Best TWAS P=4.86e-16 · Best GWAS P=5.67e-15 conditioned to 8.15e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TRPS1 | 0.05 | 0.02 | enet | 19 | 0.02 | 0.0024 | 7.7 | -5.2 | 2.0e-07 | 0.07 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TRPS1 | 0.04 | 0.03 | blup | 102 | 0.01 | 0.0096 | 6.7 | -8.1 | 4.9e-16 | 0.48 | 0.07 | 0.14 | TRUE |