Best TWAS P=6.18e-10 · Best GWAS P=2.33e-11 conditioned to 0.000393
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | UGGT2 | 0.09 | 0.03 | enet | 15 | 0.04 | 4.6e-03 | 3.1 | -5.3 | 1.2e-07 | -0.49 | 0.39 | 0.25 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | UGGT2 | 0.22 | 0.00 | enet | 27 | 0.01 | 2.4e-01 | -4.7 | -5.5 | 3.2e-08 | -0.59 | 0.08 | 0.40 | FALSE |
| 3 | GTEx | Colon Sigmoid | UGGT2 | 0.23 | 0.09 | lasso | 8 | 0.09 | 3.6e-04 | -3.9 | -5.3 | 1.3e-07 | -0.61 | 0.41 | 0.14 | FALSE |
| 4 | GTEx | Colon Transverse | DNAJC3 | 0.10 | 0.06 | lasso | 7 | 0.05 | 1.8e-03 | 3.7 | -5.4 | 6.3e-08 | -0.86 | 0.02 | 0.93 | FALSE |
| 5 | GTEx | Esophagus Muscularis | UGGT2 | 0.17 | 0.15 | lasso | 6 | 0.19 | 1.9e-11 | -4.1 | -5.2 | 2.4e-07 | -0.56 | 0.95 | 0.05 | FALSE |
| 6 | GTEx | Skin Not Sun Exposed Suprapubic | UGGT2 | 0.16 | 0.13 | enet | 11 | 0.17 | 9.5e-10 | -4.1 | -6.2 | 6.2e-10 | -0.64 | 0.70 | 0.29 | TRUE |
| 7 | GTEx | Small Intestine Terminal Ileum | UGGT2 | 0.20 | 0.00 | enet | 16 | 0.02 | 1.2e-01 | -4.2 | -5.3 | 1.3e-07 | -0.63 | 0.07 | 0.36 | FALSE |