[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr1:35,908,451-37,494,602

Best TWAS P=3.44e-10 · Best GWAS P=8.93e-11 conditioned to 0.524

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	RP11-268J15.5	0.17	0.14	lasso	2	0.11	2.8e-06	-6.0	-5.7	9.2e-09	0.25	0.04	0.95	FALSE
2	GTEx	Artery Aorta	RP11-268J15.5	0.20	0.14	lasso	4	0.13	1.2e-07	-6.0	-6.3	3.4e-10	0.31	0.04	0.96	TRUE
3	GTEx	Artery Tibial	RP11-268J15.5	0.11	0.10	lasso	3	0.08	4.1e-07	-6.0	-5.6	1.8e-08	0.29	0.05	0.95	FALSE
4	GTEx	Lung	RP11-268J15.5	0.27	0.16	lasso	4	0.15	1.6e-11	-6.0	-5.8	4.8e-09	0.28	0.04	0.96	FALSE
5	GTEx	Lung	SH3D21	0.12	0.02	lasso	1	0.03	2.1e-03	-6.0	6.0	1.7e-09	-0.29	0.04	0.93	FALSE
6	GTEx	Nerve Tibial	RP11-268J15.5	0.18	0.09	lasso	5	0.08	1.5e-06	-6.0	-5.4	5.3e-08	0.25	0.04	0.96	FALSE
7	GTEx	Skin Sun Exposed Lower leg	SH3D21	0.15	0.07	lasso	5	0.08	4.7e-07	5.9	6.1	1.2e-09	-0.37	0.07	0.91	FALSE
8	GTEx	Thyroid	TRAPPC3	0.10	0.08	lasso	3	0.08	7.2e-07	-5.2	5.3	1.3e-07	-0.76	0.28	0.69	FALSE
9	GTEx	Thyroid	RP11-268J15.5	0.13	0.12	lasso	4	0.10	2.7e-08	-6.0	-5.9	4.1e-09	0.29	0.04	0.96	FALSE
10	GTEx	Thyroid	SH3D21	0.14	0.03	lasso	4	0.05	6.6e-05	-6.0	5.3	1.3e-07	-0.27	0.04	0.94	FALSE
11	GTEx	Whole Blood	MAP7D1	0.12	0.09	lasso	3	0.09	8.3e-09	-5.2	-5.3	9.8e-08	0.78	0.74	0.26	TRUE
12	METSIM	Adipose	RP11-268J15.5	0.05	0.06	lasso	3	0.05	4.0e-08	-6.0	-5.6	2.5e-08	0.29	0.04	0.96	FALSE
13	METSIM	Adipose	SH3D21	0.05	0.05	lasso	3	0.04	5.1e-07	-6.0	6.0	2.0e-09	-0.29	0.04	0.96	FALSE
14	NTR	Blood	MAP7D1	0.02	0.03	lasso	3	0.02	3.4e-08	-5.2	-5.2	2.1e-07	0.76	0.26	0.74	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	RP11-268J15.5	0.21	0.16	lasso	5	0.17	4.3e-21	-6.0	-5.5	3.9e-08	0.21	0.02	0.98	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	SH3D21	0.28	0.18	lasso	5	0.19	4.1e-24	-6.0	6.0	2.3e-09	-0.28	0.02	0.98	FALSE
17	YFS	Blood	MAP7D1	0.04	0.03	lasso	7	0.03	8.3e-10	-5.2	-5.3	1.2e-07	0.78	0.76	0.24	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM176B	0.14	0.04	blup	23	0.04	1.8e-03	-6.0	5.3	1.5e-07	-0.34	0.00	0.96	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	MAP7D1	0.06	0.01	blup	33	0.04	1.3e-03	-5.4	-6.2	8.0e-10	0.75	0.02	0.45	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	TRAPPC3	0.07	0.02	blup	38	0.03	5.7e-03	-4.7	-5.3	1.3e-07	0.69	0.05	0.39	FALSE