TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat-free mass (right)
:
←
→
chr12:93,165,619-94,675,142
Best TWAS P=3.65e-19 · Best GWAS P=1.2e-40 conditioned to 8.33e-21
93.2M
93.4M
93.6M
93.8M
94M
94.2M
94.4M
94.6M
0
10
20
30
40
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Breast Mammary Tissue (Male)
MRPL42
0.21
-0.01
lasso
2
-0.01
6.0e-01
9.1
-8.9
3.6e-19
-0.48
0.05
0.06
TRUE
3
YFS
Blood
SOCS2
0.06
0.04
bslmm
444
0.04
1.7e-12
6.2
7.5
5.5e-14
0.01
1.00
0.00
TRUE
2
GTEx
Muscle Skeletal
MRPL42
0.07
0.02
lasso
3
0.04
1.5e-04
-5.2
-5.5
4.4e-08
-0.17
0.69
0.01
TRUE