Best TWAS P=1.72e-11 · Best GWAS P=1.83e-12 conditioned to 0.00244
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 6.6 | -6.5 | 6.8e-11 | -0.70 | 0.04 | 0.28 | FALSE |
| 2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 6.6 | 6.7 | 2.0e-11 | 0.80 | 0.07 | 0.55 | FALSE |
| 3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 6.5 | -6.7 | 1.7e-11 | -0.75 | 0.16 | 0.84 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ULK4 | 0.12 | 0.03 | blup | 256 | 0.05 | 1.9e-03 | 2.9 | 5.4 | 5.4e-08 | 0.35 | 0.24 | 0.08 | FALSE |