TWAS hub - LTB4R

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1430	0.0400	1.6e-05	0.123	NA	0.111	NA	0.115	3.0e-10	NA	2.5e-09	NA	1.3e-09
2	GTEx	Artery Aorta	0.2740	0.0850	1.6e-03	0.010	NA	0.030	NA	0.033	8.2e-02	NA	9.1e-03	NA	6.4e-03
3	GTEx	Breast Mammary Tissue	0.2960	0.0710	1.1e-05	0.176	NA	0.097	NA	0.155	2.3e-09	NA	1.1e-05	NA	2.3e-08
4	GTEx	Breast Mammary Tissue (Male)	0.2639	0.1063	1.4e-02	0.065	NA	-0.010	NA	0.030	1.4e-02	NA	6.2e-01	NA	6.7e-02
5	GTEx	Breast Mammary Tissue (Female)	0.1239	0.1075	1.7e-01	0.024	NA	-0.008	NA	0.006	6.3e-02	NA	7.0e-01	NA	2.1e-01
6	GTEx	Cells Transformed fibroblasts	0.1190	0.0400	7.8e-04	0.086	NA	0.028	NA	0.057	5.4e-07	NA	3.6e-03	NA	4.1e-05
7	GTEx	Esophagus Mucosa	0.1740	0.0640	7.9e-04	0.043	NA	0.039	NA	0.038	7.1e-04	NA	1.2e-03	NA	1.4e-03
8	GTEx	Heart Atrial Appendage	0.1700	0.0670	9.9e-03	0.023	NA	0.027	NA	0.063	3.1e-02	NA	2.3e-02	NA	8.6e-04
9	GTEx	Lung	0.1868	0.0483	3.3e-07	0.147	NA	0.095	NA	0.120	2.6e-11	NA	9.8e-08	NA	2.0e-09
10	GTEx	Nerve Tibial	0.1394	0.0432	1.5e-04	0.118	NA	0.104	NA	0.116	1.1e-08	NA	8.7e-08	NA	1.5e-08
11	GTEx	Testis	0.4150	0.0780	5.0e-08	0.271	NA	0.240	NA	0.273	2.0e-12	NA	5.1e-11	NA	1.5e-12
12	GTEx	Thyroid	0.3000	0.0590	2.4e-09	0.179	NA	0.146	NA	0.166	1.0e-13	NA	2.7e-11	NA	1.0e-12
13	METSIM	Adipose	0.1530	0.0374	1.2e-09	0.066	0.072	0.050	0.070	0.047	3.7e-10	6.2e-11	4.7e-08	9.6e-11	1.5e-07
14	YFS	Blood	0.0158	0.0065	2.1e-03	0.004	0.005	0.001	0.004	0.004	1.6e-02	6.1e-03	9.3e-02	1.3e-02	1.2e-02
15	TCGA	Pheochromocytoma and Paraganglioma	0.1650	0.0830	4.8e-03	0.049	0.078	0.043	NA	0.063	5.2e-03	4.9e-04	8.0e-03	NA	1.7e-03
16	TCGA	Stomach Adenocarcinoma	0.0410	0.0230	7.6e-03	0.011	0.012	-0.002	NA	0.004	5.1e-02	4.2e-02	5.1e-01	NA	1.5e-01
17	TCGA	Thyroid Carcinoma	0.0750	0.0320	6.9e-05	0.054	0.036	0.037	NA	0.048	5.6e-06	1.9e-04	1.6e-04	NA	1.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Comparative height size at age 10	8.8	48.3	72.0	-7.8	-5.5	-7.7	-6.4	-6.5	-6.1	-3.6	-7.4	-8.5	-6.4	-7.3	-7.8	-6.4	-7.3	-8.0	-6.8	-7.2
Number of self-reported non-cancer illnesses	6.8	11.8	16.9	-3.7	-4.1	-3.7	-3.6	-4.0	-3.5	-1.9	-2.6	-3.8	-3.9	-3.7	-3.7	-3.7	-2.4	-3.1	-2.4	-3.4
Height	6.1	117.4	222.0	-12.0	-7.7	-11.5	-8.8	-8.7	-9.1	-2.4	-11.7	-13.6	-10.2	-11.1	-11.9	-8.7	-12.4	-14.9	-12.9	-10.5
Relative age of first facial hair	5.9	12.1	22.0	4.0	2.5	4.2	2.9	3.8	2.9	3.6	3.6	4.4	3.3	3.7	3.9	4.7	2.8	2.6	2.4	2.7
Mouth/teeth dental problems: Mouth ulcers	5.3	8.5	12.8	3.5	2.6	3.4	3.3	3.6	2.6	2.4	2.6	3.5	3.1	3.2	3.5	1.9	2.3	2.1	1.9	3.2
Migraine (self-reported)	4.9	6.1	8.6	-2.8	-2.3	-2.8	-2.6	-2.0	-2.5	-1.8	-2.7	-2.8	-2.9	-2.8	-2.7	-2.1	-2.2	-2.4	-2.1	-2.2
Standing height	4.8	47.7	82.1	-7.7	-4.0	-7.6	-5.1	-5.6	-5.3	-1.2	-8.2	-8.5	-6.4	-6.8	-7.5	-6.0	-8.5	-9.1	-8.2	-7.2
Ever used hormone-replacement therapy (HRT)	4.6	5.9	12.1	-2.2	-2.5	-2.3	-2.8	-2.7	-2.7	-0.4	-1.7	-2.5	-2.5	-2.6	-2.3	-1.4	-3.5	-2.5	-2.8	-2.3
Gout (self-reported)	4.3	5.9	10.2	-3.1	-1.3	-2.7	-2.6	-2.6	-2.1	-0.3	-2.5	-3.2	-2.9	-2.8	-3.2	-2.5	-1.6	-1.8	-0.6	-2.8
Medication: Blood pressure	4.3	7.6	11.3	-3.2	-2.0	-3.3	-2.2	-3.4	-2.7	-0.4	-3.3	-3.3	-2.8	-3.1	-3.2	-2.8	-1.3	-2.6	-2.1	-3.3
Heel bone mineral density (BMD) T-score, automated (right)	4.2	9.7	21.1	3.2	2.9	3.0	3.0	1.9	3.4	0.3	3.1	3.7	2.9	3.4	3.2	1.9	3.2	4.3	4.6	2.6
Heel bone mineral density (BMD) T-score, automated (left)	4.0	9.0	18.6	3.0	2.6	2.9	3.2	1.7	3.2	1.0	2.8	3.6	2.7	3.2	3.1	1.9	3.4	3.9	4.3	2.5
Tinnitus: Yes, but not now, but have in the past	4.0	4.3	6.2	-2.4	-1.7	-2.4	-2.1	-2.3	-2.0	-1.5	-2.3	-2.5	-2.2	-2.4	-2.4	-1.6	-0.9	-1.6	-1.9	-2.3
Mouth/teeth dental problems: Bleeding gums	4.0	5.2	11.0	2.4	2.1	2.3	2.5	1.8	2.0	1.9	1.6	2.6	2.4	2.3	2.4	2.3	3.3	2.2	1.8	2.1
Trunk fat-free mass	3.8	21.7	34.9	-5.2	-2.4	-5.4	-3.6	-4.0	-3.7	-0.3	-4.6	-5.7	-4.3	-4.6	-5.1	-4.9	-5.0	-5.7	-5.9	-5.3
Trunk predicted mass	3.7	21.1	34.7	-5.2	-2.3	-5.3	-3.6	-3.9	-3.7	-0.1	-4.5	-5.6	-4.2	-4.6	-5.0	-4.8	-4.9	-5.7	-5.9	-5.2
High blood pressure (siblings)	3.7	5.4	8.1	-2.6	-1.8	-2.4	-2.6	-2.0	-2.0	-2.6	-0.9	-2.8	-2.2	-2.7	-2.7	-2.3	-1.7	-2.5	-2.1	-2.8
Whole body fat-free mass	3.6	20.4	32.5	-5.0	-2.3	-5.2	-3.5	-3.8	-3.5	-0.1	-4.3	-5.5	-4.1	-4.4	-5.0	-5.1	-4.9	-5.6	-5.7	-5.1
Whole body water mass	3.6	20.6	33.3	-5.1	-2.4	-5.2	-3.5	-3.8	-3.5	-0.1	-4.3	-5.5	-4.2	-4.5	-5.0	-5.2	-4.9	-5.6	-5.8	-5.1
Heel T-Score	3.5	27.8	68.1	5.1	3.4	5.2	4.6	3.8	4.4	1.6	5.0	6.3	4.1	5.1	5.0	5.8	8.2	6.6	7.8	3.5
Basal metabolic rate	3.5	19.3	30.0	-5.0	-2.4	-5.1	-3.4	-3.8	-3.4	-0.2	-4.1	-5.4	-4.1	-4.3	-4.8	-5.1	-4.6	-5.3	-5.5	-4.9
Medication: Allopurinol	3.4	4.6	7.6	-2.7	-1.4	-2.3	-2.0	-2.2	-1.8	0.4	-2.2	-2.8	-2.3	-2.4	-2.7	-2.7	-1.4	-1.9	-0.8	-2.5
Eye problems/disorders: Cataract	3.4	3.9	7.3	2.1	1.9	2.4	1.5	1.9	2.1	1.6	1.2	2.3	2.1	2.1	2.0	0.3	2.1	2.7	2.6	1.1
Medication: Lisinopril	3.4	4.4	8.2	-2.5	-1.7	-2.5	-1.8	-2.4	-1.8	-0.4	-1.8	-2.9	-1.8	-2.2	-2.5	-1.5	-1.7	-2.2	-2.5	-2.0
Medication for cholesterol, blood pressure or diabetes	3.3	5.4	8.5	2.2	2.2	2.6	1.8	2.9	2.6	0.6	2.9	2.5	2.3	2.5	2.2	2.2	0.8	2.8	2.4	2.8
Arm predicted mass (left)	3.3	16.6	25.2	-4.6	-2.2	-4.8	-3.2	-3.5	-3.2	-0.3	-3.7	-5.0	-3.8	-4.0	-4.5	-4.9	-3.9	-4.7	-5.0	-4.8
Leg fat-free mass (left)	3.2	17.0	27.8	-4.6	-2.3	-4.7	-3.1	-3.5	-3.2	0.0	-3.7	-5.0	-3.7	-4.0	-4.5	-4.9	-4.4	-5.3	-5.2	-4.5
Leg predicted mass (right)	3.2	16.9	27.5	-4.6	-2.2	-4.6	-3.1	-3.5	-3.1	0.1	-3.8	-5.0	-3.7	-4.0	-4.5	-4.8	-4.7	-5.2	-5.2	-4.4
Arm fat-free mass (left)	3.2	16.5	25.3	-4.6	-2.2	-4.8	-3.3	-3.5	-3.2	-0.3	-3.7	-5.0	-3.8	-4.0	-4.5	-4.8	-4.0	-4.7	-5.0	-4.6
Leg predicted mass (left)	3.1	16.7	26.8	-4.6	-2.2	-4.7	-3.1	-3.5	-3.1	0.1	-3.7	-5.0	-3.7	-4.0	-4.5	-4.9	-4.3	-5.2	-5.1	-4.5
Medication: Omeprazole	3.1	3.7	8.4	-1.7	-2.6	-1.6	-1.8	-1.9	-2.3	-1.2	-1.9	-1.8	-2.0	-2.1	-1.7	-1.0	-0.8	-2.9	-2.4	-2.0
Leg fat-free mass (right)	3.1	16.8	27.7	-4.6	-2.2	-4.6	-3.1	-3.5	-3.1	0.2	-3.7	-5.0	-3.6	-4.0	-4.5	-4.8	-4.7	-5.2	-5.3	-4.4
Tinnitus: Yes, now most or all of the time	3.0	3.5	5.8	2.1	1.5	2.2	2.2	1.9	1.7	1.3	1.4	2.1	1.4	1.9	2.0	2.0	2.4	1.7	2.0	1.2
Number of treatments/medications taken	2.9	5.2	7.5	-2.3	-2.6	-2.3	-2.4	-2.4	-2.7	0.1	-1.4	-2.6	-2.6	-2.6	-2.4	-2.2	-0.9	-2.3	-2.2	-2.7
Medication: Ibuprofen	2.9	3.5	6.4	-1.9	-2.5	-2.1	-2.4	-1.8	-2.1	-1.4	-1.3	-1.8	-1.7	-2.0	-2.0	-0.7	-2.0	-1.4	-2.1	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	2.9	3.2	7.0	1.6	1.6	1.5	2.0	1.4	2.2	1.0	0.9	2.0	1.5	2.0	1.6	1.5	1.2	2.6	2.6	1.6
Pain experienced in last month	2.9	4.8	9.3	2.5	3.0	2.3	2.0	1.6	2.5	1.7	1.6	2.5	2.8	2.5	2.4	1.1	0.8	2.6	2.3	1.6
Chest pain or discomfort	2.8	4.1	8.5	-2.4	-1.5	-2.1	-1.8	-1.8	-1.6	0.3	-1.6	-2.9	-1.7	-2.1	-2.5	-2.6	-2.3	-1.8	-2.0	-1.9
Mouth/teeth dental problems	2.7	4.1	6.6	-2.0	-1.1	-2.0	-2.3	-1.3	-2.0	-2.4	-1.3	-2.0	-2.2	-2.1	-1.9	-2.1	-2.6	-2.3	-2.2	-1.8
Arm fat-free mass (right)	2.7	14.0	23.3	-4.1	-1.9	-4.4	-2.8	-3.0	-2.8	0.1	-3.6	-4.5	-3.4	-3.6	-4.0	-4.7	-4.0	-4.5	-4.8	-4.2
Diastolic blood pressure, automated reading	2.6	8.0	13.2	-3.3	-2.7	-3.4	-2.8	-3.1	-2.6	-0.4	-2.3	-3.3	-3.3	-3.1	-3.3	-1.8	-2.6	-2.4	-2.5	-3.6
Major Depression (MDD)	2.5	3.0	5.0	-2.0	-1.1	-2.1	-1.3	-2.0	-1.8	0.1	-1.4	-2.2	-2.0	-2.1	-2.0	-1.5	-1.3	-1.9	-1.4	-2.1
Eye problems/disorders: Diabetes related eye disease	2.5	2.8	5.9	1.9	1.4	2.0	1.7	2.4	1.5	0.2	2.1	1.6	1.4	1.8	1.9	0.0	1.2	1.9	1.4	1.9
Relative age voice broke	2.5	3.7	6.8	2.5	1.5	2.4	1.8	2.0	1.4	1.2	2.4	2.6	1.9	2.1	2.5	2.0	1.8	1.0	0.8	1.7
Arm predicted mass (right)	2.5	12.7	21.1	-3.9	-1.8	-4.2	-2.6	-2.9	-2.6	0.2	-3.3	-4.2	-3.3	-3.4	-3.8	-4.6	-3.8	-4.2	-4.4	-4.2
Average weekly champagne plus white wine intake	2.5	3.4	5.9	-1.8	-1.7	-1.9	-1.7	-1.4	-2.2	-1.5	-2.3	-1.6	-2.4	-2.1	-1.8	-1.5	-0.4	-2.2	-1.6	-2.4
Crohns Disease (2012)	2.4	3.9	10.4	1.8	1.0	2.0	1.3	1.6	1.6	1.6	2.2	2.1	1.5	1.8	1.7	2.2	2.1	3.2	3.0	1.5
Stomach or abdominal pain in last month	2.4	3.0	7.1	-2.0	-2.7	-1.7	-1.6	-1.0	-2.1	-1.4	-0.8	-1.9	-1.7	-2.0	-2.0	-2.2	-0.5	-1.5	-1.2	-1.7
Forced expiratory volume in 1-second (FEV1)	2.4	8.0	21.7	-3.1	-2.0	-3.2	-1.9	-2.5	-2.1	-0.6	-4.7	-3.1	-2.5	-2.7	-3.0	-1.5	-2.5	-4.1	-3.1	-3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.4	2.9	6.9	-1.5	-1.3	-2.1	-1.4	-1.9	-1.4	-0.7	-1.5	-1.8	-1.2	-1.5	-1.4	-1.4	-1.8	-2.6	-2.6	-1.5
Townsend deprivation index at recruitment	2.3	3.2	7.2	-1.8	-2.4	-1.5	-2.7	-1.8	-2.2	-1.2	0.2	-1.6	-1.9	-2.0	-1.9	-1.5	-2.0	-1.2	-1.0	-2.1
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	6.1	-2.3	-0.7	-2.4	-1.3	-1.6	-1.3	-0.8	-2.2	-2.5	-1.3	-1.9	-2.2	-2.2	-0.6	-0.5	-0.6	-1.7
Weight	2.3	11.4	18.9	-3.9	-2.1	-4.0	-2.6	-3.1	-2.6	-0.2	-2.8	-4.3	-3.1	-3.3	-3.8	-4.3	-3.3	-3.6	-3.8	-4.0
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.3	21.1	-2.8	-1.9	-2.9	-1.8	-2.2	-2.2	-0.7	-4.6	-2.6	-2.3	-2.6	-2.6	-1.5	-2.2	-4.2	-3.4	-2.8
Frequency of tiredness / lethargy in last 2 weeks	2.2	3.6	6.1	-2.1	-2.1	-1.9	-1.7	-2.1	-1.6	-0.6	-2.3	-2.5	-2.0	-2.0	-2.1	-2.4	-0.6	-1.5	-2.0	-1.5
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	5.4	-1.8	-2.3	-2.0	-2.0	-1.8	-1.9	-1.1	-1.1	-1.7	-1.5	-1.8	-1.9	-0.6	-1.6	-1.4	-2.0	-1.4
Pulse wave Arterial Stiffness index	2.2	2.5	5.9	-1.9	-1.3	-1.4	-1.3	-0.5	-1.4	-0.1	-1.8	-2.0	-1.6	-1.6	-1.9	-0.6	-2.4	-2.4	-1.5	-1.4
Commuting to job workplace: Car/motor vehicle	2.2	2.5	6.1	1.7	1.3	1.4	1.3	1.4	1.5	0.1	2.0	1.8	1.9	1.7	1.8	2.0	1.1	1.0	0.9	2.5
Headache pain in last month	2.1	3.7	7.6	-1.9	-2.2	-1.6	-1.2	-1.3	-2.2	0.0	-1.7	-2.4	-2.3	-2.3	-1.9	-2.0	-1.3	-2.3	-2.8	-1.5
Qualifications: CSEs or equivalent	2.0	2.7	4.9	1.9	1.8	1.9	2.0	1.1	1.8	2.2	1.7	1.6	1.6	1.8	1.9	1.5	0.1	0.8	0.7	1.8
Serious illness, injury or assault to yourself	2.0	2.5	4.4	-1.9	-1.2	-1.7	-1.8	-1.9	-1.4	-0.7	-1.6	-2.1	-1.6	-1.8	-2.0	-1.8	-1.0	-1.2	-0.5	-1.4
Sitting height	2.0	13.9	25.0	-4.0	-1.9	-4.1	-2.7	-3.3	-2.8	0.3	-4.7	-4.3	-3.3	-3.5	-3.9	-2.3	-5.0	-4.8	-5.0	-3.9
Medication for pain relief, constipation, heartburn	2.0	3.4	7.2	2.0	2.7	2.1	1.8	1.9	2.0	0.6	0.9	2.0	2.1	2.0	2.0	1.7	1.1	1.7	2.1	1.8
Schizophrenia vs Biploar Disorder	1.9	2.5	4.8	2.0	0.9	2.2	1.4	1.8	1.6	0.4	1.6	1.9	1.6	1.9	2.0	1.3	0.3	1.4	0.8	2.0
LDL Cholesterol	1.9	3.0	6.0	2.1	0.9	2.1	1.2	1.5	0.9	1.2	2.3	2.4	1.7	1.7	2.1	2.3	1.8	1.4	0.5	1.6
Waist circumference	1.9	6.9	11.9	-3.2	-2.2	-3.2	-2.4	-2.8	-2.2	0.2	-1.7	-3.4	-2.6	-2.7	-3.2	-3.4	-1.8	-2.0	-2.1	-3.4
Smoking status: Current	1.9	3.0	5.4	-1.8	-1.8	-1.8	-1.8	-1.4	-2.0	-2.1	-1.6	-1.5	-2.0	-1.9	-1.8	-0.1	-1.2	-1.3	-1.8	-2.3
Miserableness	1.9	3.3	6.4	-2.0	-2.0	-2.0	-1.9	-1.7	-1.8	-1.2	-2.1	-2.1	-2.1	-2.1	-2.1	-1.7	-0.3	-0.9	-0.6	-2.5
Systolic Blood Pressure	1.8	9.1	25.2	-3.8	-2.7	-3.8	-2.1	-3.5	-2.9	-0.9	-2.3	-3.5	-3.5	-3.6	-3.7	-1.6	-1.2	-2.2	-1.5	-5.0
High blood pressure	1.8	5.0	9.9	-2.6	-2.0	-2.5	-1.8	-3.0	-2.0	-0.6	-1.5	-2.7	-2.1	-2.5	-2.6	-2.3	-1.2	-2.4	-1.5	-3.2
Peak expiratory flow (PEF)	1.8	4.2	11.8	-2.4	-1.4	-2.5	-1.1	-2.4	-1.5	-0.5	-3.4	-2.2	-1.8	-2.0	-2.3	-1.7	-1.1	-2.6	-1.9	-2.4
Medication: Blood pressure	1.8	3.4	7.2	-2.0	-2.0	-1.7	-2.0	-1.9	-2.0	-0.4	-0.5	-2.0	-1.7	-2.1	-2.0	-1.2	-1.9	-2.0	-1.7	-2.7
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.4	-1.4	-1.8	-1.3	-1.5	-1.2	-1.8	-1.3	-1.4	-1.5	-1.4	-1.6	-1.4	-1.2	-0.6	-2.1	-1.7	-1.6
Current tobacco smoking	1.7	2.9	5.7	-1.8	-1.7	-1.8	-1.7	-1.3	-1.8	-2.0	-1.5	-1.6	-2.0	-1.9	-1.8	-0.3	-1.1	-1.3	-1.6	-2.4
Chronic bronchitis/emphysema (mother)	1.7	2.0	6.9	-1.7	-1.5	-1.6	-1.4	-1.5	-1.3	-2.6	-1.1	-1.6	-1.8	-1.5	-1.7	-0.6	0.3	0.0	0.6	-0.8
Illnesses of siblings: Diabetes	1.7	2.1	3.7	-1.7	-1.6	-1.5	-1.2	-1.9	-1.4	-0.5	-1.9	-1.7	-1.8	-1.7	-1.8	-0.1	-0.2	-1.1	-0.6	-1.6
Long-standing illness, disability or infirmity	1.7	2.6	8.0	-1.6	-2.6	-1.3	-1.3	-0.9	-1.5	-0.2	-0.6	-1.8	-1.5	-1.6	-1.6	-2.8	0.1	-2.0	-1.6	-1.3
Vascular/heart problems diagnosed by doctor	1.7	4.7	9.4	2.5	2.2	2.4	1.9	3.0	1.9	0.8	1.4	2.6	2.0	2.4	2.5	2.2	1.1	2.2	1.1	3.1
Age when periods started (menarche)	1.6	3.8	6.2	1.7	2.3	1.9	2.3	1.7	2.5	1.6	1.4	2.1	2.0	2.5	1.7	1.1	1.5	1.9	2.3	2.1
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	5.2	-1.5	-0.7	-1.8	-1.9	-1.3	-1.3	-0.4	-1.1	-1.2	-1.5	-1.4	-1.4	-1.4	-2.3	-0.8	-1.0	-1.1
Forced vital capacity (FVC)	1.6	6.3	18.0	-2.8	-1.6	-3.0	-1.5	-2.1	-1.6	-0.3	-4.2	-2.8	-2.3	-2.4	-2.7	-0.9	-2.3	-3.6	-2.5	-3.0
Forced vital capacity (FVC), Best measure	1.6	6.0	17.6	-2.6	-1.8	-2.8	-1.5	-1.9	-1.9	-0.8	-4.2	-2.3	-2.2	-2.3	-2.4	-1.0	-1.6	-3.9	-3.0	-2.8
Number of full brothers	1.6	2.0	2.9	-1.7	-1.6	-1.3	-1.5	-1.3	-1.7	-0.2	-0.9	-1.6	-1.4	-1.6	-1.6	-1.4	-1.2	-1.7	-1.3	-1.2
Hypertension (Self-reported)	1.6	4.6	8.4	-2.5	-1.8	-2.4	-1.7	-2.6	-1.8	-0.6	-1.5	-2.7	-2.0	-2.3	-2.5	-2.4	-1.4	-2.4	-1.4	-2.9
Unable to work because of sickness or disability	1.6	2.0	3.6	-1.2	-1.8	-1.1	-1.7	-0.8	-1.6	-0.6	-1.4	-1.6	-1.7	-1.6	-1.2	-1.3	-1.9	-1.2	-1.9	-0.5
Lung FEV1/FVC ratio	1.5	7.8	13.3	-2.7	-2.6	-3.0	-2.8	-3.0	-3.1	-2.5	-3.6	-2.9	-2.7	-3.0	-2.6	-2.3	-2.3	-3.3	-2.9	-1.9
Ever depressed for a whole week	1.5	1.8	5.2	-1.6	-1.0	-1.7	-1.4	-0.6	-1.8	-0.7	-0.7	-1.6	-1.3	-1.8	-1.6	-0.5	-0.9	-0.8	-1.3	-2.3
Breast Cancer	1.4	3.4	5.2	1.7	2.2	1.9	1.9	1.7	2.1	2.0	1.1	1.8	2.3	2.1	1.6	2.2	1.7	1.6	1.6	1.4
HDL Cholesterol	1.4	2.3	3.3	1.5	1.5	1.7	1.8	1.6	1.7	1.1	1.3	1.4	1.6	1.8	1.6	1.1	1.5	1.5	1.0	1.7
Medication: Simvastatin	1.4	2.1	4.5	-1.6	-1.3	-1.9	-1.0	-1.7	-1.4	-1.0	-2.1	-1.4	-1.2	-1.5	-1.5	-1.4	-0.0	-1.3	-0.9	-2.0
Depression (self-reported)	1.4	1.7	2.8	-1.6	-1.3	-1.5	-0.7	-1.7	-1.2	-0.1	-1.2	-1.5	-1.5	-1.3	-1.6	-1.6	-0.0	-1.4	-1.0	-1.2
Leg pain on walking	1.4	1.8	4.3	0.8	1.3	1.1	1.6	1.0	1.7	1.1	1.6	0.9	0.9	1.3	0.8	1.2	1.4	1.8	2.1	1.1
Supplements: Calcium	1.4	1.5	3.5	-1.4	-0.8	-1.4	-1.4	-1.0	-1.1	-0.4	-0.5	-1.7	-1.6	-1.4	-1.4	-1.9	-0.8	-1.1	-0.7	-1.5
Heart disease (siblings)	1.4	1.7	3.2	1.4	1.3	1.3	1.4	0.9	1.3	1.4	0.7	1.4	1.6	1.4	1.4	1.8	1.6	0.9	1.2	1.1
Bipolar Disorder (2018)	1.3	2.1	3.2	-1.7	-1.1	-1.8	-0.7	-1.5	-1.4	-1.4	-1.0	-1.8	-1.4	-1.6	-1.6	-1.1	-1.3	-1.4	-1.7	-1.5
Crohns Disease (2017)	1.3	2.9	7.3	1.5	1.0	1.7	0.9	1.9	1.8	2.0	0.8	1.8	1.4	1.7	1.4	1.0	1.7	2.6	2.7	2.0
Bipolar Disorder (2011)	1.3	1.2	2.7	-1.2	-1.6	-1.4	-0.7	-1.6	-1.1	0.0	-1.0	-1.0	-1.5	-1.2	-1.1	-0.1	0.7	-1.0	-0.4	-1.4
Nervous feelings	1.3	2.4	4.1	1.3	1.8	1.6	1.1	1.3	1.8	1.1	2.0	1.2	1.9	1.6	1.2	0.1	1.9	2.0	2.0	1.2
Had other major operations	1.3	1.6	4.7	-1.0	-0.7	-1.2	-0.9	-1.9	-0.8	1.3	-1.8	-1.4	-0.8	-0.9	-1.1	-0.2	-2.2	-0.9	-2.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.6	7.6	-1.7	0.2	-1.8	-0.6	-1.2	-0.7	-1.6	-2.8	-1.7	-1.4	-1.2	-1.7	-1.2	-1.3	-2.5	-2.1	-1.6
HbA1C	1.2	1.3	2.6	-1.4	-1.1	-1.6	-1.3	-1.2	-1.3	-0.8	-1.5	-0.9	-1.6	-1.3	-1.3	-0.7	-0.4	-0.3	0.0	-1.2
Cardiovascular Disease	1.2	4.0	8.5	-2.0	-2.0	-2.2	-1.3	-2.1	-1.7	-1.3	-1.0	-2.3	-1.5	-2.1	-2.0	-2.9	-0.9	-2.5	-2.0	-2.8
Hand grip strength (left)	1.2	3.2	10.3	-1.7	-1.1	-1.9	-0.7	-1.6	-1.7	-0.9	-2.2	-1.9	-1.9	-1.7	-1.6	-1.6	-1.0	-2.5	-3.2	-1.5
Trunk fat mass	1.2	5.0	11.8	-2.7	-1.6	-2.7	-1.5	-2.2	-1.5	0.0	-1.8	-3.0	-2.1	-2.2	-2.6	-3.4	-1.9	-1.9	-1.8	-2.8
Hip circumference	1.2	5.3	11.9	-2.8	-1.5	-2.8	-1.9	-2.1	-1.9	0.1	-1.6	-2.9	-2.4	-2.4	-2.7	-3.1	-1.7	-1.8	-1.9	-3.4
Medication: Cholesterol lowering	1.2	1.9	3.8	-0.9	-1.6	-1.4	-1.3	-2.0	-1.6	-0.4	-1.9	-1.1	-1.4	-1.2	-0.9	-1.4	-0.4	-1.9	-1.6	-1.3
Breastfed as a baby	1.2	1.5	3.5	1.4	0.5	1.7	1.1	1.4	0.8	0.5	0.7	1.6	1.5	1.2	1.5	1.4	0.9	0.9	0.6	1.9
Hair/balding pattern: Pattern 4	1.2	2.9	5.9	2.2	0.6	2.1	1.5	1.8	1.4	0.9	1.7	1.9	1.9	1.8	2.2	2.4	-0.4	0.2	-0.5	2.4
Number of children fathered	1.2	1.3	2.6	1.4	1.4	1.2	0.8	1.4	1.3	-0.2	1.0	1.2	0.8	1.3	1.4	0.8	0.7	1.6	1.1	1.0
Commuting to job workplace: Public transport	1.2	1.5	2.9	-1.3	-0.8	-1.1	-1.2	-1.2	-1.4	-0.5	-0.9	-1.4	-1.0	-1.4	-1.3	-1.5	-1.2	-1.0	-1.1	-1.7
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	4.0	1.5	0.9	1.8	0.6	2.0	1.3	1.5	1.1	1.2	1.1	1.2	1.4	0.6	1.0	0.9	0.9	0.7
Systolic blood pressure, automated reading	1.1	3.1	8.3	-2.1	-2.1	-2.1	-1.5	-2.2	-1.8	-1.0	-0.8	-1.9	-2.4	-2.1	-2.1	-0.5	-0.0	-0.7	-0.3	-2.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	7.6	-0.9	-0.6	-1.0	-1.0	-1.7	-0.8	-0.9	-0.7	-1.0	-0.7	-1.0	-0.9	-0.4	-2.8	-1.1	-0.9	-0.5
Illnesses of mother	1.1	1.4	3.6	1.1	1.9	0.8	1.3	0.9	1.2	-1.0	0.8	1.0	1.2	1.4	1.1	-0.3	0.1	1.5	0.7	1.8
Illnesses of father: High blood pressure	1.1	1.4	2.8	-1.2	0.1	-1.1	-1.7	-1.3	-0.8	0.4	-1.1	-1.4	-1.2	-1.0	-1.3	-0.5	-1.6	-1.4	-1.5	-1.2
Depressed Affect (Nagel 2018)	1.0	2.1	6.1	-1.5	-1.3	-1.8	-1.6	-1.4	-1.4	-1.0	-1.6	-1.3	-1.5	-1.5	-1.5	-2.5	-0.1	-0.7	-0.7	-1.5
Smoking Status	1.0	2.4	5.2	-1.7	-1.5	-1.7	-1.7	-1.6	-2.3	-0.3	-0.2	-1.3	-1.9	-1.9	-1.7	-0.6	-1.3	-0.8	-1.8	-2.2
Supplements: Glucosamine	1.0	1.3	3.0	-1.1	-1.5	-1.1	-1.0	-1.0	-1.1	-0.2	-0.7	-1.1	-1.4	-1.1	-1.1	-0.1	0.5	-1.7	-1.7	-1.6
Medication: Atenolol	1.0	1.2	3.2	-1.2	-1.4	-1.0	-0.8	-0.7	-1.4	0.0	-1.6	-0.8	-1.3	-1.5	-1.2	-0.5	0.1	-1.2	-0.5	-1.8
Diabetes (self-reported)	1.0	1.6	5.8	-1.1	-1.5	-0.9	-1.5	-0.2	-1.4	-1.7	-0.6	-1.0	-1.6	-1.2	-1.2	-2.4	-0.8	-1.1	-1.1	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.2	2.8	-1.5	-0.3	-1.3	-1.5	-1.4	-0.5	-0.3	-1.1	-1.1	-1.1	-0.9	-1.6	-1.7	-1.4	-0.2	0.3	-0.8
Age at first live birth	1.0	1.8	4.5	1.3	2.1	1.0	1.9	1.0	0.9	1.7	0.4	1.5	1.1	1.2	1.4	0.8	2.1	1.2	0.9	0.7
Eye problems/disorders: None of the above	1.0	1.1	1.9	-1.2	-0.7	-1.2	-1.2	-1.2	-1.4	0.4	-0.7	-1.1	-1.3	-1.3	-1.1	0.6	-1.3	-1.0	-1.1	-0.6
Had major operations	1.0	1.2	3.4	0.5	1.5	0.9	0.9	0.8	1.8	1.8	0.4	0.2	1.1	1.2	0.5	0.5	-0.1	0.8	1.5	1.4
Diabetes diagnosed by doctor	1.0	1.6	6.2	-0.9	-1.5	-0.9	-1.7	-0.4	-1.3	-1.8	-0.2	-1.0	-1.4	-1.1	-1.0	-2.5	-0.9	-0.9	-1.2	-0.7
Medication for cholesterol	1.0	1.4	4.6	1.1	1.1	1.1	0.8	1.1	0.8	-0.2	0.5	1.2	0.8	1.1	1.0	1.2	2.0	2.1	1.5	1.5
Ulcerative Colitis (UC)	0.9	1.6	4.4	-1.5	-1.2	-1.4	-2.1	-0.8	-1.9	1.0	-0.4	-1.2	-1.3	-1.8	-1.6	-0.1	-0.8	-0.7	-0.7	-1.3
Mean Putamen Volume	0.9	1.0	2.7	-0.8	-0.5	-1.3	-1.0	-1.2	-1.3	0.5	-1.0	-0.9	-0.7	-1.1	-0.8	-0.8	-0.7	-0.9	-1.2	-1.7
Triglycerides	0.9	1.4	3.7	1.1	1.2	1.4	0.7	1.2	1.4	1.2	0.9	1.1	1.2	1.3	1.0	0.6	0.7	1.7	1.9	1.1
Ulcerative Colitis	0.9	1.3	2.8	-1.1	-1.0	-1.4	-1.4	-1.1	-1.7	0.5	-0.4	-1.0	-1.1	-1.5	-1.2	0.3	-1.2	-0.4	-1.3	-1.5
Vitamin and mineral supplements	0.9	1.3	6.2	0.8	0.5	0.9	0.5	0.2	0.8	-0.3	0.5	1.1	1.6	1.0	0.8	2.1	0.7	2.5	1.4	0.5
Supplements: Zinc	0.9	1.0	5.0	-0.7	-0.1	-0.4	-0.6	-0.5	-0.8	1.0	-0.6	-1.1	-0.6	-0.9	-0.7	-1.4	-1.2	-2.2	-1.7	-0.2
Taking other prescription medications	0.9	1.5	2.8	-1.4	-0.9	-1.1	-1.1	-1.4	-1.1	1.1	-1.7	-1.5	-1.2	-1.1	-1.4	-1.4	0.1	-1.4	-0.7	-1.1
Time employed in main current job	0.9	1.0	3.6	-1.0	-1.9	-0.9	-0.7	-0.4	-1.6	0.6	-0.5	-0.9	-1.5	-1.4	-0.9	0.1	-0.1	-0.6	-1.0	-0.7
Pulse rate	0.9	1.5	4.4	1.1	1.0	1.2	0.9	1.2	1.4	0.5	1.6	1.6	1.2	1.5	1.0	-0.2	0.3	1.1	2.1	1.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.7	-1.0	-1.6	-1.1	-0.9	-1.5	-1.0	-0.3	-1.6	-0.9	-0.5	-0.9	-0.9	0.1	-0.4	-0.8	-1.4	-1.3
Pulse wave reflection index	0.9	1.0	3.9	-0.8	0.1	-0.9	-0.9	-0.3	-1.0	0.5	-1.7	-1.1	-1.0	-1.1	-0.8	-0.1	-2.0	-1.0	-1.5	-0.5
Pulse wave peak to peak time	0.9	1.0	3.5	1.1	0.9	0.7	0.8	-0.1	0.9	-0.2	1.1	1.2	0.9	1.0	1.1	0.0	1.9	1.6	0.8	0.7
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.2	0.9	1.4	1.0	1.1	0.7	1.0	1.4	0.7	1.0	1.2	1.1	0.8	0.3	1.1	1.5	1.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.9	0.8	0.6	0.9	0.8	1.5	1.1	1.0	0.2	0.9	1.0	1.1	0.8	1.1	1.3	2.0	1.2	0.8
Whole body fat mass	0.9	3.8	10.2	-2.4	-1.5	-2.4	-1.4	-2.0	-1.4	0.1	-1.2	-2.7	-1.9	-1.9	-2.3	-3.2	-1.4	-1.5	-1.5	-2.4
Osteoporosis (self-reported)	0.9	1.1	4.1	-1.1	-0.0	-1.0	-1.3	-1.0	-1.0	-1.2	-0.6	-1.2	-1.0	-1.0	-1.2	-2.0	-1.1	-0.3	-0.3	-0.8
Commuting to job workplace: Cycle	0.9	1.1	5.4	0.8	2.3	1.1	0.7	1.5	1.4	1.7	-0.5	0.6	0.7	1.0	0.7	0.2	0.5	0.0	0.5	0.8
Qualifications: None of the above	0.8	1.7	5.2	-1.4	-2.3	-1.0	-1.7	-1.7	-1.7	-1.5	0.2	-1.5	-1.2	-1.5	-1.4	-0.5	-0.2	-0.1	-0.1	-1.0
Medication: Ramipril	0.8	1.0	2.4	-1.3	-0.5	-1.3	-0.4	-1.3	-0.3	-0.2	-0.9	-1.4	-0.8	-0.8	-1.3	-1.3	-0.7	-0.9	0.2	-1.6
Arm fat mass (right)	0.8	3.4	10.1	-2.2	-1.3	-2.3	-1.4	-2.0	-1.3	-0.2	-0.9	-2.4	-1.7	-1.8	-2.1	-3.2	-1.1	-1.2	-1.5	-2.4
Overall health rating	0.8	1.7	3.5	-1.4	-1.9	-1.0	-1.9	-1.1	-1.4	0.4	-1.1	-1.5	-1.7	-1.5	-1.5	-0.7	0.3	-0.4	-0.8	-1.5
Illnesses of father: None of the above (group 1)	0.8	1.0	2.1	1.0	0.5	1.0	1.3	1.4	0.8	1.2	1.1	1.1	1.5	1.0	1.0	0.2	-0.4	0.9	0.5	1.1
Ever taken oral contraceptive pill	0.8	0.9	4.2	0.8	0.5	0.9	1.0	0.9	0.8	-1.0	0.8	1.0	0.5	0.8	0.8	1.2	2.1	0.4	0.9	0.4
Supplements: Fish oil (including cod liver oil)	0.8	1.1	1.8	1.1	0.9	1.1	1.1	1.3	1.1	1.0	1.2	0.9	0.4	1.1	1.1	0.6	1.4	0.4	1.3	1.0
Bipolar Disorder or Schizophrenia	0.7	1.7	3.7	-1.3	-1.3	-1.6	-0.7	-1.8	-1.2	-1.9	-1.2	-1.3	-1.2	-1.4	-1.2	-0.7	-0.8	-0.3	-1.0	-1.8
Alzheimer’s Disease (in father)	0.7	0.7	2.6	1.1	0.5	0.7	0.7	-0.1	0.8	0.8	0.5	1.1	0.9	1.0	1.1	1.6	0.5	0.3	0.6	1.1
Fasting Glucose	0.7	0.8	1.8	1.3	0.5	1.1	0.7	1.0	0.7	-0.3	1.3	1.2	0.8	0.9	1.3	0.1	-0.1	0.2	0.5	1.3
Fed-up feelings	0.7	1.3	6.3	-1.2	-1.0	-1.4	-0.7	-1.1	-0.6	-0.9	-1.4	-1.2	-1.0	-1.0	-1.2	-2.5	0.2	-0.2	-0.3	-1.1
Past tobacco smoking	0.7	1.3	3.6	1.2	1.9	1.0	1.1	1.1	1.8	-0.8	0.3	0.6	1.2	1.3	1.3	-0.6	0.5	0.4	0.8	1.5
Illnesses of siblings	0.7	1.0	2.7	1.2	0.8	1.1	1.1	1.5	0.7	0.8	0.3	1.3	0.8	1.2	1.3	0.0	0.0	0.4	0.1	1.6
Blood clot in the leg (DVT)	0.7	0.9	3.2	1.1	0.5	1.5	0.2	1.8	0.9	1.2	0.9	0.9	0.7	0.8	1.0	0.5	1.0	0.7	0.7	0.4
Birth weight	0.7	1.5	6.3	-1.2	-0.4	-1.1	-0.9	-0.5	-0.8	0.9	-2.5	-0.9	-1.0	-0.9	-1.2	-0.2	-1.3	-1.8	-1.3	-1.7
Health satisfaction	0.7	0.9	1.6	-1.0	-1.2	-0.8	-1.1	-0.6	-1.0	1.2	-0.4	-1.2	-0.9	-1.0	-1.0	0.3	-1.3	-0.2	-1.2	-0.6
Heart disease (mother)	0.7	0.9	3.9	-1.1	-1.1	-1.2	-0.6	-2.0	-0.4	-0.4	-1.4	-1.1	-0.2	-0.8	-1.0	0.6	-0.4	-0.7	0.2	-1.2
Number of full sisters	0.7	0.9	2.7	0.6	0.8	1.0	0.4	1.0	1.0	1.2	1.4	0.5	0.5	0.7	0.6	0.9	0.1	1.6	1.6	0.3
Loneliness, isolation	0.7	1.0	4.6	-0.8	-1.4	-1.1	-1.0	-1.2	-0.8	-0.6	0.2	-0.8	-0.8	-0.8	-0.9	-2.1	1.1	0.1	-0.0	-1.1
Hearing aid user	0.7	0.8	1.8	-1.3	-1.1	-1.1	-0.7	-1.4	-0.4	0.4	-0.7	-1.3	-0.7	-0.8	-1.3	-0.8	-0.4	-0.5	-0.2	-1.3
Alcohol drinker status: Previous	0.7	0.9	1.9	-1.0	-1.0	-0.8	-1.1	-1.1	-0.8	-0.9	-1.4	-1.0	-0.8	-0.9	-1.1	-0.9	0.7	-0.8	0.0	-0.8
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.1	0.5	1.5	0.5	1.2	0.0	1.1	-0.1	0.5	-0.0	1.0	0.8	0.5	-0.1	0.4	0.6	1.0	1.4
Blood Platelet Count	0.6	7.0	11.8	-2.8	-3.3	-2.7	-3.4	-2.5	-2.9	-2.7	-1.5	-2.7	-2.9	-3.0	-3.0	-2.7	-1.4	-1.2	-0.9	-3.4
Type 2 Diabetes (T2D) (2018)	0.6	1.2	3.4	-1.0	-1.3	-1.0	-1.3	-0.4	-1.2	-1.6	-0.6	-0.9	-1.5	-1.1	-1.0	-1.8	-0.4	-0.5	-0.6	-1.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.9	-0.4	-1.7	0.0	-1.1	-0.2	-0.9	0.7	-0.2	-0.8	-0.8	-0.9	-0.5	-1.3	-1.2	-0.3	-1.0	-0.4
Ever had hysterectomy (womb removed)	0.6	0.7	2.4	-0.5	-0.9	-0.5	-0.3	-1.1	-1.0	0.3	-0.7	-1.1	-0.3	-0.8	-0.5	0.5	-1.1	-1.1	-1.6	0.1
Impedance of leg (right)	0.6	2.8	4.9	1.8	1.0	1.8	1.8	1.9	1.7	-0.8	0.8	1.7	1.4	1.7	1.8	1.9	1.8	2.0	2.2	1.8
Impedance of leg (left)	0.6	3.1	5.2	2.0	0.9	2.0	1.8	1.8	1.7	-0.6	0.7	1.8	1.6	1.8	2.0	2.0	1.5	2.3	2.2	2.1
Number of incorrect matches in round	0.6	1.0	2.0	1.2	0.2	1.3	0.9	1.0	0.9	-0.5	0.9	1.3	0.6	1.1	1.2	0.9	0.9	0.9	0.8	1.4
Financial difficulties in last 2 years	0.6	0.8	2.1	0.3	0.4	0.5	1.3	0.4	1.1	1.1	1.1	0.2	0.6	0.7	0.3	-0.8	1.4	1.1	1.4	0.5
Alcohol intake versus 10 years previously	0.6	0.9	2.4	-1.2	-0.6	-0.9	-1.5	-0.5	-0.6	-0.7	0.1	-1.3	-1.2	-1.1	-1.3	-1.6	-0.5	-0.4	-0.1	-1.0
Happiness	0.6	0.7	2.6	-0.5	-1.2	-0.8	-0.4	-1.0	-1.0	0.9	-0.0	-0.9	-0.2	-0.9	-0.4	-1.1	-0.2	-0.0	-1.6	-0.7
Exposure to tobacco smoke outside home	0.6	0.8	6.2	-0.1	1.7	0.2	0.6	0.1	1.2	2.5	0.2	-0.4	0.8	0.7	-0.1	-0.7	-0.4	0.1	0.6	0.3
Worry too long after embarrassment	0.6	1.0	2.2	-1.3	-0.6	-1.3	-1.5	-1.3	-0.8	-0.1	-1.0	-1.1	-1.2	-1.0	-1.3	-0.7	-0.1	-0.9	-0.6	-0.9
Shortness of breath walking on level ground	0.6	0.8	2.2	-0.8	-0.6	-0.5	-1.0	-0.5	-0.8	0.4	-0.3	-1.0	-1.1	-1.0	-0.8	-0.7	-1.5	-0.9	-0.8	-1.3
Arm fat mass (left)	0.6	2.6	7.9	-1.9	-1.2	-2.1	-1.2	-1.8	-1.1	0.2	-0.9	-2.1	-1.4	-1.5	-1.8	-2.8	-1.0	-1.1	-1.3	-2.1
Wears glasses or contact lenses	0.6	0.6	3.2	-0.5	-0.2	-0.3	-1.0	-0.3	-0.9	0.8	-1.1	-0.3	-0.9	-0.7	-0.6	-0.4	-0.3	-1.8	-0.8	-0.8
Average weekly beer plus cider intake	0.6	0.8	2.1	-0.8	-0.3	-0.9	-1.0	-0.9	-1.1	0.5	-0.6	-1.0	-0.8	-1.0	-0.8	0.3	-0.7	-1.1	-1.4	-1.2
Pack years of smoking	0.6	0.9	2.6	-1.1	-1.0	-0.9	-0.7	-0.8	-0.5	0.0	-0.8	-1.2	-1.6	-1.0	-1.1	-0.7	-0.9	-0.3	0.2	-1.6
Reaction Time	0.5	0.9	3.8	0.1	1.1	0.1	-0.2	-0.1	0.7	-1.1	1.0	0.3	0.4	0.5	0.1	-1.9	0.6	1.4	2.0	0.7
Verbal and Numeric Reasoning (VNR)	0.5	1.3	3.3	-1.0	0.0	-1.1	-1.8	-1.3	-1.3	-0.8	-1.2	-1.2	-0.8	-1.1	-1.1	-1.5	-1.2	-0.6	-1.1	-1.1
Rheumatoid Arthritis	0.5	0.7	3.3	-0.5	-0.2	-1.2	0.3	-1.8	-0.5	0.4	-1.4	-0.6	0.0	-0.6	-0.3	0.3	0.3	-1.6	-0.7	-1.0
Medication for hormone replacement therapy	0.5	0.6	2.3	-0.2	-0.4	-0.6	-0.3	-1.3	-0.3	-0.4	-0.7	-0.4	-0.5	-0.3	-0.2	-0.4	-1.5	-1.4	-1.4	0.1
Medication: Metformin	0.5	0.7	2.0	0.7	0.8	0.5	0.5	0.9	1.0	-1.1	0.5	0.7	0.7	1.0	0.6	-1.1	0.8	1.4	1.0	0.4
Pack years adult smoking proportion	0.5	0.7	2.1	-0.9	-0.8	-0.8	-0.6	-0.4	-0.4	-0.3	-0.9	-1.0	-1.4	-0.8	-0.9	-0.8	-1.0	-0.3	-0.1	-1.4
High blood pressure (mother)	0.5	0.7	2.1	-0.6	-0.5	-0.3	-0.8	-0.7	-1.0	0.6	-0.1	-0.6	-0.9	-1.0	-0.6	0.7	1.0	-1.0	-0.9	-1.5
Pain all over the body in last month	0.5	0.5	1.4	-0.6	-1.0	-0.6	-0.7	0.1	-1.0	-0.5	-1.1	-0.3	-1.2	-0.9	-0.6	0.5	0.2	-0.8	0.0	-0.7
Tense / ‘highly strung’	0.5	0.8	4.9	0.9	-0.2	1.1	-0.0	0.6	0.3	1.2	2.2	1.0	0.9	0.7	0.8	1.0	0.1	-0.2	-0.5	0.7
Wheeze or whistling in the chest in last year	0.5	0.8	2.0	-1.3	-0.8	-1.1	-0.3	-1.1	-0.4	0.7	-0.6	-1.4	-0.6	-1.0	-1.2	-1.0	-0.8	-0.7	0.2	-1.0
Neck or shoulder pain in last month	0.5	0.7	1.8	-0.9	-0.9	-0.8	-0.4	-0.7	-0.8	0.1	-1.1	-1.0	-0.7	-0.9	-0.9	-0.3	1.1	-1.3	-1.2	-0.1
Alcohol intake frequency.	0.5	1.2	6.3	-1.2	-1.1	-0.9	-1.4	-1.0	-0.6	-1.4	-0.4	-1.5	-0.5	-1.0	-1.3	-2.5	0.5	-0.3	0.2	-0.2
Age at last live birth	0.5	0.8	3.3	0.7	1.4	0.5	1.5	0.2	0.6	1.8	0.1	0.7	1.0	0.7	0.8	0.2	0.8	0.7	0.3	0.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	2.6	1.0	1.6	0.8	0.5	0.8	0.7	0.2	0.7	1.2	0.7	0.9	1.0	-0.1	-0.1	0.6	0.4	0.8
Illnesses of father: Heart disease	0.5	0.7	3.8	1.0	0.4	1.1	1.0	0.7	0.8	0.2	0.6	0.9	0.4	0.7	1.1	0.5	2.0	-0.2	0.2	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	2.3	0.9	0.1	0.9	0.6	0.9	0.6	0.6	0.8	0.8	0.4	0.8	0.8	0.3	0.0	0.6	0.4	1.5
Mineral and other dietary supplements	0.5	0.7	2.1	-0.7	-0.9	-0.9	-0.7	-1.1	-0.8	-0.8	-1.0	-0.6	-0.2	-0.8	-0.8	-0.6	-1.5	0.4	-0.6	-0.7
Guilty feelings	0.5	0.7	1.2	-1.0	-0.5	-0.9	-0.9	-0.5	-0.7	0.6	-1.1	-1.0	-0.9	-0.9	-1.0	-0.9	0.2	-1.1	-0.7	-0.9
Mother’s age at death	0.5	0.6	2.7	1.0	-0.5	1.1	0.4	1.3	-0.0	1.7	-0.1	1.0	0.3	0.5	1.0	0.6	0.7	0.2	-0.1	0.3
Financial situation satisfaction	0.5	0.7	2.5	-0.9	-0.1	-1.0	-0.2	-1.4	-0.8	0.2	-0.5	-1.1	-0.9	-0.9	-0.8	-1.6	-0.1	0.0	-0.5	-0.8
Primary Biliary Cirrhosis	0.4	0.6	1.9	0.4	1.4	0.1	0.9	0.3	1.0	0.8	0.7	0.1	1.1	0.7	0.6	-0.0	-1.2	0.6	0.1	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.3	-0.6	-1.1	-1.0	-0.5	-1.1	-0.7	-0.1	-0.6	-0.7	-0.9	-0.7	-0.6	-0.8	0.8	0.2	0.1	-0.6
Severe depression (siblings)	0.4	0.4	2.1	0.6	1.2	0.3	-0.5	0.2	0.4	0.1	0.2	0.8	0.2	0.4	0.5	0.7	-1.5	1.0	0.5	0.5
Alcohol usually taken with meals	0.4	0.6	2.8	-0.3	-0.9	-0.5	-0.3	-0.6	-0.9	-1.2	-0.8	-0.1	-0.5	-0.5	-0.2	0.4	0.5	-1.2	-1.7	0.1
Father’s age at death	0.4	0.5	1.2	-0.6	-0.7	-0.4	-1.0	-0.4	-1.1	-0.8	-0.5	-0.4	-1.0	-0.8	-0.7	-0.1	0.0	-0.7	-1.0	-0.6
Noisy workplace	0.4	0.5	4.5	-0.1	-0.4	0.2	-0.2	0.9	0.0	2.1	0.8	-0.4	-0.1	-0.2	-0.2	-1.0	-0.6	0.6	0.3	-0.1
Mouth/teeth dental problems: Dentures	0.4	0.7	1.7	-0.9	-1.2	-0.8	-0.8	-1.3	-0.5	-0.0	-0.4	-1.2	-1.0	-0.8	-0.9	-0.3	-0.7	-0.8	-0.2	-0.8
Prospective memory result	0.4	0.5	2.0	0.5	0.6	0.7	0.3	0.9	0.6	0.4	1.4	0.3	0.4	0.6	0.4	-1.1	-1.4	0.7	0.5	0.2
Glaucoma (self-reported)	0.4	0.4	1.6	0.6	0.3	0.7	0.9	1.2	0.6	1.0	0.2	0.5	0.8	0.6	0.6	0.8	-0.1	-0.5	-0.4	-0.2
Comparative body size at age 10	0.4	1.0	5.2	1.1	0.7	0.9	1.3	1.5	0.7	0.5	0.2	1.2	0.8	0.9	1.1	0.5	2.3	0.9	0.1	0.5
Emphysema/chronic bronchitis	0.4	0.5	2.4	-0.8	-0.7	-0.4	-0.3	0.1	-0.2	0.8	0.4	-0.9	-0.5	-0.7	-0.8	-0.9	-1.6	-0.2	0.5	-0.4
Angina (self-reported)	0.4	0.5	2.1	-0.5	-0.6	-0.6	0.0	-1.0	0.1	0.2	-1.1	-0.6	-0.4	-0.2	-0.5	-1.5	0.7	0.5	1.1	-0.3
Mean time to correctly identify matches	0.4	0.8	3.8	0.2	0.8	0.3	-0.3	0.0	0.7	-0.3	1.5	0.3	0.5	0.5	0.2	-1.1	-0.1	1.5	2.0	1.0
Leg fat mass (right)	0.4	1.7	6.2	-1.5	-1.3	-1.7	-0.8	-1.1	-1.0	0.2	-0.4	-1.7	-1.2	-1.2	-1.5	-2.5	-0.4	-0.9	-1.3	-1.7
Supplements: Vitamin C	0.4	0.4	1.3	0.5	0.9	0.7	1.1	0.6	0.5	0.7	0.8	0.3	-0.1	0.4	0.5	0.5	0.7	-1.1	-0.1	0.5
Commuting to job workplace: Walk	0.4	0.4	4.8	0.3	0.0	0.5	-0.2	0.4	-0.1	2.2	0.5	0.4	-0.3	0.1	0.2	0.2	-0.5	0.4	0.7	-0.8
Osteoarthritis (self-reported)	0.4	0.5	1.6	-0.7	0.2	-0.7	-0.7	-1.3	-0.1	0.8	-0.6	-1.0	-0.9	-0.4	-0.7	-1.0	-0.7	-0.2	0.1	-0.6
Medication: Gliclazide	0.4	0.5	3.0	0.4	0.2	0.4	-0.0	-0.3	0.0	-0.4	-0.1	0.6	0.3	0.4	0.4	-0.5	1.7	1.1	1.4	0.1
Medication: Bendroflumethiazide	0.4	0.7	2.3	-0.6	-0.9	-0.6	-0.4	-0.4	-0.9	0.6	0.1	-0.5	-0.6	-0.9	-0.6	-0.3	-0.6	-1.4	-1.3	-1.5
Ever smoked	0.4	0.7	1.9	-0.6	-1.4	-0.6	-0.8	-0.4	-1.4	1.0	0.0	0.0	-0.9	-0.9	-0.7	1.1	-0.1	-0.1	-0.6	-1.3
Number of operations (self-reported)	0.4	0.6	2.4	-0.3	0.1	-0.3	-0.2	-0.6	0.3	1.2	-1.4	-0.8	-0.4	-0.0	-0.3	0.0	-1.5	-1.0	-1.2	0.7
Ever had prostate specific antigen (PSA) test	0.4	0.4	5.2	0.1	-0.2	0.2	0.2	-0.1	-0.3	-1.1	0.1	0.4	0.1	0.1	0.1	0.2	2.3	0.2	0.7	0.2
Cholesterol lowering medication	0.4	0.6	2.3	0.7	-0.1	0.7	0.9	0.6	0.6	0.8	1.5	0.9	1.0	0.7	0.7	0.1	1.2	0.4	0.9	0.1
Leg fat mass (left)	0.4	1.6	6.4	-1.5	-1.1	-1.6	-0.7	-1.2	-0.8	0.2	-0.4	-1.7	-1.1	-1.1	-1.4	-2.5	-0.6	-0.8	-1.3	-1.6
Irritable Bowel Disease (IBD)	0.3	0.7	4.6	0.1	-0.1	0.4	-0.5	0.9	0.1	2.1	0.6	0.6	0.2	0.1	0.0	0.9	0.6	1.4	1.4	0.5
Body Mass Index (BMI) (2010)	0.3	0.4	1.1	0.6	0.9	0.5	0.6	0.4	0.7	-0.3	0.7	0.6	1.1	0.7	0.5	-0.4	-0.7	0.1	0.1	0.9
Waist Hip Ratio (WHR)	0.3	1.2	2.7	-1.2	-1.4	-1.1	-1.2	-1.6	-1.1	0.6	-0.8	-1.4	-1.0	-1.1	-1.2	-0.5	-1.1	-0.9	-1.1	-0.6
Hypothyroidism (self reported)	0.3	0.7	5.2	0.2	0.0	-0.0	0.6	-0.1	0.3	2.3	-0.2	-0.1	0.5	0.3	0.2	-1.2	-1.0	-1.1	-1.3	0.5
Angina	0.3	0.4	1.3	-0.4	-0.4	-0.4	0.1	-0.6	0.1	0.6	-0.9	-0.5	-0.2	-0.1	-0.3	-1.1	0.8	0.7	1.1	-0.2
Medication: Co-codamol	0.3	0.4	1.6	0.2	-0.3	0.5	-0.2	0.4	-0.1	1.1	-0.0	-0.2	-0.5	-0.1	0.1	-1.0	-0.8	-1.3	-1.0	0.8
Diabetes (father)	0.3	0.3	1.4	-0.3	-0.7	-0.3	-0.5	-0.5	-0.4	-0.3	-0.6	-0.2	-0.7	-0.4	-0.4	0.6	0.9	-0.3	0.5	-1.2
Diabetes (mother)	0.3	0.4	2.2	-0.2	0.4	-0.3	-0.4	0.2	-0.4	-0.4	-0.9	-0.1	-0.4	-0.2	-0.2	0.1	1.5	1.0	0.9	-0.7
Trunk fat percentage	0.3	1.3	5.4	-1.3	-1.0	-1.4	-0.6	-1.2	-0.5	0.1	-0.6	-1.6	-1.0	-1.0	-1.3	-2.3	-0.7	-0.4	-0.3	-1.4
Hand grip strength (right)	0.3	0.8	3.7	-0.5	0.6	-0.7	0.7	-0.2	-0.2	0.2	-1.3	-0.6	-0.7	-0.4	-0.3	-1.4	0.1	-1.5	-1.9	-0.8
Average weekly fortified wine intake	0.3	0.3	1.1	0.7	0.7	0.7	0.1	0.5	-0.1	0.7	0.6	1.1	0.2	0.5	0.8	0.8	0.0	-0.2	-0.2	0.5
Maternal smoking around birth	0.3	0.4	1.7	-0.5	-1.3	-0.8	-0.6	-0.7	-0.7	-1.0	-0.1	-0.4	-0.4	-0.6	-0.5	0.7	-0.3	-0.7	-0.6	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	2.4	0.2	-0.2	0.1	0.4	-0.5	0.8	0.4	0.5	0.2	0.1	0.4	0.1	-0.3	1.3	1.4	1.6	0.4
Medication: Levothyroxine sodium	0.3	0.5	2.2	-0.1	-0.4	-0.5	0.1	0.0	-0.1	1.5	0.5	-0.4	-0.1	-0.1	-0.1	-1.0	-1.0	-0.9	-1.3	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.3	1.4	-0.6	-0.6	-0.6	-0.9	-0.4	-0.3	-1.2	-0.2	-0.6	-0.7	-0.4	-0.6	-0.3	-0.7	0.2	0.3	-0.2
Had menopause	0.3	0.3	1.0	-0.9	-0.1	-0.6	-0.3	-0.6	-0.6	0.2	0.0	-0.8	-0.4	-0.7	-0.8	0.0	-0.3	0.5	0.6	-1.0
Heart attack	0.3	0.3	1.0	-0.6	-0.6	-0.6	-0.3	-1.0	-0.3	-0.4	-0.8	-0.7	-0.4	-0.5	-0.6	-0.6	-0.6	-0.2	0.2	-0.8
Fluid intelligence score	0.3	0.6	1.7	-0.8	0.6	-0.9	-1.0	-1.0	-0.4	-1.0	-1.1	-0.9	-0.4	-0.6	-0.8	-1.3	-0.1	-0.2	-0.6	-0.6
Hair/balding pattern: Pattern 3	0.3	0.4	1.6	-0.6	-0.3	-0.7	-0.5	-1.2	-0.3	-0.8	-0.4	-0.9	-0.3	-0.5	-0.6	-1.2	-0.1	-0.3	0.2	-0.5
Number of live births	0.3	0.4	0.7	0.7	0.8	0.6	0.7	0.5	0.7	0.6	0.5	0.3	0.8	0.7	0.7	-0.1	0.1	0.7	0.3	0.8
Medication: Lansoprazole	0.3	0.4	1.7	0.3	1.3	-0.2	0.3	-0.6	0.6	0.5	0.8	0.0	0.7	0.5	0.4	0.2	-0.9	-0.4	-0.5	0.4
Lung cancer (father)	0.3	0.3	1.3	0.2	-0.7	-0.1	-0.0	-0.0	-0.3	-1.0	1.2	0.1	-0.3	-0.2	0.2	-0.9	-0.7	-0.4	-1.1	0.0
Length of working week for main job	0.3	0.3	1.0	0.2	-1.0	0.3	-0.6	0.4	-0.7	-0.8	0.3	0.4	-0.2	-0.3	0.1	0.2	-0.3	-1.0	-0.8	0.3
Exposure to tobacco smoke at home	0.3	0.3	2.1	-0.3	-0.5	-0.2	-1.4	-0.4	-0.4	0.4	0.2	-0.4	-0.2	-0.5	-0.4	-1.0	-0.4	0.2	-0.3	0.2
Birth weight of first child	0.3	0.6	3.6	-1.0	-0.1	-1.3	-0.2	-0.6	-0.4	0.0	-0.7	-0.9	-0.7	-0.6	-0.9	0.2	0.7	-0.6	-0.3	-1.9
Loud music exposure frequency	0.3	0.3	1.6	0.0	0.4	0.4	-0.2	0.7	0.5	0.6	1.3	0.1	-0.1	0.1	-0.0	0.2	0.8	0.6	1.2	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	4.0	0.3	0.2	0.0	0.5	0.0	0.4	2.0	0.4	0.0	0.4	0.4	0.4	-1.2	-1.0	-0.9	-1.1	0.6
Qualifications: College or University degree	0.3	0.9	2.7	-0.7	1.6	-0.7	-0.8	-0.1	-0.5	-1.5	-1.6	-0.7	-0.7	-0.6	-0.7	-1.2	-0.7	-0.6	-1.0	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.5	-0.4	-0.5	-0.8	0.4	-0.8	-0.1	0.1	-0.5	-0.4	-0.1	-0.1	-0.2	-1.0	-0.1	-1.2	-1.2	0.1
Smoking status: Previous	0.3	0.5	4.4	-0.2	-0.6	0.0	-0.1	-0.3	-0.6	2.1	0.9	0.2	-0.1	-0.2	-0.3	0.6	0.1	0.8	0.7	-0.3
Back pain experienced in last month	0.3	0.5	2.2	-0.7	-0.7	-0.7	0.4	-0.7	-0.4	1.0	-0.3	-0.6	-0.9	-0.5	-0.6	0.3	0.5	-1.5	-0.9	0.1
Medication: Aspirin	0.3	0.4	1.3	-0.2	-0.9	-0.4	-0.2	-1.0	-0.9	-0.0	1.1	-0.2	-0.6	-0.5	-0.2	-0.4	0.8	0.2	-0.4	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	4.9	-0.1	0.3	-0.2	0.5	-0.5	0.2	1.4	-2.2	-0.0	0.0	0.1	-0.0	0.7	0.4	-0.3	0.8	0.0
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.1	0.6	0.2	0.4	1.0	0.4	0.4	1.1	0.3	0.4	1.0	0.5	0.7	0.1	1.0	0.6	-0.0	0.6
High cholesterol (Self-reported)	0.3	0.5	2.8	-0.1	-1.7	-0.6	0.0	-0.8	-0.9	0.1	-0.4	0.1	-0.1	-0.3	0.1	-0.6	1.0	-1.4	-0.6	-0.6
Basal cell carcinoma (self-reported)	0.3	0.3	1.4	-0.6	0.4	-0.7	-0.4	-0.3	-0.3	-0.8	-0.3	-0.7	-0.6	-0.6	-0.6	-0.5	-1.2	-0.1	0.2	-0.1
Impedance of whole body	0.3	1.7	3.7	1.4	0.8	1.6	1.5	1.5	1.4	0.3	0.1	1.2	1.1	1.4	1.4	1.9	0.5	1.2	1.9	1.6
Depression (Nagel 2018)	0.2	0.3	1.5	-0.1	-0.4	-0.2	-0.1	-0.0	-0.0	-0.3	0.4	-0.0	-0.4	-0.1	-0.1	-0.9	0.9	1.2	1.0	0.3
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.6	-0.9	0.1	-1.0	-0.7	-1.3	-0.1	-0.2	-1.2	-0.8	-0.3	-0.5	-0.8	-1.6	-0.5	0.3	0.6	-0.4
Neuroticism (Nagel 2018)	0.2	0.4	2.3	-0.6	-0.7	-0.8	-0.8	-0.5	-0.5	0.1	-0.3	-0.5	-0.5	-0.6	-0.6	-1.5	0.2	-0.7	-0.7	-0.4
Schizophrenia (2018)	0.2	0.4	1.6	-0.4	-0.6	-0.5	-0.3	-0.9	-0.4	-1.3	-0.8	-0.2	-0.4	-0.5	-0.3	-0.1	-0.1	0.8	0.1	-1.0
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	-0.0	0.5	0.3	0.4	0.6	0.5	0.9	-0.7	0.0	0.5	0.2	-0.0	-0.4	-0.9	-0.3	-0.3	0.2
Ovarian Cancer	0.2	0.3	0.9	0.5	-0.6	0.4	-0.1	0.6	-0.2	-0.7	0.9	0.7	0.4	0.2	0.5	0.6	0.9	0.1	-0.6	-0.2
Prostate Cancer	0.2	0.3	2.6	0.2	0.4	0.0	0.2	-0.4	0.6	0.5	-0.2	-0.1	0.3	0.4	0.2	-0.1	-1.6	-0.7	-0.6	0.8
Age at First Birth	0.2	0.3	3.1	-0.2	0.4	-0.2	0.1	-0.2	-0.2	0.2	-1.8	-0.1	0.5	-0.0	-0.1	0.6	-0.3	-0.5	-1.0	0.0
Coronary Artery Disease (CAD)	0.2	0.2	2.2	0.1	-0.2	0.4	-0.0	0.9	-0.0	0.1	-0.7	0.1	-0.1	0.0	0.2	1.5	0.2	-0.1	-0.0	0.2
Lupus	0.2	0.3	1.4	-0.0	-0.0	-0.2	0.3	-0.1	-0.2	0.8	0.2	-0.7	-0.1	-0.3	0.0	-1.2	-0.8	-0.2	-1.1	-0.6
Neuroticism (2016)	0.2	0.3	1.4	0.1	1.2	0.1	0.3	0.2	0.7	1.0	0.5	0.1	0.7	0.5	0.1	0.3	0.3	0.3	0.8	0.6
Schizophrenia (2014)	0.2	0.4	1.7	-0.4	-0.2	-0.6	0.1	-1.1	0.1	-1.3	-0.5	-0.2	-0.4	-0.2	-0.3	0.4	-0.3	1.1	0.8	-0.9
Blood Red Count	0.2	1.5	5.6	1.1	0.7	0.8	0.6	-0.0	1.2	-1.1	0.4	1.7	1.2	1.5	1.0	1.0	0.9	1.1	2.1	2.4
Allergy or Eczema	0.2	0.6	1.3	0.8	0.7	1.1	0.6	0.7	1.1	0.6	0.3	0.5	1.0	0.8	0.7	0.2	1.0	0.5	1.1	0.6
Lung FVC	0.2	1.2	3.4	-1.3	-1.6	-1.3	-0.3	-1.3	-0.8	0.3	-1.8	-0.8	-1.0	-1.0	-1.2	0.4	0.4	-1.3	-0.0	-1.5
Neuroticism	0.2	0.6	2.6	-0.8	-0.6	-1.0	-0.9	-0.9	-0.3	0.5	-0.6	-0.9	-0.5	-0.6	-0.9	-1.6	-0.6	-0.6	-0.1	-0.5
Sensitivity / hurt feelings	0.2	0.3	1.8	-0.0	1.1	-0.2	0.2	0.1	0.5	1.3	0.4	0.2	0.3	0.3	-0.0	-0.4	0.4	-0.9	-0.2	0.1
Multivitamins +/- minerals	0.2	0.3	1.3	-0.1	0.3	0.0	0.2	0.4	0.4	0.8	0.5	-0.2	-0.5	0.0	-0.1	-1.1	-0.6	-1.0	-0.1	0.4
Hearing difficulty/problems with background noise	0.2	0.3	1.8	0.1	0.4	0.2	0.8	-0.0	0.6	-1.1	-0.3	-0.2	0.3	0.2	0.0	0.9	1.4	0.3	0.5	0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.0	-0.4	-0.1	-0.3	-0.0	-0.2	0.6	-0.7	-0.3	-0.6	-0.1	0.0	-0.4	0.1	0.4	0.5	1.0	0.1
Neuroticism score	0.2	0.5	1.6	-0.7	-0.3	-0.7	-0.6	-0.9	0.1	-0.1	-0.2	-0.6	-0.5	-0.4	-0.7	-1.3	1.0	0.1	0.9	-0.8
Arm fat percentage (right)	0.2	0.8	3.9	-0.9	-0.7	-1.0	-0.6	-1.1	-0.4	0.1	0.4	-1.1	-0.7	-0.7	-0.9	-2.0	0.4	0.4	0.1	-1.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.0	0.4	0.5	0.2	0.7	0.0	0.7	0.7	1.0	0.2	0.4	0.4	0.4	-0.3	0.4	0.8	0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.0	0.0	0.3	0.0	0.5	0.4	0.1	1.0	-0.8	0.0	0.2	0.1	0.1	-0.8	0.3	-0.3	0.5	-0.0
Body fat percentage	0.2	0.7	4.0	-0.9	-0.9	-1.0	-0.5	-0.9	-0.4	0.2	0.1	-1.2	-0.7	-0.7	-0.9	-2.0	-0.1	0.1	-0.0	-1.1
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.4	-0.3	-0.4	-0.1	-0.9	-0.2	0.8	-0.1	-0.6	-0.4	-0.3	-0.4	0.2	-0.5	-0.4	-0.3	-0.2
Pulse rate, automated reading	0.2	0.7	2.8	0.7	0.4	0.8	0.4	0.6	0.7	1.0	0.8	1.0	0.5	0.9	0.6	-1.1	1.0	0.4	1.7	0.9
Suffer from ‘nerves’	0.2	0.3	2.0	0.4	0.5	0.7	0.4	0.2	0.5	1.4	0.9	0.6	0.4	0.5	0.3	0.1	0.6	0.4	0.1	0.3
Knee pain experienced in last month	0.2	0.3	2.2	0.2	0.3	-0.1	0.7	-0.2	0.7	-0.2	0.2	-0.1	0.3	0.5	0.3	-0.2	1.5	0.5	0.7	0.1
Average weekly red wine intake	0.2	0.2	1.7	-0.2	-0.8	-0.0	0.4	-0.4	-0.3	0.3	-0.5	0.3	0.0	-0.2	-0.2	0.5	1.3	0.3	0.5	-0.5
Mood swings	0.2	0.3	1.8	0.1	0.6	0.3	0.3	0.2	0.7	0.4	-0.0	0.2	0.4	0.4	0.1	0.3	0.8	1.0	1.3	0.1
Friendships satisfaction	0.2	0.2	1.3	-0.0	-0.1	-0.2	-0.1	-0.4	-0.0	1.1	0.7	-0.3	0.1	-0.1	-0.0	-0.6	-0.0	1.1	0.4	-0.3
Breast cancer (self-reported)	0.2	0.2	0.7	-0.3	-0.6	-0.1	0.3	0.1	0.3	-0.5	0.8	-0.5	-0.1	-0.1	-0.4	-0.3	-0.0	0.8	0.5	-0.1
Medication: Paracetamol	0.2	0.3	2.0	-0.4	-1.4	-0.2	-0.2	0.2	-0.6	0.1	0.2	-0.6	-0.7	-0.6	-0.4	-0.5	-0.4	-0.7	-0.7	-0.5
Medication: Atorvastatin	0.2	0.2	1.7	0.3	-0.2	0.2	-0.1	-0.4	0.2	1.3	0.8	0.0	-0.3	0.3	0.3	-0.6	-0.5	-0.3	0.3	0.2
Alcohol drinker status: Never	0.2	0.3	2.5	-0.1	-0.2	-0.2	-0.1	-0.6	-0.1	-1.6	-0.2	-0.2	0.4	-0.2	-0.1	-0.7	-0.4	0.0	-0.6	-0.2
Irritability	0.2	0.3	1.8	-0.2	-0.8	-0.6	-0.2	-1.0	-0.1	-0.8	0.4	0.1	-0.0	-0.0	-0.2	-0.5	1.3	0.0	0.4	-0.1
Myopia	0.2	0.3	2.1	0.0	-0.1	0.3	0.5	-0.2	-0.2	1.4	-1.2	-0.0	0.1	-0.1	0.0	0.9	0.5	-0.7	-0.2	-0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.5	-0.5	-0.6	-0.2	-0.9	-0.1	-0.2	-0.8	-0.6	-0.2	-0.4	-0.5	-0.6	-0.6	-0.1	0.3	-0.7
Worry (Nagel 2018)	0.1	0.2	1.3	0.4	0.5	0.4	0.4	0.3	0.4	0.5	1.1	0.3	0.6	0.4	0.4	-0.3	0.4	-0.3	-0.5	0.3
Alzheimer’s Disease (including proxy)	0.1	0.1	0.8	-0.2	-0.2	-0.2	-0.2	-0.3	-0.0	0.1	-0.9	0.0	-0.1	-0.1	-0.2	0.2	-0.6	-0.7	-0.3	0.1
Blood Eosinophil Count	0.1	0.6	1.6	0.6	0.1	0.7	0.4	0.7	0.9	-0.1	1.3	0.4	1.1	0.7	0.5	0.6	0.9	1.0	1.1	0.5
Blood White Count	0.1	1.0	3.5	-1.0	-0.8	-1.0	-1.0	-0.6	-1.2	-0.8	0.3	-1.0	-0.6	-1.2	-1.1	-1.9	-1.1	-0.4	-0.8	-1.2
BMI	0.1	0.6	4.6	-0.7	-0.7	-0.8	-0.3	-0.6	-0.3	0.3	0.6	-0.8	-0.7	-0.5	-0.7	-2.1	0.2	-0.1	-0.3	-1.0
Respiratory disease	0.1	0.3	2.3	-0.4	-0.6	-0.1	-0.7	-0.5	-0.4	0.1	0.4	-0.7	-0.5	-0.5	-0.5	-1.5	-0.7	0.1	0.2	-0.0
Chronotype (morning person)	0.1	0.3	3.5	0.1	0.6	0.1	0.5	0.5	0.0	-0.8	0.1	0.1	-0.4	-0.0	0.1	0.1	1.9	-0.7	0.2	0.2
Hair Pigment	0.1	2.2	3.7	1.8	1.2	1.7	1.4	1.8	1.5	0.4	1.8	1.9	1.6	1.7	1.8	1.2	1.6	0.8	0.7	1.2
Tanning	0.1	1.4	3.5	-1.4	-1.9	-1.3	-0.7	-1.3	-1.5	0.3	-1.4	-1.0	-1.3	-1.4	-1.3	0.6	-0.3	-1.4	-0.0	-0.9
Average weekly spirits intake	0.1	0.2	0.5	0.3	0.3	0.3	0.2	0.2	0.4	-0.6	0.5	0.3	0.4	0.4	0.4	0.7	0.4	-0.1	0.6	0.3
Hearing difficulty/problems: Yes	0.1	0.1	1.1	-0.2	-0.0	-0.2	0.2	-0.1	0.0	0.4	-0.0	-0.5	0.1	-0.2	-0.3	1.0	0.1	-0.6	-0.6	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	-0.3	0.2	-0.0	-0.1	-0.1	0.5	-0.2	-0.4	-0.5	0.1	0.0	-0.4	-0.9	0.6	-0.0	0.7	-0.2
Body mass index (BMI)	0.1	0.4	3.5	-0.5	-0.3	-0.6	-0.2	-0.6	-0.1	0.3	0.9	-0.5	-0.2	-0.2	-0.4	-1.9	0.5	0.6	-0.1	-0.8
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	0.1	0.4	0.4	0.5	0.2	0.1	0.6	0.1	-0.0	0.6	0.1	0.2	-0.3	0.0	-0.1	-0.4	0.5
Allergy	0.1	0.3	1.8	-0.0	-0.1	-0.4	-0.1	-0.5	-0.8	-1.0	0.3	0.1	-0.4	-0.3	0.0	0.4	-0.9	-0.3	-1.3	-0.3
Impedance of arm (right)	0.1	0.3	1.4	0.3	0.0	0.8	0.5	0.7	0.5	0.1	-0.2	-0.1	0.2	0.3	0.2	1.2	-0.4	-0.1	0.9	0.5
Worrier / anxious feelings	0.1	0.2	0.8	-0.4	-0.3	-0.4	-0.1	-0.2	-0.1	-0.6	-0.6	-0.6	-0.3	-0.4	-0.4	-0.9	0.1	-0.5	-0.3	-0.2
Falls in the last year	0.1	0.1	0.4	0.3	-0.1	0.2	0.5	-0.0	0.3	0.3	0.0	0.0	0.1	0.1	0.3	-0.5	0.6	0.6	0.5	0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	3.0	0.0	0.2	-0.2	-0.1	-0.2	-0.0	-1.7	-0.8	0.3	-0.4	-0.1	-0.0	-0.1	-0.1	0.0	0.1	-0.4
Asthma	0.1	0.2	2.3	-0.1	-0.1	0.2	-0.1	-0.2	0.3	-0.0	0.1	-0.2	-0.1	0.1	-0.2	-0.5	0.8	0.8	1.5	0.2
Impedance of arm (left)	0.1	0.5	2.2	0.6	0.2	0.9	0.8	0.8	0.7	0.5	-0.6	0.4	0.5	0.6	0.6	1.5	-0.6	0.1	1.1	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	-0.5	-0.6	-0.4	-0.3	-0.5	-0.3	-0.6	-0.7	-0.6	-0.4	-0.5	-0.5	-0.5	0.2	-0.4	-0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.5	-0.2	-0.0	-0.5	-0.6	-0.6	-0.0	-0.2	-0.4	0.1	-0.6	-0.2	-0.2	-0.1	-0.4	0.1	-0.1	-0.7
Medication: Paracetamol	0.1	0.2	1.0	-0.3	-1.0	-0.0	0.2	0.6	-0.0	0.6	-0.1	-0.5	-0.4	-0.2	-0.3	-0.8	0.1	-0.7	-0.4	-0.1
Medication: Amlodipine	0.1	0.1	0.5	0.0	0.0	-0.3	0.5	-0.2	-0.0	-0.7	0.3	0.3	0.3	0.1	0.1	-0.5	0.4	0.1	0.7	-0.3
Leg fat percentage (right)	0.1	0.4	1.7	-0.0	-0.5	-0.1	0.2	-0.0	0.1	0.4	1.3	-0.0	0.0	0.1	0.0	-1.0	1.2	1.3	0.7	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.6	0.2	-0.3	0.1	0.2	0.8	-0.3	-0.5	-0.0	0.3	0.0	0.0	0.2	0.7	0.6	0.3	-0.0	-0.1
Family relationship satisfaction	0.1	0.1	0.4	-0.2	-0.6	-0.5	-0.1	-0.6	-0.0	-0.5	-0.5	-0.1	-0.0	-0.1	-0.1	-0.2	0.2	0.6	0.2	-0.1
Medication: Aspirin	0.1	0.2	1.3	0.2	-0.3	0.0	0.3	-0.4	-0.3	0.4	1.1	0.1	-0.3	-0.0	0.2	-0.5	0.5	0.4	-0.3	-0.7
Arm fat percentage (left)	0.1	0.4	2.5	-0.5	-0.5	-0.6	-0.2	-0.7	-0.1	0.6	0.5	-0.6	-0.3	-0.3	-0.5	-1.6	0.5	0.8	0.4	-0.8
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.6	-0.2	-0.5	-0.2	-0.1	-0.5	-0.1	-0.2	-0.4	-0.3	0.1	-0.0	-0.2	-0.0	-0.8	-0.4	-0.3	0.4
Ever had bowel cancer screening	0.1	0.1	0.8	0.1	0.5	0.1	-0.3	0.5	0.3	0.5	-0.3	0.2	0.2	0.1	0.0	0.3	-0.9	-0.4	0.2	-0.2
Qualifications: nursing, teaching	0.1	0.2	0.8	0.2	0.9	0.1	0.7	0.5	0.6	-0.1	-0.0	0.5	0.5	0.4	0.2	0.7	0.5	0.1	-0.1	-0.2
Asthma (self-reported)	0.1	0.2	1.4	-0.4	-0.3	-0.1	-0.3	-0.5	0.1	-0.1	-0.2	-0.4	-0.3	-0.1	-0.4	-0.7	0.6	0.4	1.2	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	1.0	0.0	0.1	0.0	-0.1	0.4	-0.1	0.4	0.5	-0.1	0.0	-0.0	-0.0	0.0	-0.6	-1.0	-0.1	-0.3
Leg fat percentage (left)	0.1	0.4	1.8	0.1	-0.5	-0.1	0.2	-0.2	0.2	0.5	1.2	-0.0	0.1	0.2	0.1	-0.9	1.0	1.3	0.6	-0.2
Risk taking	0.1	0.2	1.5	-0.0	-0.5	-0.2	-0.1	-0.2	-0.0	-1.2	-0.3	0.0	-0.5	-0.0	-0.1	-0.2	-0.1	-0.5	-0.5	-0.7
Fractured/broken bones in last 5 years	0.1	0.1	0.9	0.2	0.7	0.0	-0.2	0.2	0.3	-1.0	0.0	0.2	0.2	0.2	0.2	-0.4	0.6	0.3	0.3	0.2
Age started oral contraceptive pill	0.1	0.2	1.0	-0.2	0.1	0.1	-0.1	0.1	0.0	-0.5	0.3	-0.3	0.0	-0.1	-0.3	-0.4	0.6	0.7	1.0	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.1	0.4	-0.1	0.3	0.1	0.2	-0.1	0.4	0.7	-0.1	0.0	0.1	0.1	-0.1	-0.1	0.4	-0.1	0.2	-0.4

Hub : Genes

LTB4R

Models

Trait associations