[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr20:20,407,782-21,919,054

Best TWAS P=7.15e-10 · Best GWAS P=7.57e-11 conditioned to 0.00639

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 5.8 5.1 2.9e-07 0.82 0.02 0.98 FALSE
2 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 6.3 6.1 9.5e-10 0.97 0.01 0.98 FALSE
3 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 5.9 5.2 1.7e-07 0.93 0.07 0.93 FALSE
4 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 4.8 5.8 8.2e-09 0.79 0.70 0.30 FALSE
5 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 4.8 5.5 4.5e-08 0.89 0.06 0.93 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 4.8 5.2 2.0e-07 0.88 0.15 0.85 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 4.8 5.8 5.2e-09 0.88 0.11 0.88 FALSE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 5.8 6.2 7.2e-10 0.78 0.03 0.54 TRUE
9 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 4.9 5.3 9.0e-08 0.80 0.85 0.15 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 4.9 5.2 2.5e-07 0.85 0.14 0.61 FALSE