[Hub]/) : Traits : Arm fat percentage (right) :

chr14:102,544,860-105,211,221

Best TWAS P=3.68e-11 · Best GWAS P=1.44e-11 conditioned to 0.000139

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous KLC1 0.05 0.03 lasso 3 0.03 1.8e-03 4.8 6.2 7.5e-10 -0.02 0.07 0.75 FALSE
2 GTEx Adipose Subcutaneous XRCC3 0.09 0.08 lasso 5 0.07 3.8e-06 5.2 5.5 5.0e-08 -0.03 0.08 0.92 FALSE
3 GTEx Adipose Subcutaneous APOPT1 0.06 0.02 lasso 5 0.02 8.2e-03 5.5 -5.8 5.2e-09 0.03 0.08 0.82 FALSE
4 GTEx Adipose Visceral Omentum KLC1 0.06 0.02 lasso 2 0.00 2.2e-01 -5.2 5.6 2.3e-08 0.00 0.08 0.49 FALSE
5 GTEx Adrenal Gland KLC1 0.15 0.03 lasso 3 0.06 4.6e-03 5.3 6.2 5.1e-10 -0.03 0.06 0.63 FALSE
6 GTEx Artery Aorta KLC1 0.10 0.14 lasso 3 0.14 6.1e-08 -5.1 5.8 8.5e-09 0.00 0.09 0.90 FALSE
7 GTEx Artery Coronary APOPT1 0.19 0.02 lasso 5 0.05 1.2e-02 3.5 -5.3 1.1e-07 0.07 0.07 0.33 FALSE
8 GTEx Artery Tibial ZFYVE21 0.11 0.09 lasso 1 0.08 8.0e-07 -5.2 5.2 2.2e-07 0.00 0.08 0.91 FALSE
9 GTEx Artery Tibial KLC1 0.11 0.08 lasso 3 0.08 1.1e-06 -5.2 5.2 1.7e-07 -0.01 0.09 0.90 FALSE
10 GTEx Artery Tibial TRMT61A 0.07 0.07 lasso 3 0.06 2.4e-05 -5.2 -5.2 2.7e-07 0.03 0.11 0.87 FALSE
11 GTEx Artery Tibial RP11-73M18.8 0.09 0.06 lasso 4 0.09 7.4e-08 5.5 5.1 2.9e-07 -0.04 0.04 0.96 FALSE
12 GTEx Artery Tibial RP11-73M18.6 0.05 0.03 lasso 2 0.02 4.7e-03 5.5 5.6 2.2e-08 -0.04 0.05 0.80 FALSE
13 GTEx Brain Frontal Cortex BA9 APOPT1 0.17 0.07 lasso 3 0.08 4.6e-03 5.5 -6.2 5.9e-10 0.02 0.04 0.80 FALSE
14 GTEx Breast Mammary Tissue KLC1 0.12 0.02 enet 26 0.07 2.9e-04 4.4 6.2 7.0e-10 0.00 0.23 0.74 FALSE
15 GTEx Breast Mammary Tissue (Female) KLC1 0.09 0.00 lasso 2 0.00 2.4e-01 4.8 5.1 3.0e-07 -0.01 0.07 0.29 FALSE
16 GTEx Cells Transformed fibroblasts KLC1 0.16 0.11 enet 17 0.10 3.1e-08 5.5 5.7 1.4e-08 -0.03 0.03 0.97 FALSE
17 GTEx Cells Transformed fibroblasts APOPT1 0.14 0.12 lasso 3 0.10 6.4e-08 -5.2 -5.7 1.0e-08 0.00 0.08 0.91 FALSE
18 GTEx Colon Transverse KLC1 0.16 0.01 lasso 7 0.00 1.9e-01 4.9 5.5 3.1e-08 -0.02 0.07 0.56 FALSE
19 GTEx Colon Transverse BAG5 0.14 0.05 lasso 10 0.02 4.8e-02 5.4 5.4 6.8e-08 -0.06 0.08 0.76 FALSE
20 GTEx Esophagus Mucosa XRCC3 0.12 0.15 lasso 2 0.13 4.4e-09 5.3 5.3 9.3e-08 -0.02 0.04 0.96 FALSE
21 GTEx Esophagus Muscularis KLC1 0.07 0.01 enet 10 0.02 2.6e-02 -5.2 5.4 5.5e-08 -0.04 0.07 0.67 FALSE
22 GTEx Lung MARK3 0.06 0.02 lasso 3 0.01 6.6e-02 -5.1 -5.2 1.6e-07 0.02 0.18 0.61 FALSE
23 GTEx Lung CKB 0.07 0.01 lasso 2 0.01 3.4e-02 -5.2 -5.7 1.5e-08 0.01 0.09 0.75 FALSE
24 GTEx Muscle Skeletal ZFYVE21 0.10 0.05 lasso 2 0.03 3.3e-04 -5.2 5.5 4.5e-08 -0.02 0.09 0.86 FALSE
25 GTEx Muscle Skeletal KLC1 0.11 0.07 lasso 7 0.08 3.3e-08 -5.1 5.8 5.0e-09 -0.02 0.09 0.90 FALSE
26 GTEx Muscle Skeletal APOPT1 0.14 0.21 enet 10 0.22 6.7e-21 -5.1 5.9 2.9e-09 -0.02 0.06 0.94 FALSE
27 GTEx Nerve Tibial XRCC3 0.08 0.06 lasso 3 0.05 3.5e-04 5.5 5.3 1.1e-07 -0.05 0.07 0.93 FALSE
28 GTEx Pituitary MARK3 0.21 0.27 enet 8 0.25 4.9e-07 -5.1 -5.4 7.4e-08 0.02 0.22 0.64 FALSE
29 GTEx Pituitary RP11-73M18.8 0.23 0.17 lasso 2 0.13 3.6e-04 5.5 5.3 1.2e-07 -0.04 0.05 0.68 FALSE
30 GTEx Prostate MARK3 0.18 0.22 enet 11 0.20 8.0e-06 -5.1 -5.3 1.0e-07 0.03 0.20 0.61 FALSE
31 GTEx Prostate RP11-73M18.8 0.15 0.29 lasso 1 0.25 5.2e-07 5.3 5.3 9.5e-08 -0.02 0.05 0.88 FALSE
32 GTEx Skin Not Sun Exposed Suprapubic XRCC3 0.14 0.03 lasso 14 0.03 1.3e-02 5.3 5.2 1.7e-07 -0.02 0.08 0.89 FALSE
33 GTEx Skin Sun Exposed Lower leg MARK3 0.10 0.09 enet 13 0.08 7.5e-07 -5.2 -5.8 6.2e-09 0.02 0.27 0.73 FALSE
34 GTEx Skin Sun Exposed Lower leg KLC1 0.06 0.09 enet 19 0.08 2.2e-07 5.5 5.5 5.0e-08 -0.02 0.04 0.96 FALSE
35 GTEx Spleen KLC1 0.15 0.05 lasso 3 0.03 6.4e-02 5.5 6.2 4.7e-10 -0.03 0.04 0.62 FALSE
36 GTEx Stomach MARK3 0.10 0.09 lasso 2 0.04 4.5e-03 -5.1 -5.2 2.2e-07 0.02 0.16 0.54 FALSE
37 GTEx Testis ZFYVE21 0.11 0.14 lasso 2 0.11 1.4e-05 -5.2 5.2 1.8e-07 0.00 0.09 0.86 FALSE
38 GTEx Testis KLC1 0.17 0.17 lasso 2 0.15 4.4e-07 5.3 5.2 2.3e-07 -0.02 0.08 0.91 FALSE
39 GTEx Thyroid APOPT1 0.11 0.12 lasso 1 0.10 1.9e-08 5.2 -5.2 2.2e-07 0.02 0.13 0.87 FALSE
40 GTEx Whole Blood KLC1 0.16 0.13 lasso 3 0.11 3.6e-10 5.3 5.3 1.3e-07 -0.03 0.04 0.96 FALSE
41 GTEx Whole Blood XRCC3 0.08 0.12 lasso 3 0.10 1.3e-09 5.3 5.1 2.7e-07 -0.02 0.04 0.96 FALSE
42 METSIM Adipose MARK3 0.03 0.02 lasso 6 0.03 6.3e-05 5.2 -6.1 9.7e-10 0.04 0.08 0.91 FALSE
43 METSIM Adipose TDRD9 0.08 0.04 lasso 10 0.06 1.9e-09 4.9 -5.2 2.2e-07 0.03 0.14 0.86 FALSE
44 METSIM Adipose TRAF3 0.04 0.02 enet 7 0.04 4.5e-06 5.5 5.9 4.0e-09 0.79 0.04 0.96 TRUE
45 YFS Blood KLC1 0.01 0.01 blup 389 0.01 1.0e-03 -5.2 5.1 2.8e-07 -0.03 0.08 0.79 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma C14orf153 0.05 0.02 lasso 4 0.02 8.0e-05 -5.1 -5.6 2.3e-08 0.03 0.02 0.98 FALSE
47 The Cancer Genome Atlas Glioblastoma Multiforme C14orf153 0.14 0.01 blup 40 0.03 3.5e-02 -5.1 -6.0 1.4e-09 0.02 0.01 0.38 FALSE
48 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MARK3 0.07 0.03 blup 64 0.06 5.5e-07 -3.8 -5.3 8.8e-08 0.03 0.04 0.95 FALSE
49 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XRCC3 0.03 0.04 enet 3 0.04 6.1e-05 5.3 5.3 1.2e-07 -0.02 0.01 0.99 FALSE
50 The Cancer Genome Atlas Brain Lower Grade Glioma C14orf153 0.04 0.01 blup 38 0.03 6.2e-04 4.8 -6.4 1.5e-10 0.03 0.02 0.76 FALSE
51 The Cancer Genome Atlas Lung Adenocarcinoma C14orf153 0.06 0.02 blup 38 0.04 2.4e-05 -5.1 -6.6 3.7e-11 0.03 0.02 0.92 TRUE
52 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CKB 0.03 0.00 blup 34 0.02 1.4e-03 5.2 -6.5 6.4e-11 0.03 0.02 0.68 FALSE
53 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C14orf153 0.11 0.11 lasso 3 0.10 1.1e-04 -5.4 -5.9 4.6e-09 0.03 0.01 0.95 FALSE
54 The Cancer Genome Atlas Prostate Adenocarcinoma C14orf153 0.09 0.08 blup 38 0.09 6.2e-10 -5.4 -6.4 1.2e-10 0.04 0.01 0.99 FALSE
55 The Cancer Genome Atlas Prostate Adenocarcinoma CKB 0.07 0.09 blup 32 0.10 1.1e-10 5.5 -6.3 3.9e-10 0.02 0.01 0.99 FALSE
56 The Cancer Genome Atlas Stomach Adenocarcinoma C14orf153 0.20 0.05 lasso 2 0.04 8.8e-04 5.5 -5.6 1.9e-08 0.02 0.01 0.86 FALSE
57 The Cancer Genome Atlas Thyroid Carcinoma KLC1 0.04 0.01 blup 82 0.03 5.4e-04 4.9 5.9 3.6e-09 -0.03 0.03 0.81 FALSE