[Hub]/) : Traits : Leg predicted mass (left) :

chr4:52,683,607-53,472,171

Best TWAS P=8.91e-08 · Best GWAS P=3.35e-08 conditioned to 0.0895

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue DCUN1D4 0.08 0.02 enet 11 0.04 2.4e-03 5.2 5.2 1.5e-07 0.91 0.06 0.85 FALSE
2 GTEx Breast Mammary Tissue (Female) DCUN1D4 0.02 0.03 lasso 1 0.02 8.2e-02 5.2 5.2 2.3e-07 0.99 0.02 0.17 FALSE
3 GTEx Nerve Tibial DCUN1D4 0.10 0.09 lasso 3 0.10 6.8e-08 4.9 5.3 1.2e-07 0.95 0.06 0.94 FALSE
4 GTEx Testis DCUN1D4 0.19 0.17 enet 14 0.16 8.7e-08 5.3 5.3 8.9e-08 0.88 0.05 0.95 TRUE
5 GTEx Thyroid DCUN1D4 0.03 0.05 lasso 1 0.04 2.4e-04 5.2 5.2 2.3e-07 0.99 0.05 0.89 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma LRRC66 0.07 0.03 lasso 3 0.05 8.0e-04 4.6 -5.1 3.0e-07 -0.63 0.03 0.43 FALSE