[Hub]/) : Traits : Arm fat percentage (right) : ← →

chr11:26,818,083-29,054,545

Best TWAS P=1.74e-21 · Best GWAS P=3.68e-30 conditioned to 5.81e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 9.38 9.4 6.5e-21 0.63 0.74 0.14 FALSE
2 GTEx Brain Putamen basal ganglia BDNF-AS 0.22 0.17 lasso 4 0.13 5.5e-04 -6.45 7.7 1.8e-14 0.33 0.23 0.05 TRUE
3 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 9.38 7.7 1.4e-14 0.62 1.00 0.00 FALSE
4 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 2.85 6.6 3.2e-11 0.60 0.69 0.16 FALSE
5 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 -0.22 -7.3 3.5e-13 -0.68 0.02 0.83 FALSE
6 GTEx Nerve Tibial LIN7C 0.18 0.08 enet 27 0.12 4.2e-09 9.38 6.3 2.3e-10 0.56 0.62 0.35 FALSE
7 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 9.38 9.1 1.4e-19 0.69 0.52 0.36 FALSE
8 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 9.69 -9.5 1.7e-21 -0.72 0.10 0.80 TRUE
9 ROSMAP Brain Pre-frontal Cortex METTL15 0.04 0.03 blup 364 0.03 4.6e-05 -3.55 -5.7 1.5e-08 -0.19 0.72 0.01 TRUE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma LIN7C 0.04 0.01 lasso 3 0.02 1.0e-02 -2.11 5.9 3.3e-09 0.46 0.02 0.82 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 9.74 7.5 8.0e-14 0.57 0.01 0.95 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 9.71 8.6 6.4e-18 0.63 0.01 0.98 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma LIN7C 0.09 0.12 lasso 2 0.12 2.6e-13 2.96 5.1 2.8e-07 0.52 0.94 0.06 FALSE