TWAS
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Genes
Traits
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Traits
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Arm fat percentage (right)
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chr14:93,011,368-94,495,324
Best TWAS P=2.79e-09 · Best GWAS P=5.82e-14 conditioned to 0.00608
93M
93.2M
93.4M
93.6M
93.8M
94M
94.2M
94.4M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
BTBD7
0.02
0.01
blup
72
0.02
6.8e-03
-6.3
5.9
2.8e-09
-0.80
0.01
0.90
TRUE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
C14orf142
0.11
0.04
enet
7
0.05
7.2e-07
4.0
-5.5
3.7e-08
0.22
0.51
0.08
TRUE
1
GTEx
Cells Transformed fibroblasts
BTBD7
0.16
0.01
lasso
8
0.04
3.6e-04
-5.9
5.6
1.9e-08
-0.58
0.10
0.88
FALSE
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
BTBD7
0.11
0.03
blup
72
0.02
8.0e-02
-5.9
5.5
3.9e-08
-0.56
0.03
0.69
FALSE