Best TWAS P=1.42e-09 · Best GWAS P=1.87e-11 conditioned to 0.000532
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | STK33 | 0.18 | 0.18 | lasso | 9 | 0.20 | 3.8e-24 | -5.2 | 6.0 | 1.4e-09 | -0.70 | 0.86 | 0.14 | TRUE |
| 2 | GTEx | Brain Caudate basal ganglia | RP11-152H18.3 | 0.23 | 0.01 | enet | 1 | 0.06 | 1.1e-02 | -5.3 | -5.3 | 9.3e-08 | 0.78 | 0.03 | 0.77 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | STK33 | 0.14 | 0.08 | lasso | 6 | 0.10 | 1.0e-09 | -5.6 | 6.0 | 1.7e-09 | -0.69 | 0.40 | 0.60 | FALSE |