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Traits
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Leg fat-free mass (left)
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chr2:55,401,562-56,843,605
Best TWAS P=4.64e-18 · Best GWAS P=1.28e-21 conditioned to 7.94e-06
55.4M
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
EFEMP1
0.19
0.10
lasso
8
0.08
3.7e-03
-7.8
-8.7
4.6e-18
0.78
0.04
0.7
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
EFEMP1
0.29
0.14
enet
37
0.19
2.2e-24
-5.9
-5.7
1.2e-08
0.64
1.00
0.0
FALSE