[Hub]/) : Traits : Arm fat-free mass (right) :

chr6:129,638,583-131,163,098

Best TWAS P=6.08e-60 · Best GWAS P=8.51e-55 conditioned to 0.583

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous L3MBTL3 0.20 0.08 lasso 4 0.09 1.1e-07 15.6 16.0 1.8e-57 0.94 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum L3MBTL3 0.14 0.12 lasso 2 0.15 2.8e-08 15.6 16.1 1.9e-58 0.94 0.00 1.00 FALSE
3 GTEx Breast Mammary Tissue L3MBTL3 0.31 0.25 lasso 7 0.23 2.8e-12 15.6 16.0 1.2e-57 0.97 0.00 1.00 FALSE
4 GTEx Breast Mammary Tissue RP11-73O6.3 0.27 0.22 lasso 9 0.22 1.5e-11 15.6 15.9 1.3e-56 0.97 0.00 1.00 FALSE
5 GTEx Breast Mammary Tissue (Male) L3MBTL3 0.31 0.24 lasso 6 0.23 5.5e-06 15.6 16.1 1.2e-58 0.94 0.00 0.98 FALSE
6 GTEx Breast Mammary Tissue (Male) RP11-73O6.3 0.33 0.17 lasso 4 0.12 1.3e-03 15.6 15.1 1.7e-51 0.94 0.01 0.96 FALSE
7 GTEx Breast Mammary Tissue (Female) L3MBTL3 0.30 0.13 lasso 5 0.14 4.5e-05 11.6 15.6 9.4e-55 0.93 0.01 0.98 FALSE
8 GTEx Breast Mammary Tissue (Female) RP11-73O6.3 0.29 0.08 lasso 5 0.10 5.7e-04 13.3 15.6 9.2e-55 0.90 0.01 0.97 FALSE
9 GTEx Cells EBV-transformed lymphocytes L3MBTL3 0.28 0.08 lasso 10 0.03 4.4e-02 15.6 14.7 1.2e-48 0.85 0.01 0.97 FALSE
10 GTEx Colon Transverse L3MBTL3 0.27 0.13 lasso 8 0.20 8.0e-10 15.6 15.6 4.9e-55 0.88 0.00 1.00 FALSE
11 GTEx Colon Transverse RP11-73O6.3 0.19 0.09 lasso 2 0.06 1.2e-03 15.6 16.0 2.7e-57 0.99 0.00 1.00 FALSE
12 GTEx Esophagus Mucosa L3MBTL3 0.26 0.18 lasso 2 0.23 2.7e-15 13.3 15.5 1.8e-54 0.93 0.00 1.00 FALSE
13 GTEx Lung L3MBTL3 0.37 0.34 lasso 4 0.38 4.1e-30 15.6 16.2 4.9e-59 0.96 0.00 1.00 FALSE
14 GTEx Lung RP11-73O6.3 0.15 0.08 lasso 5 0.12 2.2e-09 15.6 16.0 7.6e-58 0.93 0.00 1.00 FALSE
15 GTEx Nerve Tibial L3MBTL3 0.30 0.23 lasso 4 0.22 2.3e-15 15.6 16.1 3.2e-58 0.99 0.00 1.00 FALSE
16 GTEx Pancreas L3MBTL3 0.32 0.17 lasso 4 0.23 4.4e-10 15.6 16.1 1.3e-58 0.98 0.00 1.00 FALSE
17 GTEx Pituitary L3MBTL3 0.45 0.31 lasso 8 0.29 5.1e-08 11.6 13.8 4.1e-43 0.85 0.00 0.99 FALSE
18 GTEx Pituitary RP11-73O6.3 0.48 0.07 lasso 7 0.16 8.2e-05 11.6 11.7 1.0e-31 0.78 0.01 0.98 FALSE
19 GTEx Prostate L3MBTL3 0.35 0.27 lasso 5 0.17 5.9e-05 15.6 15.8 3.2e-56 0.97 0.00 0.99 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic L3MBTL3 0.26 0.12 lasso 4 0.12 4.0e-07 12.3 15.3 5.5e-53 0.92 0.00 1.00 FALSE
21 GTEx Skin Sun Exposed Lower leg L3MBTL3 0.25 0.25 lasso 9 0.24 1.4e-19 15.6 15.8 3.1e-56 0.97 0.00 1.00 FALSE
22 GTEx Small Intestine Terminal Ileum L3MBTL3 0.37 0.20 lasso 4 0.17 1.3e-04 15.6 16.0 2.0e-57 0.98 0.00 0.98 FALSE
23 GTEx Spleen L3MBTL3 0.64 0.34 enet 14 0.48 6.4e-14 13.3 15.8 3.8e-56 0.87 0.02 0.98 FALSE
24 GTEx Spleen RP11-73O6.3 0.45 0.43 enet 21 0.42 7.7e-12 13.3 14.7 1.1e-48 0.82 0.05 0.95 FALSE
25 GTEx Stomach L3MBTL3 0.36 0.18 enet 27 0.20 1.1e-09 14.9 14.6 1.6e-48 0.77 0.02 0.98 FALSE
26 GTEx Stomach RP11-73O6.3 0.21 0.12 lasso 6 0.06 5.9e-04 14.9 14.9 2.8e-50 0.73 0.13 0.53 FALSE
27 GTEx Testis L3MBTL3 0.41 0.22 lasso 8 0.30 9.2e-14 15.6 14.9 3.6e-50 0.90 0.00 1.00 FALSE
28 GTEx Thyroid L3MBTL3 0.40 0.39 enet 9 0.43 2.8e-35 15.6 16.3 6.1e-60 0.95 0.00 1.00 TRUE
29 GTEx Thyroid RP11-73O6.3 0.18 0.15 lasso 3 0.20 2.3e-15 13.8 16.0 1.5e-57 0.91 0.00 1.00 FALSE
30 GTEx Whole Blood L3MBTL3 0.22 0.20 lasso 9 0.20 5.1e-18 15.6 16.1 5.5e-58 0.98 0.00 1.00 FALSE
31 GTEx Whole Blood RP11-73O6.3 0.15 0.06 lasso 8 0.04 1.1e-04 15.6 15.9 3.4e-57 0.97 0.00 1.00 FALSE
32 METSIM Adipose L3MBTL3 0.13 0.12 enet 22 0.12 4.8e-18 13.3 11.9 7.9e-33 0.72 0.99 0.01 FALSE
33 ROSMAP Brain Pre-frontal Cortex L3MBTL3 0.14 0.07 blup 609 0.08 3.8e-10 15.6 12.2 5.1e-34 0.72 0.00 1.00 FALSE
34 YFS Blood L3MBTL3 0.28 0.22 blup 614 0.27 1.2e-88 13.3 12.7 7.8e-37 0.74 1.00 0.00 FALSE
35 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma L3MBTL3 0.05 0.00 blup 114 0.01 1.0e-02 9.7 6.3 2.6e-10 0.33 0.03 0.22 FALSE
36 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma L3MBTL3 0.06 0.01 blup 114 0.04 4.0e-03 13.3 12.5 1.0e-35 0.77 0.02 0.87 FALSE