Best TWAS P=1.12e-13 · Best GWAS P=3.55e-15 conditioned to 9.46e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -4.7 | 5.5 | 3.1e-08 | -0.66 | 0.67 | 0.16 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 4.9 | 7.4 | 1.1e-13 | -0.48 | 0.13 | 0.87 | TRUE |