TWAS
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Traits
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Traits
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Arm fat-free mass (right)
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chr15:41,221,067-42,749,023
Best TWAS P=7.31e-09 · Best GWAS P=3e-10 conditioned to 4.35e-08
41.2M
41.4M
41.6M
41.8M
42M
42.2M
42.4M
42.6M
42.8M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
CHP
0.06
0.01
blup
54
0.03
4.7e-04
-3.3
5.8
7.3e-09
0.03
0.03
0.14
TRUE
1
YFS
Blood
MGA
0.01
0.00
blup
454
0.00
7.1e-02
-3.3
-5.3
1.1e-07
-0.27
0.12
0.10
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
CHP
0.21
0.11
lasso
4
0.12
5.1e-13
-5.0
5.4
7.2e-08
0.08
0.00
1.00
FALSE