[Hub]/) : Traits : Leg predicted mass (left) :

chr14:24,098,631-25,489,283

Best TWAS P=9.83e-12 · Best GWAS P=9.36e-12 conditioned to 0.00513

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Thyroid ADCY4 0.13 0.13 lasso 6 0.09 1.0e-07 4.0 5.2 2.4e-07 0.51 0.49 0.51 FALSE
2 METSIM Adipose ADCY4 0.07 0.03 lasso 5 0.03 2.2e-05 6.3 6.8 9.8e-12 0.71 0.08 0.92 TRUE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma ADCY4 0.03 0.01 blup 75 0.03 1.1e-03 4.2 5.3 9.9e-08 0.71 0.05 0.72 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma ADCY4 0.07 0.02 lasso 4 0.03 4.7e-03 4.6 5.4 5.8e-08 0.70 0.03 0.76 FALSE
5 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY4 0.06 0.06 lasso 6 0.09 3.0e-10 5.9 6.7 2.5e-11 0.75 0.08 0.92 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma ADCY4 0.07 0.09 lasso 3 0.08 4.4e-10 4.7 5.9 4.8e-09 0.73 0.78 0.22 FALSE
7 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LTB4R 0.16 0.05 blup 73 0.08 4.9e-04 3.1 -5.2 2.2e-07 -0.70 0.02 0.60 FALSE
8 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R2 0.04 0.04 lasso 1 0.02 2.5e-02 5.7 -5.7 1.3e-08 -0.70 0.04 0.54 FALSE