Best TWAS P=2.41e-08 · Best GWAS P=9.24e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | AC090945.1 | 0.10 | 0.12 | lasso | 7 | 0.11 | 2.8e-14 | 5.3 | 5.6 | 2.4e-08 | 0.97 | 0.02 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BTD | 0.04 | 0.02 | lasso | 3 | 0.02 | 6.5e-03 | 4.9 | 5.1 | 2.9e-07 | 0.70 | 0.01 | 0.62 | FALSE |