Best TWAS P=5.34e-09 · Best GWAS P=2.04e-07 conditioned to 0.319
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CACUL1 | 0.12 | 0.08 | lasso | 4 | 0.06 | 1.2e-08 | -5.2 | 5.2 | 1.6e-07 | -1.00 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C10orf46 | 0.23 | 0.04 | lasso | 4 | 0.04 | 8.6e-03 | -5.2 | 5.8 | 5.3e-09 | -0.95 | 0.01 | 0.66 | TRUE |