Best TWAS P=7.41e-08 · Best GWAS P=2.99e-07 conditioned to 0.0875
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Putamen basal ganglia | GS1-124K5.4 | 0.31 | 0.32 | enet | 23 | 0.36 | 1.7e-09 | 4.5 | 5.4 | 7.4e-08 | 0.74 | 0.08 | 0.86 | TRUE |
2 | GTEx | Muscle Skeletal | VKORC1L1 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-03 | 4.6 | 5.3 | 1.1e-07 | 0.80 | 0.02 | 0.88 | FALSE |