Best TWAS P=7.14e-10 · Best GWAS P=3.59e-11 conditioned to 3.34e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Prostate | RP11-104H15.8 | 0.54 | 0.01 | enet | 1 | 0.06 | 0.01560 | -6.16 | -6.2 | 7.1e-10 | -0.17 | 0.05 | 0.37 | TRUE |
| 2 | METSIM | Adipose | NEURL4 | 0.06 | 0.00 | blup | 454 | 0.01 | 0.00817 | -0.68 | -5.1 | 2.7e-07 | -0.02 | 0.11 | 0.02 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EFNB3 | 0.06 | 0.03 | lasso | 4 | 0.05 | 0.00001 | -5.56 | 5.3 | 9.3e-08 | 0.19 | 0.73 | 0.20 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SENP3 | 0.07 | 0.04 | enet | 9 | 0.03 | 0.00027 | 1.98 | 5.2 | 2.3e-07 | 0.20 | 0.44 | 0.03 | TRUE |