Best TWAS P=1.7e-07 · Best GWAS P=2.23e-08 conditioned to 7.63e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ZDHHC4 | 0.29 | 0.09 | enet | 19 | 0.13 | 7.5e-08 | 3.7 | -5.2 | 2.6e-07 | -0.27 | 0.86 | 0.06 | TRUE |
| 2 | GTEx | Esophagus Mucosa | AC092171.4 | 0.14 | 0.07 | lasso | 3 | 0.05 | 3.2e-04 | 5.0 | 5.2 | 1.7e-07 | -0.10 | 0.00 | 0.99 | TRUE |
| 3 | METSIM | Adipose | FBXL18 | 0.08 | 0.06 | lasso | 3 | 0.05 | 1.6e-07 | 5.0 | 5.2 | 2.1e-07 | -0.10 | 0.00 | 1.00 | FALSE |