Best TWAS P=1.27e-08 · Best GWAS P=1.73e-08 conditioned to 1.63e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | LINC00094 | 0.14 | 0.01 | enet | 40 | 0.03 | 1.7e-03 | -3.8 | -5.1 | 2.9e-07 | -0.01 | 0.53 | 0.08 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ABO | 0.27 | 0.31 | blup | 43 | 0.33 | 2.1e-19 | -4.9 | -5.1 | 2.6e-07 | 0.08 | 0.00 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ABO | 0.23 | 0.21 | lasso | 5 | 0.20 | 6.7e-09 | -5.1 | -5.2 | 2.4e-07 | 0.07 | 0.00 | 0.99 | FALSE |
4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | ABO | 0.48 | 0.23 | enet | 10 | 0.27 | 4.7e-07 | -5.0 | -5.7 | 1.3e-08 | 0.08 | 0.00 | 0.96 | TRUE |