Best TWAS P=4.24e-10 · Best GWAS P=1.36e-13 conditioned to 4.92e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RAD52 | 0.14 | 0.07 | lasso | 3 | 0.10 | 1.1e-05 | -5.1 | -6.2 | 4.2e-10 | -0.44 | 0.38 | 0.55 | TRUE |
| 2 | GTEx | Artery Tibial | B4GALNT3 | 0.49 | 0.24 | enet | 24 | 0.34 | 6.5e-28 | 4.5 | -5.3 | 1.1e-07 | -0.02 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Testis | RAD52 | 0.29 | 0.19 | lasso | 3 | 0.18 | 2.3e-08 | 5.7 | -5.2 | 2.4e-07 | -0.49 | 0.63 | 0.36 | FALSE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | RAD52 | 0.25 | 0.13 | blup | 66 | 0.19 | 1.1e-06 | 6.9 | -6.0 | 2.4e-09 | -0.61 | 0.01 | 0.99 | FALSE |