Best TWAS P=3.89e-08 · Best GWAS P=6.66e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | GSTM1 | 0.51 | 0.05 | blup | 434 | 0.26 | 1.4e-33 | -1.1 | 5.5 | 3.9e-08 | 0.35 | 0.86 | 0.04 | TRUE |
| 2 | YFS | Blood | GNAI3 | 0.43 | 0.44 | lasso | 11 | 0.50 | 2.3e-192 | 5.4 | -5.3 | 9.3e-08 | -0.95 | 0.00 | 1.00 | TRUE |