	-0.5	1.7	-0.7	-0.5	1.1	-1.2
Medication: Aspirin	0.6	0.8	2.1	-1.3	0.1	-0.7	0.8	-0.1	-1.2	-0.6	1.4
Medication: Gliclazide	0.4	0.5	1.5	0.2	-0.4	0.8	0.2	-1.2	0.5	-1.1	0.4
Illnesses of father: None of the above (group 1)	1.0	1.3	4.5	2.1	-0.6	0.1	-1.4	-1.0	-0.1	0.4	-1.5
Smoking status: Current	1.2	1.9	3.8	-0.2	-1.5	-0.9	-1.8	-1.4	-1.6	2.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	7.5	0.3	-0.7	0.6	2.4	-2.7	-0.1	-1.0	-0.1
Whole body water mass	2.3	13.0	35.2	1.9	1.4	5.9	4.1	-0.3	5.3	-4.1	0.6
Leg predicted mass (right)	2.3	12.5	30.8	1.4	2.5	5.5	4.8	-0.1	5.0	-3.6	0.3
Arm fat mass (left)	1.3	5.5	22.7	-0.5	4.1	1.3	4.8	0.3	1.2	-0.9	0.0
Number of self-reported non-cancer illnesses	0.2	0.4	1.8	-0.6	0.2	-0.6	0.3	-0.1	-0.7	-0.4	1.3
Average weekly champagne plus white wine intake	3.0	4.1	8.9	3.0	2.1	2.5	2.0	-0.1	2.4	-1.7	0.5
Miserableness	1.4	2.5	11.9	0.4	2.0	0.2	-1.0	3.5	0.9	1.4	-0.5
Guilty feelings	1.7	2.5	6.5	1.4	2.4	1.0	-0.6	2.5	2.0	-0.3	-0.4
Wears glasses or contact lenses	0.9	1.0	2.2	-1.2	-0.7	-1.5	-0.6	-0.7	-1.4	0.2	1.1
Ever taken oral contraceptive pill	1.2	1.3	3.3	-1.8	0.4	-1.8	-1.0	1.0	-1.1	-0.4	0.3
Hearing aid user	0.2	0.3	0.9	-0.2	-0.9	-0.3	-0.4	-0.0	-0.2	-1.0	0.2
Mother’s age at death	0.3	0.3	0.8	-0.9	-0.9	0.4	-0.2	-0.4	-0.1	-0.6	0.7
Financial situation satisfaction	1.2	1.5	3.5	-1.9	0.7	-1.2	0.2	-1.6	-1.5	-0.6	1.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	4.3	-0.9	-0.4	0.3	0.4	2.1	0.5	0.2	0.4
Commuting to job workplace: Public transport	1.3	1.5	2.6	-0.3	-0.8	-1.3	-1.6	-1.6	-1.6	-0.0	-1.3
Eye problems/disorders: Glaucoma	0.3	0.4	0.9	0.8	-0.6	0.1	-0.9	0.8	0.4	0.6	-0.2
Medication: Blood pressure	0.4	0.8	1.7	0.1	1.3	-0.7	1.2	1.2	-0.3	-0.7	0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.4	1.9	-0.7	1.4	0.3	0.2	0.6	-0.4	0.7	0.1
Supplements: Fish oil (including cod liver oil)	2.1	2.7	5.8	-1.0	1.8	-1.2	1.4	-1.0	-1.8	2.4	-2.0
High cholesterol (Self-reported)	0.5	0.9	2.3	-1.0	0.6	-1.5	-0.7	-0.0	-1.5	0.1	0.7
Medication: Bendroflumethiazide	0.8	1.2	4.0	1.1	-0.4	-0.5	-0.6	0.8	-0.8	1.5	-2.0
Medication: Paracetamol	1.3	2.0	7.7	-1.2	1.8	-0.5	2.8	0.7	-0.3	0.1	1.6
Medication: Lisinopril	0.4	0.5	1.6	0.0	-1.3	-0.2	0.0	1.3	-0.3	0.6	-0.2
Medication: Atorvastatin	0.1	0.2	0.4	-0.3	-0.6	0.3	-0.7	-0.4	-0.1	0.3	0.5
Illnesses of father: High blood pressure	1.3	1.7	4.3	-2.1	0.6	-1.5	0.8	1.5	-1.3	0.5	1.3
Alcohol drinker status: Never	0.8	1.0	3.6	0.9	1.2	1.1	1.9	0.5	0.4	0.4	0.6
Ever smoked	1.6	2.8	8.3	-0.8	-2.0	-1.3	-1.2	-2.9	-1.5	0.9	-1.8
Basal metabolic rate	2.1	11.7	27.7	1.5	2.2	5.3	4.7	-0.1	4.8	-3.8	0.6
Leg fat percentage (left)	1.1	3.9	10.0	-2.1	3.2	-2.2	2.5	0.8	-1.9	1.2	-0.6
Arm fat-free mass (left)	1.6	8.1	20.9	1.2	1.4	4.6	3.5	-0.4	4.1	-3.2	0.5
Number of operations (self-reported)	1.0	1.5	3.5	1.9	0.2	1.7	-0.6	0.7	1.7	0.3	-1.4
Average weekly beer plus cider intake	0.4	0.6	1.7	-1.3	0.5	-0.6	0.4	-0.2	-0.9	1.1	-0.7
Irritability	0.1	0.2	0.5	0.2	0.1	-0.4	-0.6	0.7	0.1	0.6	0.6
Risk taking	1.0	1.5	2.7	1.5	-1.4	1.5	-0.2	0.8	1.6	-1.0	1.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	3.5	-0.5	0.8	-0.2	1.9	-0.3	-0.5	-0.9	0.4
Fractured/broken bones in last 5 years	3.6	4.7	10.5	1.4	-2.6	-0.8	-2.8	-0.1	-1.3	2.9	-3.2
Age started oral contraceptive pill	0.9	1.1	3.1	1.1	-0.5	0.5	-1.4	1.8	0.9	-1.1	-0.2
Diastolic blood pressure, automated reading	0.4	1.4	4.7	-1.5	0.4	-0.4	1.1	0.4	-0.5	-1.4	2.2
Ever depressed for a whole week	1.0	1.3	5.5	-2.4	-0.7	-1.1	-1.5	-0.7	-0.4	-0.1	-0.1
Unable to work because of sickness or disability	0.4	0.5	1.3	-1.1	0.0	-0.7	0.7	-0.1	-1.2	0.9	0.2
Commuting to job workplace: Cycle	1.0	1.2	3.0	0.6	-1.0	1.6	0.2	0.3	1.0	1.2	-1.7
Myopia	0.2	0.3	1.1	-0.2	0.3	-0.7	-0.2	-1.0	-0.8	-0.2	0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.8	-0.5	-0.6	1.2	-0.7	-0.3	1.3	1.1	-1.7
Cholesterol lowering medication	0.8	1.2	3.3	-0.5	1.3	-1.8	0.6	0.9	-1.4	0.7	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.5	-1.1	0.9	0.2	2.1	0.4	0.1	-0.1	0.2
Pain experienced in last month	0.6	1.0	2.3	-0.1	-0.9	-1.1	-1.5	-1.1	-1.3	-0.7	0.4
Supplements: Calcium	0.6	0.7	1.5	-0.3	1.2	0.6	-0.9	0.9	0.5	0.8	-1.0
Basal cell carcinoma (self-reported)	0.5	0.6	4.2	-0.4	-0.1	-0.1	0.4	-0.3	0.5	-2.0	0.4
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.0	0.6	-1.1	0.1	-0.7	0.7	-0.1	-0.6	1.4
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.2	-0.2	1.3	1.1	0.3	1.0	1.0	-1.8	1.1
Heart disease (siblings)	1.0	1.3	2.5	0.0	-1.1	-1.4	-1.6	1.2	-0.8	1.5	-0.0
Alcohol drinker status: Previous	0.4	0.4	2.1	-1.1	1.4	-0.0	0.1	0.1	0.1	0.1	0.3
Pack years of smoking	0.2	0.2	0.8	0.9	0.0	0.5	-0.6	-0.1	0.5	0.4	-0.2
Impedance of whole body	0.7	3.7	9.0	-1.7	0.6	-3.0	1.4	1.1	-2.5	0.3	2.7
Leg fat mass (left)	1.0	4.1	16.8	-1.0	3.7	0.5	4.1	0.5	0.5	-0.4	-0.1
Arm predicted mass (left)	1.7	8.8	22.4	1.1	1.2	4.7	3.7	-0.6	4.3	-3.5	0.7