Best TWAS P=2.62e-08 · Best GWAS P=5.36e-08 conditioned to 0.0252
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | APOBEC3G | 0.40 | 0.40 | lasso | 3 | 0.39 | 6.3e-23 | 4.9 | 5.3 | 1.1e-07 | 0.58 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Pituitary | APOBEC3G | 0.34 | 0.04 | enet | 11 | 0.11 | 1.2e-03 | 4.6 | 5.6 | 2.6e-08 | 0.68 | 0.03 | 0.77 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | APOBEC3G | 0.10 | 0.09 | lasso | 3 | 0.06 | 7.5e-06 | 4.9 | 5.2 | 1.9e-07 | 0.54 | 0.04 | 0.95 | FALSE |
| 4 | GTEx | Vagina | APOBEC3G | 0.23 | 0.07 | lasso | 5 | 0.06 | 1.8e-02 | 4.6 | 5.2 | 2.4e-07 | 0.57 | 0.07 | 0.38 | FALSE |