Best TWAS P=6.73e-10 · Best GWAS P=5.79e-07 conditioned to 0.0873
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | SNHG7 | 0.37 | 0.10 | lasso | 6 | 0.27 | 2.5e-08 | -3.4 | 6.2 | 6.7e-10 | 0.39 | 0.06 | 0.57 | TRUE |
| 2 | GTEx | Ovary | INPP5E | 0.24 | 0.13 | enet | 11 | 0.15 | 1.9e-04 | 4.5 | -5.8 | 5.8e-09 | -0.59 | 0.05 | 0.62 | FALSE |
| 3 | GTEx | Ovary | SEC16A | 0.33 | 0.06 | enet | 10 | 0.14 | 3.4e-04 | 4.3 | -5.5 | 3.9e-08 | -0.45 | 0.04 | 0.27 | TRUE |
| 4 | GTEx | Uterus | INPP5E | 0.60 | 0.04 | enet | 10 | 0.22 | 3.4e-05 | 4.8 | -5.3 | 1.3e-07 | -0.53 | 0.04 | 0.46 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | INPP5E | 0.07 | 0.04 | blup | 54 | 0.07 | 6.0e-05 | 5.0 | -5.3 | 1.3e-07 | -0.84 | 0.01 | 0.94 | FALSE |