TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat percentage (right)
:
←
→
chr11:7,714,238-9,408,426
Best TWAS P=1.42e-09 · Best GWAS P=1.87e-11 conditioned to 0.000532
7.8M
8M
8.2M
8.4M
8.6M
8.8M
9M
9.2M
9.4M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
STK33
0.18
0.18
lasso
9
0.20
3.8e-24
-5.2
6.0
1.4e-09
-0.70
0.86
0.14
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
STK33
0.14
0.08
lasso
6
0.10
1.0e-09
-5.6
6.0
1.7e-09
-0.69
0.40
0.60
FALSE
2
GTEx
Brain Caudate basal ganglia
RP11-152H18.3
0.23
0.01
enet
1
0.06
1.1e-02
-5.3
-5.3
9.3e-08
0.78
0.03
0.77
FALSE