[Hub]/) : Traits : Leg predicted mass (left) :

chr12:14,230,553-15,652,812

Best TWAS P=1.99e-10 · Best GWAS P=1.53e-10 conditioned to 0.122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Left Ventricle H2AFJ 0.16 0.07 lasso 8 0.05 1.1e-03 -6.2 -6.1 7.9e-10 0.85 0.02 0.98 FALSE
2 GTEx Liver H2AFJ 0.18 0.11 lasso 8 0.04 2.7e-02 -6.2 -5.3 1.0e-07 0.79 0.03 0.82 FALSE
3 ROSMAP Brain Pre-frontal Cortex WBP11 0.10 0.05 lasso 4 0.06 1.2e-08 -4.7 6.2 7.5e-10 -0.72 0.06 0.94 FALSE
4 YFS Blood H2AFJ 0.05 0.02 bslmm 360 0.03 2.9e-10 -6.2 -5.3 8.8e-08 0.68 0.01 0.99 FALSE
5 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C12orf60 0.12 0.07 enet 8 0.07 5.4e-05 4.3 5.5 4.4e-08 -0.64 0.08 0.80 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma WBP11 0.03 0.03 blup 57 0.02 2.3e-03 -6.2 6.4 2.0e-10 -0.90 0.01 0.94 TRUE
7 The Cancer Genome Atlas Thyroid Carcinoma C12orf60 0.16 0.16 enet 10 0.18 1.3e-17 4.3 5.6 2.4e-08 -0.61 0.99 0.00 FALSE