Best TWAS P=2.68e-08 · Best GWAS P=2.38e-30 conditioned to 3.4e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | AP001816.1 | 0.11 | 0.05 | lasso | 7 | 0.04 | 4.2e-03 | 5.1 | -5.4 | 6.0e-08 | -0.12 | 0.31 | 0.05 | TRUE |
| 2 | METSIM | Adipose | SLC39A8 | 0.18 | 0.15 | lasso | 6 | 0.14 | 5.7e-20 | 5.5 | 5.6 | 2.7e-08 | 0.28 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SLC39A8 | 0.07 | 0.05 | lasso | 2 | 0.04 | 5.0e-05 | 5.5 | -5.1 | 3.0e-07 | -0.24 | 0.30 | 0.02 | FALSE |