Best TWAS P=4.02e-18 · Best GWAS P=6.03e-22 conditioned to 4.96e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | EFEMP1 | 0.19 | 0.10 | lasso | 8 | 0.08 | 3.7e-03 | -7.9 | -8.7 | 4e-18 | 0.78 | 0.04 | 0.7 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | EFEMP1 | 0.29 | 0.14 | enet | 37 | 0.19 | 2.2e-24 | -5.9 | -5.8 | 6e-09 | 0.64 | 1.00 | 0.0 | FALSE |