Best TWAS P=2.08e-10 · Best GWAS P=2.74e-10 conditioned to 0.0094
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RP11-179B2.2 | 0.13 | 0.02 | lasso | 3 | 0.03 | 6.5e-03 | 5.5 | 5.2 | 2.4e-07 | 0.71 | 0.12 | 0.76 | FALSE |
2 | GTEx | Artery Aorta | RP11-179B2.2 | 0.16 | 0.11 | lasso | 2 | 0.09 | 7.6e-06 | 5.5 | 5.5 | 4.5e-08 | 0.73 | 0.11 | 0.85 | FALSE |
3 | GTEx | Brain Cerebellum | RP11-179B2.2 | 0.37 | 0.21 | lasso | 4 | 0.20 | 1.4e-06 | 5.5 | 6.4 | 2.1e-10 | 0.70 | 0.12 | 0.73 | TRUE |
4 | GTEx | Esophagus Muscularis | RP11-179B2.2 | 0.15 | 0.16 | lasso | 3 | 0.16 | 8.1e-10 | 5.3 | 5.3 | 1.4e-07 | 0.71 | 0.23 | 0.77 | FALSE |
5 | GTEx | Heart Left Ventricle | RP11-179B2.2 | 0.15 | 0.18 | enet | 2 | 0.14 | 4.8e-08 | 5.5 | 5.5 | 3.2e-08 | 0.74 | 0.10 | 0.90 | FALSE |
6 | GTEx | Lung | RP11-179B2.2 | 0.18 | 0.12 | lasso | 3 | 0.12 | 1.7e-09 | 5.5 | 5.1 | 2.6e-07 | 0.71 | 0.14 | 0.86 | FALSE |