Hub : Genes

STK33

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1840 0.0360 0.0e+00 0.176 0.157 0.201 0.171 0.203 7.2e-21 1.2e-18 5.2e-24 2.4e-20 3.8e-24
2 METSIM Adipose 0.0734 0.0291 1.5e-03 -0.002 0.017 0.002 0.022 -0.002 9.2e-01 9.9e-04 1.4e-01 2.6e-04 9.1e-01
3 ROSMAP Brain Pre-frontal Cortex 0.0969 0.0267 4.6e-06 0.045 0.069 0.051 0.072 0.046 1.7e-06 3.5e-09 3.3e-07 1.5e-09 1.4e-06
4 TCGA Colon Adenocarcinoma 0.0770 0.0510 9.5e-03 0.023 0.042 0.012 NA 0.034 1.6e-02 1.8e-03 6.3e-02 NA 4.7e-03
5 TCGA Kidney Renal Clear Cell Carcinoma 0.0502 0.0315 6.3e-03 0.026 0.020 0.028 NA 0.030 6.1e-04 2.1e-03 3.6e-04 NA 2.5e-04
6 TCGA Brain Lower Grade Glioma 0.0899 0.0401 1.8e-06 0.041 0.063 0.046 NA 0.022 1.7e-05 1.2e-07 5.8e-06 NA 1.3e-03
7 TCGA Ovarian Serous Cystadenocarcinoma 0.0800 0.0440 3.2e-03 0.005 0.009 -0.002 NA 0.017 1.5e-01 7.5e-02 4.4e-01 NA 2.4e-02
8 TCGA Thyroid Carcinoma 0.1390 0.0510 1.5e-11 0.082 0.097 0.090 NA 0.097 2.2e-08 1.2e-09 4.4e-09 NA 1.0e-09

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 1.0 2.9 0.4 1.5 0.0 -1.2 -0.0 -0.6 -1.7 0.8
Bipolar Disorder or Schizophrenia 0.5 1.1 3.3 0.1 1.8 -0.2 -0.9 1.0 0.1 -1.7 1.1
Depressed Affect (Nagel 2018) 0.7 1.6 4.0 2.0 0.7 -0.3 -0.9 -0.6 -1.8 0.2 1.9
Depression (Nagel 2018) 1.4 2.2 6.6 2.6 1.0 -0.6 -1.1 -0.6 -2.2 -0.2 1.7
Intelligence (Savage-Jansen 2018) 0.3 0.9 3.6 0.3 -1.3 -1.1 -0.1 -1.9 -0.7 -0.3 -0.3
Neuroticism (Nagel 2018) 1.0 2.3 7.9 1.7 0.5 -2.8 0.8 -1.6 -0.1 1.9 0.6
Schizophrenia (2018) 0.3 0.6 1.9 -0.2 1.1 -0.2 -0.1 1.4 0.6 -0.8 0.7
Schizophrenia vs Biploar Disorder 0.2 0.3 1.0 -0.1 -0.5 0.8 -0.0 0.1 -1.0 0.4 0.3
Worry (Nagel 2018) 1.8 3.8 12.1 0.7 -0.5 -3.5 1.9 -2.3 1.2 2.5 -1.1
Alzheimer’s Disease (in mother) 2.1 2.5 5.0 -0.2 0.9 -2.2 1.5 -1.7 1.9 1.9 -1.3
Alzheimer’s Disease (in father) 0.3 0.4 2.0 0.6 0.4 -0.5 -0.3 0.0 -1.4 0.1 0.1
Alzheimer’s Disease (including proxy) 0.6 0.9 2.4 0.5 1.5 -1.2 0.7 -0.6 0.2 1.5 -0.1
Crohns Disease (2017) 0.8 1.8 5.5 0.1 0.4 -1.2 1.4 2.3 1.0 1.9 -0.4
Irritable Bowel Disease (IBD) 1.0 2.3 7.2 -1.1 -0.7 -1.2 2.1 1.4 0.5 2.7 -1.3
Ulcerative Colitis (UC) 2.0 3.7 8.6 -2.2 -1.4 -1.3 2.7 0.5 0.5 2.9 -2.3
Major Depression (MDD) 1.9 2.3 6.9 1.6 1.4 1.4 -2.6 -0.0 -1.0 -0.9 1.9
Reaction Time 1.6 3.1 9.4 1.3 -0.7 -3.1 2.2 0.1 0.9 2.7 -0.8
Verbal and Numeric Reasoning (VNR) 0.6 1.4 4.4 -0.0 -1.4 -2.1 0.5 -1.5 -1.1 1.0 -0.5
Breast Cancer 0.2 0.4 1.0 0.8 0.7 -1.0 -0.1 -0.4 -0.8 0.2 -0.1
Ovarian Cancer 2.4 3.1 9.6 -1.0 0.4 2.4 -2.1 -2.0 -0.1 -3.1 0.4
Prostate Cancer 0.7 1.0 5.0 0.9 -0.2 2.2 -0.9 -1.0 -0.2 -0.4 0.4
Age at First Birth 1.3 1.9 3.9 -1.6 -1.7 -1.4 0.7 -1.5 1.0 -0.1 -2.0
Bipolar Disorder (2011) 3.7 3.6 7.2 2.6 2.0 0.1 -1.9 2.7 -1.0 -0.6 2.4
Body Mass Index (BMI) (2010) 10.9 15.0 24.8 4.2 1.7 3.8 -4.5 2.5 -4.3 -3.8 5.0
Coronary Artery Disease (CAD) 0.8 1.0 2.7 -1.6 0.3 0.4 0.5 -0.2 1.1 0.7 -1.6
Crohns Disease (2012) 0.6 0.9 4.4 0.4 0.7 -0.9 0.3 2.1 0.3 1.1 0.4
Mean Putamen Volume 1.2 1.4 2.7 -1.4 -1.6 0.7 0.4 -0.9 1.6 -0.7 -1.3
Fasting Glucose 0.4 0.5 1.9 -0.1 -0.3 1.4 -0.9 0.5 -0.8 -0.3 0.8
HbA1C 0.5 0.6 2.4 0.3 -0.4 1.5 -0.5 -1.2 0.1 -0.7 -0.2
HDL Cholesterol 0.4 0.6 3.2 0.6 -1.8 -0.0 -0.3 0.1 0.8 -0.5 -0.7
LDL Cholesterol 0.2 0.3 0.9 -0.1 0.7 0.5 0.5 0.4 0.3 1.0 -0.3
Lupus 0.7 1.0 4.0 0.5 -0.0 -2.0 1.2 0.3 0.3 1.4 -0.2
Neuroticism (2016) 0.7 1.0 3.5 -0.3 -0.4 -1.4 0.4 -1.2 -0.4 1.9 -0.3
Primary Biliary Cirrhosis 0.2 0.3 1.2 -0.2 -1.1 0.1 -0.0 0.9 -0.2 0.2 -0.6
Rheumatoid Arthritis 0.3 0.4 1.6 0.2 -0.1 -0.4 1.3 0.3 0.6 0.7 -0.8
Schizophrenia (2014) 0.2 0.5 2.5 0.1 1.6 -0.4 0.0 0.6 -0.1 -0.5 0.7
Triglycerides 0.1 0.2 0.8 -0.9 0.7 0.1 -0.2 -0.3 -0.1 0.6 -0.1
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.7 0.3 -0.7 -0.0 0.1 0.8 -0.5 0.3 0.5
Ulcerative Colitis 1.7 2.4 5.3 -1.3 -1.1 -1.4 2.3 -1.2 0.2 2.2 -1.8
Blood Eosinophil Count 0.9 6.6 11.8 3.0 1.1 3.0 -2.4 2.0 -2.3 -2.7 3.4
Blood Platelet Count 0.9 10.7 46.0 -2.4 -4.0 6.8 -1.7 -2.4 0.0 -3.0 -1.0
Blood Red Count 1.1 10.5 33.9 1.4 -0.4 5.8 -3.3 1.8 -4.4 -2.4 3.1
Blood White Count 0.1 0.6 3.0 0.8 -0.3 1.7 -0.2 0.5 -0.9 0.4 0.2
Heel T-Score 0.9 7.5 31.0 1.9 1.8 -5.6 -0.4 4.0 -0.9 0.9 2.1
BMI 4.6 26.7 51.6 7.2 4.1 2.5 -4.3 6.8 -4.2 -2.8 7.0
Height 0.3 4.9 12.5 0.8 2.6 -3.5 1.9 -0.9 2.9 2.5 -0.6
Waist Hip Ratio (WHR) 1.0 4.5 11.2 3.3 1.6 -2.5 -0.5 2.6 -2.0 0.6 2.3
Systolic Blood Pressure 0.5 2.7 8.2 -2.1 -1.3 -0.8 0.4 1.5 -2.9 2.0 -0.2
Smoking Status 0.4 0.9 2.9 -0.2 0.2 1.3 -0.4 -0.0 1.7 -1.6 0.2
Allergy or Eczema 0.9 2.5 7.4 2.7 0.7 -2.5 0.1 1.2 -0.5 -0.4 2.0
Cardiovascular Disease 0.6 1.8 7.8 -0.9 -0.7 -1.1 1.8 -0.6 0.2 2.8 -0.7
Hypothyroidism (self reported) 0.2 0.4 1.3 0.2 -0.2 0.3 -0.0 -1.1 0.3 -1.1 0.5
Respiratory disease 0.4 0.9 2.7 0.6 -0.3 -1.6 1.2 -0.6 0.7 1.2 -0.5
Type 2 Diabetes (T2D) (2018) 3.3 6.2 17.3 4.2 2.4 0.4 -2.2 1.5 -2.4 -0.9 3.5
Lung FEV1/FVC ratio 1.3 6.6 13.5 0.6 2.3 3.7 -2.3 3.0 -1.5 -2.4 3.4
Lung FVC 0.8 4.2 13.0 -3.6 -2.2 1.0 0.5 -2.6 0.3 -1.7 -2.2
Neuroticism 0.9 2.1 6.0 1.8 -0.3 -2.4 0.4 -2.5 -0.4 1.1 0.6
Chronotype (morning person) 0.2 0.5 1.2 0.2 -0.4 -0.7 1.1 1.1 -0.1 0.5 -0.6
Hair Pigment 0.0 1.4 3.0 -1.5 -1.1 0.5 0.9 0.7 1.4 1.7 -1.0
Tanning 0.1 0.9 2.0 -0.6 -1.2 1.4 -0.3 1.4 0.5 -1.0 -0.5
Hand grip strength (left) 0.4 0.9 3.2 -0.9 -0.5 -0.9 1.1 0.5 1.8 0.5 -0.8
Number of treatments/medications taken 0.3 0.5 3.1 0.1 -0.3 0.7 0.2 -1.7 0.4 -0.2 -0.2
Average weekly spirits intake 0.5 0.6 2.9 -0.2 -0.6 1.1 0.2 1.7 0.2 -0.3 -0.5
Sensitivity / hurt feelings 1.1 1.8 6.2 1.6 -0.8 -1.3 -0.2 -2.5 -1.3 1.0 1.0
Frequency of depressed mood in last 2 weeks 1.0 1.3 2.8 1.7 0.1 -0.3 -1.5 -0.5 -1.4 -1.0 1.5
Hearing difficulty/problems: Yes 1.9 2.8 10.7 -0.1 -0.2 3.3 -2.1 1.5 -0.7 -2.1 0.7
Relative age of first facial hair 3.1 6.3 17.6 -2.7 -1.9 -1.4 2.3 -1.6 4.2 1.9 -2.9
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 2.3 1.5 1.2 -0.2 -0.8 0.5 -0.2 -0.5 1.0
Ever used hormone-replacement therapy (HRT) 0.7 0.8 3.1 1.8 0.8 -0.3 1.1 -1.0 0.3 0.2 0.8
Ever had hysterectomy (womb removed) 2.2 2.5 5.6 0.3 -0.9 1.7 -2.4 -0.0 -1.9 -2.2 1.4
Systolic blood pressure, automated reading 1.1 3.2 13.8 0.0 -1.2 0.7 -1.4 2.3 -3.7 -0.1 1.6
Eye problems/disorders: Diabetes related eye disease 1.3 1.5 3.2 1.8 1.7 -0.5 -1.0 0.7 -1.6 -0.1 1.1
Angina 0.9 1.2 2.0 0.3 -0.4 0.0 -1.4 1.4 -1.4 -1.4 1.4
Medication for hormone replacement therapy 1.3 1.5 3.2 0.2 -0.0 -1.1 1.6 -1.8 0.8 1.5 -1.4
Vitamin and mineral supplements 1.2 1.7 6.8 0.0 0.4 1.1 -1.1 2.6 -1.1 -1.2 1.1
Supplements: Zinc 0.6 0.7 1.7 0.9 -0.6 0.7 -0.1 -0.4 -1.3 -1.1 0.9
Medication: Co-codamol 0.4 0.5 1.6 -0.5 0.7 1.3 -0.9 -0.2 -0.5 -0.5 0.1
Medication: Metformin 2.5 3.5 9.0 2.7 1.1 0.5 -1.7 1.4 -3.0 -0.7 2.3
Diabetes (father) 1.6 2.0 4.6 1.7 1.0 1.4 -1.0 0.6 -2.1 -1.0 1.9
Diabetes (mother) 1.3 1.6 7.1 0.9 1.1 -0.7 -0.6 2.7 -1.1 -0.3 1.2
Severe depression (siblings) 0.5 0.6 1.5 1.1 -0.8 0.5 -0.1 -0.8 -1.2 -0.6 0.5
Pack years adult smoking proportion 0.4 0.5 1.0 -0.3 -0.9 -1.0 0.4 -0.9 0.3 1.0 -0.7
Impedance of leg (right) 0.2 1.1 2.7 -0.9 0.5 -1.4 0.8 -1.6 0.4 0.4 -1.4
Leg fat-free mass (left) 0.7 3.7 11.2 2.5 2.2 -0.1 -0.9 3.3 -0.7 0.5 2.5
Trunk fat percentage 3.1 12.5 27.7 5.3 2.5 1.1 -2.8 4.6 -2.9 -1.7 4.9
Hand grip strength (right) 0.3 0.9 3.2 -0.9 0.8 -0.8 1.1 0.4 1.8 0.4 -0.4
Townsend deprivation index at recruitment 0.5 0.7 2.8 -0.5 -0.6 1.7 -1.1 0.2 -0.8 -0.7 0.1
Current tobacco smoking 0.3 0.6 1.6 0.0 -1.1 0.3 1.1 -1.2 0.6 0.1 -0.4
Average weekly fortified wine intake 0.8 0.9 3.8 -1.2 -2.0 0.0 0.2 -0.3 -0.4 -0.3 -1.4
Maternal smoking around birth 0.4 0.6 1.9 -0.1 0.1 1.4 -0.2 1.1 0.8 -0.7 -0.7
Fed-up feelings 0.2 0.4 2.0 -0.8 -0.3 0.4 -0.1 -1.4 0.2 0.5 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.9 0.8 -0.4 0.5 -1.2 -1.7 -1.5 -1.5 0.8
Relative age voice broke 1.4 2.1 8.2 -1.8 -0.1 0.6 0.8 -1.3 2.9 1.0 -1.3
Taking other prescription medications 1.0 1.6 6.7 0.6 -0.7 1.0 -0.7 -2.6 1.2 -1.4 -0.0
Age when periods started (menarche) 8.9 21.5 40.7 -6.2 -4.6 -0.5 4.8 -3.9 5.6 1.4 -6.4
Bilateral oophorectomy (both ovaries removed) 2.0 2.3 3.3 1.8 1.7 1.4 -1.6 1.2 -0.9 -1.7 1.6
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 10.8 -0.3 1.4 -3.3 0.6 0.9 0.4 1.8 -0.6
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 2.2 1.1 1.1 -0.4 -1.3 0.1 -1.5 -0.5 1.4
Qualifications: CSEs or equivalent 0.7 0.9 3.6 0.2 0.9 1.2 0.4 1.9 0.3 0.9 0.7
Serious illness, injury or assault to yourself 1.5 1.8 8.6 0.3 -1.6 -0.5 -0.7 -2.9 0.0 -1.5 0.1
High blood pressure 1.7 4.7 14.7 -1.6 -2.1 -2.2 2.9 -0.3 -0.1 3.8 -1.7
Hayfever, allergic rhinitis or eczema 1.0 2.1 7.1 2.7 0.7 -1.4 -0.4 1.1 -0.9 -0.8 2.1
Multivitamins +/- minerals 0.6 0.8 3.6 0.7 -0.6 -1.1 0.5 -1.9 0.3 -0.0 -0.2
Stomach or abdominal pain in last month 0.7 0.8 2.0 1.4 1.4 -0.3 -0.8 -0.6 -0.0 -0.4 1.3
Supplements: Glucosamine 1.7 2.2 4.0 2.0 2.0 1.0 -1.5 -0.4 -1.4 -1.2 1.6
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 0.9 0.5 0.7 -0.4 0.4 0.5 0.9 0.0 -0.4
Medication: Atenolol 1.9 2.4 5.4 -1.9 -2.3 0.7 1.6 -0.8 0.9 1.7 -1.6
Medication: Levothyroxine sodium 0.4 0.7 1.7 -0.6 -1.3 0.8 0.4 -1.2 1.0 -0.5 -0.5
Sitting height 0.1 0.6 2.2 0.2 0.7 -1.5 0.4 0.4 0.5 1.2 -0.3
Chronic bronchitis/emphysema (father) 0.6 0.7 3.1 0.4 -1.3 -0.7 0.1 -1.8 0.2 0.0 -0.3
High blood pressure (mother) 0.2 0.3 1.1 0.2 0.6 -0.6 0.3 1.1 -0.5 0.3 0.5
Body mass index (BMI) 3.5 15.0 28.9 5.3 2.4 2.1 -3.1 5.4 -3.5 -1.8 5.3
Impedance of leg (left) 0.3 1.4 3.2 -1.1 0.3 -1.0 1.0 -1.8 1.1 0.2 -1.8
Leg predicted mass (left) 0.7 3.7 11.3 2.6 2.2 -0.2 -0.7 3.4 -0.7 0.7 2.4
Trunk fat mass 3.3 14.4 31.1 5.6 3.1 1.0 -3.0 5.0 -3.0 -1.7 5.2
Waist circumference 3.7 13.6 29.7 5.5 2.6 1.3 -3.1 4.8 -3.1 -1.3 5.2
Number of incorrect matches in round 0.5 0.8 3.3 1.8 -0.1 -1.4 0.2 0.6 -0.7 0.1 0.6
Past tobacco smoking 0.8 1.6 8.5 0.7 0.1 -0.4 -0.1 0.8 -2.9 1.5 0.6
Alcohol usually taken with meals 0.8 1.3 2.3 1.5 0.7 0.4 -1.5 0.7 -1.0 -1.4 1.3
Nervous feelings 1.3 2.4 8.3 0.4 -0.5 -2.9 1.5 -1.4 0.6 2.1 -1.4
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.1 2.6 1.6 -0.4 -1.5 -0.6 -1.5 -0.5 -0.7 0.6
Hearing difficulty/problems with background noise 1.5 2.3 6.0 -0.8 -0.0 2.4 -2.3 0.3 -0.7 -2.4 0.8
Hair/balding pattern: Pattern 2 2.3 2.9 5.3 1.6 2.0 1.6 -2.1 1.0 -0.8 -2.3 1.5
Had menopause 0.4 0.5 1.9 1.4 -0.8 -0.0 0.4 -0.4 -0.1 -0.7 0.8
Had other major operations 1.0 1.3 3.2 0.4 -1.3 1.2 -1.1 -1.1 -0.9 -1.8 0.5
Forced vital capacity (FVC) 0.7 2.5 9.8 -3.1 -0.4 -0.7 1.4 -0.4 1.5 0.3 -2.3
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.5 8.9 -0.3 0.5 -3.0 0.8 0.2 0.2 1.3 -0.6
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.7 0.9 0.5 -0.2 -0.4 -0.8 -0.8 -0.2 1.3
Qualifications: None of the above 0.1 0.2 0.9 0.1 1.0 0.4 -0.2 0.1 -0.4 0.5 0.0
Financial difficulties in last 2 years 0.4 0.5 1.4 0.2 -0.7 0.8 -0.7 -0.9 -0.3 -1.2 0.3
Mouth/teeth dental problems 0.6 0.9 4.8 0.3 0.0 -1.1 0.9 -0.4 -0.6 2.2 -0.3
Heart attack 1.3 1.7 4.2 -1.4 -1.1 -0.6 1.6 -1.2 0.0 2.1 -1.4
Allergy 0.9 2.1 8.5 -2.9 -0.9 1.3 0.6 -0.4 0.4 0.9 -2.1
Pain all over the body in last month 4.6 4.9 8.1 1.6 1.1 2.6 -2.9 2.0 -2.0 -2.8 2.3
Diabetes (self-reported) 3.7 5.7 12.2 3.5 1.6 0.7 -2.3 1.2 -3.4 -1.2 3.2
Hayfever/allergic rhinitis (self-reported) 1.9 2.4 5.7 2.4 1.3 0.4 -1.4 1.2 -1.5 -1.7 1.9
Medication: Ramipril 1.0 1.3 5.2 -0.1 -1.7 0.4 1.4 -2.3 -0.1 0.1 -0.1
Medication: Simvastatin 0.8 1.1 3.1 0.3 -0.9 1.2 -1.7 -0.3 -1.7 -0.7 0.3
Fluid intelligence score 0.5 1.0 2.7 -0.1 -1.4 -1.6 0.4 -1.2 -0.6 0.7 -1.1
Illnesses of siblings 0.6 0.8 2.8 0.1 -0.4 1.7 -1.0 -1.1 -0.5 -1.0 -0.1
Neuroticism score 1.1 2.3 6.5 1.9 -0.2 -2.4 0.7 -2.5 -0.2 1.3 0.3
Weight 2.4 11.9 28.7 4.8 3.0 0.9 -2.4 5.4 -2.4 -0.8 4.7
Impedance of arm (right) 0.5 2.2 8.8 -0.5 -1.3 -1.8 1.3 -3.0 0.5 0.4 -1.1
Arm fat percentage (right) 4.4 17.3 36.6 6.0 2.3 1.4 -3.6 4.8 -4.1 -2.3 6.0
Trunk fat-free mass 0.6 3.5 10.5 2.3 2.3 0.2 -1.0 3.2 -0.7 0.4 2.4
Hip circumference 2.0 8.5 18.8 3.8 1.7 2.2 -2.3 4.3 -2.0 -1.2 4.0
Time employed in main current job 2.5 2.9 7.0 1.0 -0.2 -2.6 2.3 -0.3 1.6 2.6 0.0
Alcohol intake versus 10 years previously 1.4 2.1 4.6 -0.4 0.2 2.1 -2.1 1.0 -1.4 -1.5 1.5
Father’s age at death 3.1 4.1 8.6 2.2 1.8 0.4 -2.1 -0.5 -2.8 -2.0 2.9
Worrier / anxious feelings 1.3 2.4 9.3 0.6 -0.8 -1.9 1.1 -3.0 0.7 1.7 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.0 1.2 -0.5 -1.1 0.6 -1.4 0.4 0.3 0.0
Falls in the last year 1.3 1.7 3.4 0.9 1.5 1.2 -1.7 -0.4 -0.9 -1.5 1.8
Hair/balding pattern: Pattern 3 0.8 1.1 3.3 -0.5 -1.5 -0.1 1.1 1.8 0.0 1.4 0.1
Number of live births 2.1 3.0 6.0 1.6 1.1 1.8 -2.5 -0.2 -1.4 -2.4 1.8
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 8.9 -3.0 -0.4 -0.1 0.7 0.2 0.9 -0.4 -1.5
Pulse rate 0.5 0.9 3.4 -0.5 -1.3 0.3 -1.0 -0.5 -1.9 -0.4 -0.2
Happiness 0.6 0.7 2.8 0.8 -0.5 -1.2 -0.3 -0.4 -1.7 -0.3 0.4
Noisy workplace 0.3 0.4 1.1 -0.6 0.7 0.3 0.8 0.4 0.7 1.1 -0.1
Qualifications: A levels/AS levels or equivalent 0.6 1.3 2.7 -0.9 -1.3 -1.6 -0.2 -1.3 -1.6 -0.8 -0.5
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.1 0.7 0.6 0.7 -0.4 -0.0 0.1 -1.1 0.9
Mouth/teeth dental problems: Dentures 0.3 0.6 1.8 -0.3 0.1 1.3 -1.1 0.5 0.2 -1.1 0.1
Asthma 0.2 0.5 1.1 0.8 -0.5 -1.1 0.8 -0.7 0.3 0.8 0.0
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.9 0.1 -0.3 1.3 -1.1 1.0 0.2 -1.7 -0.4
Medication: Cholesterol lowering 0.2 0.3 0.8 -0.1 -0.8 -0.9 -0.1 -0.6 -0.5 0.7 -0.2
Depression (self-reported) 0.9 1.1 2.8 1.7 1.2 -1.5 0.6 0.3 1.1 0.5 0.3
Medication: Lansoprazole 0.8 0.9 3.1 0.2 1.1 0.1 -1.8 -1.2 0.5 -1.0 0.4
Prospective memory result 0.7 0.9 3.6 -0.0 1.0 -0.0 0.3 0.4 1.9 1.4 -0.5
Lung cancer (father) 1.2 1.4 3.5 0.8 0.9 1.9 -1.8 0.3 -0.4 -1.6 0.3
Illnesses of mother 0.4 0.5 2.2 -0.6 -0.4 1.5 0.0 -0.9 0.0 -0.6 0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.1 4.5 -2.1 0.8 0.1 0.8 0.7 0.9 -0.3 -1.3
Pulse wave Arterial Stiffness index 1.9 2.2 6.3 -1.4 -1.7 -0.7 0.6 -1.6 1.1 1.4 -2.5
Impedance of arm (left) 0.5 2.4 7.8 -1.0 -1.2 -1.7 1.5 -2.8 1.0 0.5 -1.5
Arm fat mass (right) 4.0 16.4 34.0 5.8 2.8 1.3 -3.3 5.3 -3.6 -1.8 5.7
Trunk predicted mass 0.6 3.7 10.9 2.4 2.3 0.1 -1.0 3.3 -0.8 0.4 2.4
Standing height 0.3 3.2 6.9 -0.3 1.7 -2.6 1.7 0.8 2.4 2.3 -1.1
Length of working week for main job 1.1 1.2 2.4 -0.6 -0.1 -1.0 1.3 0.2 1.4 1.3 -1.5
Exposure to tobacco smoke at home 1.1 1.2 2.5 -0.6 0.0 -1.2 1.4 -0.2 1.6 1.0 -1.5
Breastfed as a baby 0.6 0.8 3.0 -1.1 -0.1 -0.3 0.9 -0.9 0.7 -0.0 -1.7
Tense / ‘highly strung’ 1.9 3.2 8.2 0.7 -0.3 -2.9 2.6 -1.1 1.8 2.1 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 4.1 1.4 0.4 -1.0 0.4 -2.0 1.4 -0.4 -0.2
Hair/balding pattern: Pattern 4 1.3 3.1 13.0 0.5 1.6 -3.6 1.8 0.2 -0.2 2.5 0.1
Birth weight of first child 0.5 0.9 1.8 1.2 -0.6 -1.1 0.6 0.9 -1.3 0.9 0.3
Peak expiratory flow (PEF) 0.4 0.8 2.9 -0.7 -0.1 1.4 -0.1 0.9 -0.3 -1.7 0.5
Pulse wave reflection index 1.3 1.6 4.5 -1.4 -0.8 0.2 0.9 -1.0 2.1 1.2 -1.6
Ever highly irritable/argumentative for 2 days 2.7 3.2 5.7 1.6 1.5 2.1 -2.0 -0.6 -1.8 -1.8 2.4
Loud music exposure frequency 0.5 0.6 2.7 0.0 -0.2 -0.9 0.4 0.9 -0.3 1.7 -0.2
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 1.4 -1.2 -0.7 -0.5 -1.1 -0.5 -0.6 -1.1 -0.2
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.2 -0.4 -0.3 -0.5 0.5 0.5 0.8 -0.3 -1.1
Blood clot in the leg (DVT) 0.6 0.7 3.1 1.8 0.7 -0.9 -0.1 -0.5 0.1 0.4 1.0
Medication: Paracetamol 0.3 0.4 1.9 0.3 0.2 1.1 -0.1 0.1 0.4 -1.4 -0.1
Headache pain in last month 0.4 0.7 1.7 -0.5 -0.1 1.3 0.6 -1.2 0.9 0.1 -1.1
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.1 0.6 0.6 1.0 -0.2 0.7 0.9 -1.0 0.4
Glaucoma (self-reported) 1.4 1.7 5.0 2.2 -0.4 -0.3 -0.9 1.3 -1.7 -0.5 1.6
Gout (self-reported) 2.1 2.9 6.0 -1.9 -2.4 -0.3 1.1 -2.2 1.1 0.7 -2.4
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 2.9 -0.4 -0.8 0.4 0.6 -1.7 1.1 -0.6 -0.2
Medication: Amlodipine 0.8 1.1 2.1 -1.1 -1.4 -1.5 0.4 -0.3 -0.7 1.3 -1.0
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.6 1.3 0.6 -0.9 -0.7 0.2 -0.1 0.0 1.0
Birth weight 0.2 0.5 1.0 0.9 0.5 -1.0 0.9 -0.1 -0.3 0.9 0.4
Chronic bronchitis/emphysema (mother) 0.3 0.4 0.7 0.7 0.5 0.5 -0.3 0.7 -0.4 -0.9 -0.8
High blood pressure (siblings) 0.7 1.0 3.7 -0.0 -0.3 -1.9 1.3 -0.1 1.0 1.1 -0.4
Forced vital capacity (FVC), Best measure 0.6 2.1 5.8 -2.4 0.8 -0.9 1.5 0.4 1.7 0.5 -2.0
Body fat percentage 3.9 15.5 32.3 5.7 2.8 1.4 -3.3 4.8 -3.6 -2.1 5.5
Leg fat percentage (right) 6.1 21.9 42.5 6.1 3.3 2.2 -4.2 5.4 -4.9 -2.9 6.5
Arm fat-free mass (right) 0.8 4.1 12.7 2.4 2.8 0.2 -1.1 3.6 -0.4 0.3 2.4
Exposure to tobacco smoke outside home 0.5 0.6 3.7 0.0 -0.2 -0.9 0.4 0.1 1.9 0.2 -0.5
Comparative body size at age 10 2.2 6.0 18.7 2.7 -0.1 0.3 -2.3 1.7 -4.3 -1.3 3.5
Number of full brothers 1.3 1.7 4.0 0.6 1.3 0.7 -2.0 1.1 -1.3 -1.3 1.3
Worry too long after embarrassment 1.2 2.1 7.5 1.5 -0.4 -2.7 0.9 -1.5 0.3 1.8 0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 3.5 0.6 0.7 -0.7 0.1 -1.2 1.9 -0.7 -1.1
Wheeze or whistling in the chest in last year 0.2 0.4 1.5 0.2 0.8 -0.5 0.1 1.2 -0.5 0.7 -0.1
Number of children fathered 6.8 7.7 12.0 2.1 2.2 2.9 -3.5 2.4 -2.6 -3.2 3.0
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 2.1 0.5 -0.2 -1.4 1.3 -0.9 1.5 0.7 -0.8
Age at first live birth 1.1 1.9 6.7 -0.7 -0.8 -2.6 1.6 0.0 1.1 1.5 -1.1
Pulse wave peak to peak time 1.7 2.0 5.8 1.3 1.9 0.3 -0.4 1.6 -1.0 -1.0 2.4
Health satisfaction 5.7 7.3 15.8 3.4 3.0 0.9 -2.9 0.8 -3.3 -1.3 4.0
Shortness of breath walking on level ground 1.4 1.7 4.6 1.3 1.6 -2.2 0.9 0.4 0.8 1.7 0.3
Qualifications: College or University degree 0.4 1.2 3.4 -0.6 -1.8 -1.9 1.0 -0.4 -0.1 0.6 -1.2
Eye problems/disorders: None of the above 1.7 2.0 4.3 -2.1 -1.8 1.4 0.9 -1.5 1.1 -0.3 -1.3
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.4 0.4 0.6 -1.1 1.2 -0.2 0.8 0.4 -0.5
Emphysema/chronic bronchitis 5.5 6.2 12.1 -2.5 -1.8 -2.6 2.7 -2.0 1.6 2.5 -3.5
Medication for pain relief, constipation, heartburn 1.2 2.0 5.8 -0.5 -1.1 -2.2 1.5 -1.0 -0.5 2.4 -0.5
Neck or shoulder pain in last month 0.5 0.7 2.6 -0.5 0.4 0.2 0.4 1.3 1.6 0.3 -0.6
Medication: Blood pressure 0.7 1.2 3.3 -0.4 -0.6 -1.2 0.6 -0.7 -1.8 1.8 -0.1
Angina (self-reported) 0.8 1.1 2.1 -0.1 -0.6 -0.1 -1.4 0.9 -1.5 -1.3 1.3
Migraine (self-reported) 1.4 1.7 3.1 -1.8 -1.1 1.3 -0.4 -1.6 1.2 -1.4 -1.3
Medication: Ibuprofen 1.1 1.4 5.2 0.7 -0.1 1.2 -1.5 0.9 -0.6 -2.3 0.4
Medication: Allopurinol 1.5 2.0 7.6 -1.3 -2.8 0.0 0.8 -1.8 0.5 0.3 -1.4
Medication: Omeprazole 0.7 0.8 4.3 0.2 2.1 -0.2 -0.3 -0.2 0.2 -0.9 1.0
Medication: Seretide 50 evohaler 0.2 0.2 0.6 -0.0 -0.5 -0.8 0.6 -0.4 -0.2 0.3 0.3
Mean time to correctly identify matches 1.2 2.2 7.5 1.1 -1.0 -2.7 1.8 -0.6 0.7 1.9 -0.7
Heart disease (mother) 0.3 0.4 2.2 0.4 -0.3 -1.5 0.2 0.4 -0.1 0.6 -0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.7 2.0 6.8 -0.3 0.6 2.0 -1.7 -0.1 -0.2 -2.6 1.4
Whole body fat mass 3.8 15.9 33.5 5.8 3.2 1.1 -3.1 5.2 -3.4 -1.7 5.6
Leg fat mass (right) 4.1 15.9 30.9 5.5 3.1 1.5 -3.3 5.1 -3.7 -2.0 5.6
Arm predicted mass (right) 0.8 4.3 14.1 2.4 3.0 0.2 -1.0 3.8 -0.2 0.5 2.2
Pulse rate, automated reading 0.9 2.9 8.3 2.3 0.6 0.3 -2.1 0.8 -2.9 -0.9 1.8
Alcohol intake frequency. 0.5 1.1 2.6 0.2 1.6 1.1 -0.9 0.4 -1.2 0.2 1.6
Comparative height size at age 10 0.3 1.7 3.9 1.5 0.9 -1.2 -0.5 1.6 -2.0 0.6 1.5
Number of full sisters 1.4 1.7 5.9 -0.4 -0.2 0.4 1.2 2.3 2.4 0.3 -0.5
Suffer from ‘nerves’ 1.1 1.7 7.0 0.4 -0.7 -2.6 1.2 -0.8 0.2 2.0 -0.7
Overall health rating 1.1 2.3 4.7 2.1 2.1 0.7 -1.5 -0.0 -1.3 -0.6 2.2
Chest pain or discomfort 0.4 0.6 3.0 0.7 -0.1 -0.5 -0.2 -0.8 -1.7 -0.0 0.4
Had major operations 0.5 0.5 1.3 0.7 0.6 -1.1 -0.8 0.2 0.7 -0.9 0.4
Age at last live birth 0.5 0.8 3.2 -0.0 -1.0 -1.8 0.7 0.2 0.2 1.2 -0.3
Family relationship satisfaction 0.5 0.7 1.6 0.4 -1.0 -0.8 0.5 -1.0 -1.3 0.6 0.7
Leg pain on walking 1.9 2.4 6.7 1.9 2.6 0.2 -1.4 0.2 -0.8 -1.4 2.2
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.0 3.5 1.9 0.2 0.1 -0.2 1.4 -0.3 -0.6 1.5
Commuting to job workplace: Car/motor vehicle 0.4 0.5 1.0 1.0 0.5 -0.1 -0.5 0.7 0.8 -0.9 0.5
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 5.4 -0.2 1.2 -0.0 1.1 0.3 0.5 2.3 -0.4
Medication: Aspirin 1.1 1.5 3.6 0.8 -0.0 1.0 -1.9 0.4 -1.5 -1.9 0.7
Supplements: Vitamin C 0.5 0.6 2.5 -0.1 1.0 -0.1 -0.1 0.3 -0.8 1.6 0.6
Knee pain experienced in last month 0.7 1.0 3.0 1.5 0.5 1.0 -0.5 0.3 -1.0 -0.6 1.7
Hypertension (Self-reported) 1.8 5.0 18.8 -1.1 -1.6 -2.3 3.1 -0.5 -0.2 4.3 -1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 2.6 1.6 1.0 -0.2 -0.3 -1.3 -0.1 -0.6 0.8
Illnesses of father: Heart disease 0.3 0.5 1.7 0.5 1.0 -0.2 -0.2 0.6 -0.3 -1.3 0.6
Illnesses of siblings: Diabetes 4.4 5.4 10.8 1.7 2.7 0.1 -2.3 3.3 -2.4 -0.8 3.2
Smoking status: Previous 1.7 2.5 7.7 -0.3 1.0 1.6 -1.5 0.1 2.5 -2.8 0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 2.5 -0.3 1.1 0.5 -0.8 1.6 -0.2 -0.6 0.3
Whole body fat-free mass 0.6 3.7 11.8 2.4 2.3 -0.0 -0.8 3.4 -0.5 0.6 2.4
Leg fat-free mass (right) 0.5 2.8 9.8 2.0 2.0 0.0 -0.5 3.1 0.0 0.6 2.0
Arm fat percentage (left) 4.1 16.2 34.3 5.9 2.4 1.5 -3.4 4.8 -3.8 -2.2 5.8
Average weekly red wine intake 0.6 0.9 3.6 1.1 0.5 -1.4 -0.2 1.9 0.1 -0.1 0.4
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.8 -1.7 0.2 0.0 -0.0 -0.1 0.6 0.2 -1.1
Mood swings 0.2 0.4 1.3 1.2 0.6 -0.1 0.1 -0.5 -0.1 0.6 0.8
Loneliness, isolation 1.1 1.5 5.2 2.3 -0.1 -0.5 -0.8 -0.5 -2.0 0.3 1.2
Long-standing illness, disability or infirmity 1.3 2.0 5.6 2.1 0.9 -0.3 -1.2 0.3 -1.4 -1.2 2.4
Ever had bowel cancer screening 0.3 0.4 1.8 0.1 0.1 0.2 -0.8 -0.1 1.3 -0.7 -0.5
Diabetes diagnosed by doctor 2.7 4.4 9.9 3.1 1.9 -0.3 -1.5 2.0 -3.0 0.0 2.6
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.3 -1.1 -0.4 0.9 0.1 -0.2 0.2 0.8 0.3
Friendships satisfaction 2.9 3.6 7.3 1.2 0.9 0.8 -2.6 -0.9 -2.7 -2.6 1.9
Qualifications: nursing, teaching 0.4 0.7 3.0 0.0 -0.7 0.5 -0.6 -1.0 -0.6 -1.7 0.3
Commuting to job workplace: Walk 1.6 1.7 4.1 -1.1 -1.4 -2.0 1.2 -0.3 -0.6 2.0 -0.8
Eye problems/disorders: Cataract 0.5 0.6 1.9 1.1 1.4 -0.0 -0.2 0.4 -0.0 0.4 1.2
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.4 1.1 -0.3 -0.4 -0.1 -1.3 -0.1 -0.8 1.5
Medication for cholesterol 0.6 1.0 3.0 0.3 1.4 -0.4 -0.6 1.1 0.7 -1.7 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 2.0 0.1 -0.2 -0.5 -0.5 -1.4 -1.0 0.0 0.1
Back pain experienced in last month 0.6 0.9 3.8 1.0 2.0 -0.2 -0.7 0.7 0.5 -0.4 0.9
Mineral and other dietary supplements 0.3 0.4 1.1 0.2 -0.5 -0.4 1.0 0.8 0.4 0.8 -0.0
Breast cancer (self-reported) 1.5 1.8 6.1 -1.8 -2.5 0.1 0.1 -1.7 -0.3 0.5 -1.5
Asthma (self-reported) 0.4 0.8 1.9 0.8 -0.5 -1.4 1.1 -0.9 0.3 1.2 0.0
Osteoporosis (self-reported) 0.8 1.0 2.5 -0.6 -0.1 1.1 1.6 -1.1 1.1 0.8 -0.7
Osteoarthritis (self-reported) 0.3 0.4 1.0 0.7 0.2 0.3 -0.8 -0.4 -0.5 -0.5 1.0
Medication: Aspirin 1.3 1.7 4.1 1.0 0.5 0.9 -2.0 0.2 -1.4 -2.0 1.0
Medication: Gliclazide 2.1 2.4 5.3 1.9 0.3 -0.7 -1.1 2.3 -1.8 -0.9 2.0
Illnesses of father: None of the above (group 1) 0.5 0.6 2.5 -0.6 -0.2 -0.7 0.4 0.0 1.6 0.7 -0.6
Smoking status: Current 0.5 0.8 2.8 0.0 -1.1 -0.3 1.7 -0.8 0.7 0.9 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 10.5 -3.2 -1.0 0.5 1.0 -0.4 0.8 -0.5 -2.7
Whole body water mass 0.7 4.0 12.5 2.5 2.4 -0.0 -0.9 3.5 -0.6 0.5 2.5
Leg predicted mass (right) 0.5 2.8 9.4 2.1 2.0 0.0 -0.6 3.1 -0.1 0.6 2.0
Arm fat mass (left) 3.6 14.7 31.5 5.6 2.7 1.1 -3.0 5.2 -3.3 -1.6 5.4
Number of self-reported non-cancer illnesses 0.4 0.6 1.3 0.4 -1.2 -0.6 0.9 -1.1 0.7 0.4 -0.8
Average weekly champagne plus white wine intake 0.1 0.2 0.7 0.3 -0.8 0.4 0.4 -0.3 0.3 -0.4 -0.5
Miserableness 0.2 0.4 1.1 1.0 0.4 -0.3 -0.8 -0.7 -0.7 0.1 0.6
Guilty feelings 1.3 2.0 7.0 1.1 0.1 -2.4 0.8 -2.6 0.7 0.9 -0.2
Wears glasses or contact lenses 2.0 2.3 6.6 0.6 -0.8 2.2 -2.3 0.5 -0.7 -2.6 0.3
Ever taken oral contraceptive pill 0.3 0.4 2.3 -0.1 0.3 1.5 0.2 0.5 -0.1 -0.1 0.4
Hearing aid user 0.3 0.3 1.5 0.4 -0.1 0.6 0.5 1.2 -0.1 -0.2 0.3
Mother’s age at death 0.2 0.3 0.8 -0.4 -0.9 -0.3 -0.1 0.6 0.2 0.7 -0.3
Financial situation satisfaction 0.4 0.5 2.0 0.7 0.2 -0.4 -0.8 0.2 -1.4 0.1 0.4
Tinnitus: Yes, now most or all of the time 5.9 6.9 13.5 1.6 0.9 3.7 -3.3 0.8 -2.5 -3.4 3.0
Commuting to job workplace: Public transport 0.2 0.2 0.8 -0.0 0.8 0.2 -0.2 0.9 -0.3 -0.1 0.5
Eye problems/disorders: Glaucoma 1.2 1.4 3.8 1.8 -0.9 -0.0 -0.9 1.1 -2.0 -0.5 0.9
Medication: Blood pressure 0.6 1.1 4.8 -0.5 -1.7 0.1 0.8 0.3 -0.4 2.2 -0.4
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.7 0.5 0.1 -0.4 -0.3 0.6 0.8 -0.6 0.2
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.9 0.2 1.0 0.8 -0.7 0.0 -0.4 0.1 0.2
High cholesterol (Self-reported) 0.7 1.2 2.3 0.3 -0.8 1.5 -1.5 0.2 -1.3 -1.2 0.9
Medication: Bendroflumethiazide 0.6 1.0 3.2 0.3 -0.5 -0.9 0.5 1.4 -1.1 1.8 0.2
Medication: Paracetamol 0.4 0.6 1.6 1.2 1.3 0.6 0.1 0.7 0.4 -0.8 0.5
Medication: Lisinopril 0.6 0.7 2.4 0.4 1.1 -0.8 0.2 1.1 -0.1 1.6 0.4
Medication: Atorvastatin 0.6 0.8 2.1 0.5 -0.2 0.2 -0.3 1.4 -1.2 -0.6 1.5
Illnesses of father: High blood pressure 0.8 1.0 3.2 1.3 0.1 0.0 0.9 -0.2 -1.8 0.9 1.2
Alcohol drinker status: Never 0.6 0.7 2.0 -1.4 -0.4 0.2 0.3 -1.3 -0.3 0.6 -1.2
Ever smoked 0.8 1.4 6.9 -0.9 -0.8 0.1 0.5 -0.7 2.6 -1.1 -0.9
Basal metabolic rate 1.0 5.7 16.2 3.1 2.7 0.2 -1.3 4.0 -1.0 0.2 3.1
Leg fat percentage (left) 5.9 21.3 40.6 6.1 3.3 2.6 -4.2 5.3 -4.4 -3.2 6.4
Arm fat-free mass (left) 1.1 5.5 16.0 2.9 2.8 0.4 -1.5 4.0 -1.0 -0.0 2.9
Number of operations (self-reported) 2.1 3.1 6.0 2.3 0.3 0.5 -2.5 -0.3 -1.5 -2.3 2.3
Average weekly beer plus cider intake 2.0 2.9 6.0 -2.4 0.1 -1.3 1.5 -0.8 1.9 2.4 -1.8
Irritability 0.9 1.5 5.6 0.8 2.4 -1.7 1.0 -0.7 0.7 0.7 0.3
Risk taking 0.5 0.8 2.8 -1.7 -0.0 -1.4 0.2 -0.2 1.0 -0.3 -0.8
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.3 -0.4 -1.5 -1.4 0.5 -0.5 0.4 1.2 -0.8
Fractured/broken bones in last 5 years 1.3 1.7 4.3 0.8 -0.2 2.1 -1.6 -1.3 -0.6 -1.9 0.7
Age started oral contraceptive pill 0.3 0.4 1.4 1.2 0.5 -0.6 0.6 -0.2 -0.0 0.8 0.5
Diastolic blood pressure, automated reading 0.6 1.8 6.8 -0.8 -1.7 1.2 -0.7 1.2 -2.6 0.4 0.6
Ever depressed for a whole week 1.2 1.5 7.6 0.9 -0.8 0.4 -0.1 -2.8 -1.5 0.3 0.8
Unable to work because of sickness or disability 2.3 2.9 6.8 1.8 0.4 1.6 -2.6 0.8 -1.7 -1.4 2.2
Commuting to job workplace: Cycle 1.6 1.9 7.4 -2.7 -0.6 -0.7 0.1 1.5 0.7 1.2 -1.7
Myopia 0.3 0.4 1.7 0.0 -0.3 0.3 -0.3 -0.3 1.3 -1.2 -0.4
Vascular/heart problems diagnosed by doctor 1.5 4.1 12.3 1.8 2.2 1.9 -2.6 0.6 0.3 -3.5 1.5
Cholesterol lowering medication 1.0 1.4 3.2 -0.0 -0.9 1.6 -1.6 -0.7 -1.8 -0.9 0.7
Medication: Omeprazole (e.g. Zanprol) 1.5 1.8 9.6 0.7 3.1 0.2 -0.8 0.3 0.5 -1.0 1.6
Pain experienced in last month 0.8 1.4 3.2 -0.6 -1.3 -1.8 1.3 -1.4 -0.1 1.2 -1.1
Supplements: Calcium 0.5 0.5 2.0 0.7 -0.2 -1.2 0.0 -1.4 0.3 0.5 -0.1
Basal cell carcinoma (self-reported) 0.5 0.6 2.3 0.7 0.6 1.0 -0.4 -0.4 -1.5 -0.2 0.5
Heart attack/myocardial infarction (self-reported) 1.4 1.8 4.7 -1.5 -0.8 -0.7 1.7 -1.3 0.1 2.2 -1.5
Deep venous thrombosis (DVT) (self-reported) 0.4 0.6 2.2 1.5 0.5 -0.6 -0.2 -0.6 -0.1 0.5 1.0
Heart disease (siblings) 1.8 2.2 7.6 -0.2 -1.6 -0.8 2.8 -0.3 1.3 1.8 -1.4
Alcohol drinker status: Previous 2.1 2.4 5.3 1.5 1.5 -2.3 2.3 -0.5 1.0 1.8 0.2
Pack years of smoking 0.3 0.4 1.1 0.0 -0.9 -1.1 0.2 -0.9 -0.1 0.7 -0.5
Impedance of whole body 0.5 2.7 7.0 -1.4 -0.6 -1.8 1.5 -2.6 1.5 0.7 -2.0
Leg fat mass (left) 4.1 15.9 30.5 5.5 3.2 1.7 -3.3 5.1 -3.4 -2.1 5.5
Arm predicted mass (left) 1.3 6.4 17.6 3.0 3.1 0.5 -1.8 4.2 -1.1 -0.0 3.2