Best TWAS P=1.34e-11 · Best GWAS P=6.67e-13 conditioned to 2.1e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NOV | 0.06 | 0.02 | enet | 8 | 0.05 | 1.5e-06 | -3.8 | -5.2 | 2.1e-07 | -0.04 | 0.18 | 0.82 | FALSE |
| 2 | GTEx | Artery Aorta | NOV | 0.12 | 0.05 | enet | 18 | 0.04 | 3.7e-03 | -4.4 | -5.4 | 5.5e-08 | -0.05 | 0.05 | 0.78 | FALSE |
| 3 | GTEx | Colon Sigmoid | NOV | 0.15 | 0.16 | lasso | 4 | 0.15 | 6.6e-06 | -6.7 | -6.7 | 2.6e-11 | 0.05 | 0.05 | 0.93 | FALSE |
| 4 | GTEx | Lung | NOV | 0.06 | 0.02 | enet | 23 | 0.03 | 2.5e-03 | -3.0 | -5.2 | 2.4e-07 | -0.02 | 0.23 | 0.36 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | NOV | 0.11 | 0.03 | lasso | 7 | 0.04 | 1.4e-04 | -6.5 | -5.9 | 2.9e-09 | 0.01 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | NOV | 0.03 | 0.00 | blup | 42 | 0.01 | 5.3e-02 | -6.5 | -6.7 | 1.8e-11 | 0.04 | 0.02 | 0.77 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | NOV | 0.31 | 0.10 | blup | 42 | 0.10 | 1.2e-06 | -7.0 | -5.7 | 9.9e-09 | 0.05 | 0.01 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NOV | 0.11 | 0.02 | enet | 15 | 0.05 | 2.9e-03 | -7.0 | -6.8 | 1.3e-11 | -0.02 | 0.01 | 0.62 | TRUE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NOV | 0.04 | 0.05 | blup | 42 | 0.05 | 8.7e-06 | -6.6 | -5.7 | 9.4e-09 | 0.04 | 0.04 | 0.96 | FALSE |