[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr14:24,098,631-25,546,115

Best TWAS P=5.03e-12 · Best GWAS P=2.79e-11 conditioned to 0.394

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	6.4	6.9	5.0e-12	0.71	0.02	0.98	TRUE
2	GTEx	Spleen	NFATC4	0.45	0.00	enet	24	0.00	2.5e-01	4.4	-6.0	2.1e-09	-0.22	0.07	0.06	TRUE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	4.5	5.2	1.6e-07	0.70	0.03	0.77	TRUE
1	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	6.1	5.1	3.0e-07	0.48	0.06	0.87	TRUE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	5.9	6.7	2.2e-11	0.75	0.03	0.97	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	4.4	5.6	1.8e-08	0.73	0.84	0.16	FALSE
8	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	5.5	-5.5	3.4e-08	-0.70	0.04	0.56	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	3.9	5.1	3.1e-07	0.71	0.04	0.75	FALSE