[Hub]/) : Traits : Leg predicted mass (left) :

chr1:149,672,809-150,515,021

Best TWAS P=4.49e-10 · Best GWAS P=1.24e-18 conditioned to 1.94e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial HIST2H2AA3 0.22 0.02 enet 20 0.12 1.8e-09 8.1 6.1 1.2e-09 0.70 0.00 1.00 TRUE
2 GTEx Artery Tibial RP11-196G18.22 0.25 0.05 lasso 5 0.07 1.8e-06 3.1 6.0 1.5e-09 0.78 0.01 0.98 FALSE
3 GTEx Artery Tibial RP11-196G18.24 0.31 0.08 enet 26 0.10 6.1e-08 8.1 5.8 8.8e-09 0.72 0.00 0.99 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma C1orf54 0.06 0.02 enet 13 0.02 1.2e-05 4.7 -6.2 4.5e-10 -0.15 0.00 0.90 TRUE
5 The Cancer Genome Atlas Brain Lower Grade Glioma MRPS21 0.13 0.13 enet 10 0.13 1.7e-14 -3.6 5.2 2.6e-07 0.07 0.10 0.60 FALSE