[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr12:101,392,911-103,148,974

Best TWAS P=8.77e-09 · Best GWAS P=9.33e-13 conditioned to 2.92e-13

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC53 0.21 0.15 blup 448 0.19 2.4e-22 3.9 -5.5 4.5e-08 -0.06 0.99 0.01 FALSE
2 GTEx Cells Transformed fibroblasts CCDC53 0.10 0.18 lasso 1 0.17 1.5e-12 5.6 -5.6 1.8e-08 0.08 0.93 0.07 FALSE
3 GTEx Colon Transverse CHPT1 0.25 0.04 enet 36 0.18 5.1e-09 4.0 -5.4 8.3e-08 -0.10 0.81 0.02 FALSE
4 GTEx Esophagus Mucosa CCDC53 0.31 0.41 enet 17 0.43 1.0e-30 3.9 -5.1 3.0e-07 0.04 0.96 0.04 FALSE
5 GTEx Heart Left Ventricle CCDC53 0.14 0.20 lasso 4 0.18 9.6e-10 5.7 -5.3 1.3e-07 0.08 0.94 0.05 FALSE
6 GTEx Spleen CCDC53 0.25 0.19 lasso 11 0.16 5.8e-05 5.7 -5.7 1.0e-08 0.09 0.48 0.11 TRUE
7 METSIM Adipose DRAM1 0.12 0.03 enet 24 0.08 1.1e-12 4.0 5.8 8.8e-09 0.07 0.95 0.04 TRUE
8 YFS Blood DRAM1 0.33 0.13 enet 101 0.19 1.6e-58 5.6 5.5 4.0e-08 0.03 0.89 0.11 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma CCDC53 0.07 0.07 blup 55 0.06 1.3e-04 5.0 -5.2 2.0e-07 0.14 0.90 0.03 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma CCDC53 0.14 0.08 blup 50 0.08 1.8e-03 5.7 -5.5 3.1e-08 0.13 0.14 0.06 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC53 0.06 0.10 lasso 3 0.10 7.3e-11 5.7 -5.1 2.7e-07 0.09 0.91 0.09 FALSE
12 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C12orf48 0.09 0.08 lasso 4 0.07 3.5e-04 4.9 5.1 3.1e-07 -0.15 0.04 0.84 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC53 0.04 0.07 lasso 4 0.06 2.1e-05 5.7 -5.7 1.5e-08 0.09 0.76 0.08 FALSE