Best TWAS P=5.07e-09 · Best GWAS P=3.39e-08 conditioned to 0.0446
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | CST7 | 0.15 | 0.00 | lasso | 4 | 0.03 | 7.0e-02 | -4.3 | -5.3 | 1.1e-07 | 0.62 | 0.06 | 0.07 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | PYGB | 0.12 | 0.13 | enet | 13 | 0.14 | 4.2e-08 | 4.4 | -5.4 | 8.3e-08 | 0.28 | 0.35 | 0.51 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ENTPD6 | 0.32 | 0.10 | bslmm | 432 | 0.12 | 1.8e-15 | 3.9 | 5.8 | 5.1e-09 | -0.70 | 0.72 | 0.20 | TRUE |