[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr7:71,935,903-73,789,730

Best TWAS P=2.74e-10 · Best GWAS P=2.55e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC30 0.13 0.07 enet 32 0.07 2.7e-09 4.7 5.3 1.2e-07 0.30 0.97 0.03 FALSE
2 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 5.2 5.8 6.7e-09 0.85 0.04 0.96 FALSE
3 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 5.2 5.8 6.5e-09 0.80 0.10 0.88 FALSE
4 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 5.8 6.2 7.1e-10 0.92 0.01 0.99 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 5.8 5.7 1.0e-08 0.74 0.02 0.95 FALSE
6 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 5.8 5.9 3.9e-09 0.83 0.08 0.91 FALSE
7 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 5.6 -5.8 6.3e-09 -0.88 0.02 0.70 FALSE
8 GTEx Testis MLXIPL 0.10 0.00 lasso 3 0.00 3.3e-01 4.1 5.4 5.4e-08 0.75 0.02 0.61 FALSE
9 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 5.2 6.2 5.7e-10 0.88 0.02 0.98 FALSE
10 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 6.3 6.3 2.7e-10 0.96 0.01 0.99 TRUE
11 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 6.3 6.1 1.2e-09 0.98 0.00 1.00 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 6.3 6.3 3.3e-10 0.98 0.00 0.98 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 6.3 5.3 1.3e-07 0.93 0.00 1.00 FALSE