TWAS
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Traits
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Traits
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Leg fat-free mass (left)
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chr2:111,392,259-112,621,199
Best TWAS P=2.86e-10 · Best GWAS P=3.28e-10 conditioned to 1
111.4M
111.6M
111.8M
112M
112.2M
112.4M
112.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
BCL2L11
0.04
0.04
lasso
2
0.03
2e-04
6.3
-6.3
2.9e-10
-1.00
0.00
0.99
TRUE
2
The Cancer Genome Atlas
Colon Adenocarcinoma
BCL2L11
0.07
0.01
blup
71
0.06
2e-04
-4.8
-5.2
2.0e-07
-0.85
0.02
0.94
FALSE