[Hub]/) : Traits : Leg predicted mass (left) :

chr13:114,302,502-115,106,996

Best TWAS P=8.41e-09 · Best GWAS P=3.38e-07 conditioned to 0.364

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue CDC16 0.25 0.28 lasso 6 0.26 6.9e-14 -5.1 -5.3 1.0e-07 0.97 0.01 0.98 FALSE
2 GTEx Breast Mammary Tissue (Male) CDC16 0.23 0.08 enet 11 0.09 3.8e-03 -4.5 -5.6 2.4e-08 0.85 0.03 0.83 FALSE
3 GTEx Breast Mammary Tissue (Female) CDC16 0.25 0.22 enet 28 0.22 3.6e-07 -5.1 -5.3 1.3e-07 0.92 0.02 0.98 FALSE
4 GTEx Colon Transverse CDC16 0.18 0.23 lasso 5 0.21 3.2e-10 -5.1 -5.2 2.1e-07 0.98 0.02 0.98 FALSE
5 GTEx Esophagus Gastroesophageal Junction CDC16 0.09 0.05 lasso 2 0.02 5.7e-02 -5.1 -5.1 2.8e-07 1.00 0.02 0.88 FALSE
6 GTEx Nerve Tibial CDC16 0.23 0.23 enet 19 0.26 9.5e-19 -5.0 -5.2 2.6e-07 0.95 0.01 0.98 FALSE
7 GTEx Skin Sun Exposed Lower leg CDC16 0.31 0.33 lasso 7 0.33 4.1e-28 -4.9 -5.1 2.9e-07 0.98 0.02 0.98 FALSE
8 GTEx Testis CDC16 0.32 0.30 enet 26 0.35 4.4e-16 -5.1 -5.8 8.4e-09 0.94 0.01 0.98 TRUE
9 The Cancer Genome Atlas Colon Adenocarcinoma CDC16 0.06 0.04 lasso 5 0.03 5.9e-03 -5.0 -5.3 8.9e-08 0.88 0.01 0.90 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CDC16 0.04 0.01 blup 49 0.03 7.7e-03 -5.1 -5.2 2.3e-07 0.96 0.02 0.93 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma CDC16 0.11 0.09 blup 49 0.09 1.8e-04 -5.0 -5.4 6.1e-08 0.98 0.02 0.96 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma CDC16 0.06 0.09 lasso 3 0.09 3.3e-09 -5.1 -5.4 8.7e-08 0.98 0.01 0.99 FALSE