[Hub]/) : Traits : Arm fat-free mass (right) : ←

chr22:40,195,017-43,232,818

Best TWAS P=7.6e-11 · Best GWAS P=3.14e-16 conditioned to 0.000366

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CYP2D6	0.26	0.10	enet	34	0.20	1.2e-16	-4.3	-6.2	5.6e-10	0.45	1.00	0.00	TRUE
2	GTEx	Adrenal Gland	CYP2D6	0.37	0.14	lasso	12	0.16	2.3e-06	-4.4	-5.2	1.8e-07	0.41	0.97	0.00	FALSE
3	GTEx	Brain Cerebellar Hemisphere	CYP2D7P1	0.39	0.09	enet	12	0.20	7.2e-06	-3.1	-5.3	9.3e-08	0.50	0.28	0.50	FALSE
4	GTEx	Brain Frontal Cortex BA9	SLC25A17	0.11	-0.01	lasso	5	0.00	3.5e-01	-4.1	-5.2	1.9e-07	0.22	0.08	0.18	TRUE
5	GTEx	Breast Mammary Tissue (Male)	CYP2D6	0.34	-0.01	lasso	6	0.00	3.2e-01	4.5	-5.4	5.6e-08	0.36	0.11	0.10	FALSE
6	GTEx	Breast Mammary Tissue (Female)	POLR3H	0.09	-0.01	lasso	6	-0.01	6.4e-01	-5.6	5.6	1.7e-08	-0.46	0.04	0.06	FALSE
7	GTEx	Breast Mammary Tissue (Female)	DESI1	0.14	0.07	lasso	4	0.11	4.2e-04	-5.6	5.3	8.9e-08	-0.45	0.08	0.12	FALSE
8	GTEx	Colon Sigmoid	DESI1	0.21	0.08	enet	6	0.11	1.2e-04	-5.6	5.4	6.3e-08	-0.47	0.40	0.05	FALSE
9	GTEx	Heart Left Ventricle	RP4-669P10.16	0.11	0.06	lasso	2	0.06	3.4e-04	-4.0	-5.2	2.4e-07	0.62	0.10	0.72	FALSE
10	GTEx	Lung	RP5-821D11.7	0.08	0.02	enet	21	0.04	6.6e-04	3.6	6.1	1.2e-09	-0.40	0.53	0.04	FALSE
11	GTEx	Nerve Tibial	CYP2D6	0.32	0.21	lasso	6	0.24	2.8e-17	4.1	-5.2	1.8e-07	0.39	1.00	0.00	FALSE
12	GTEx	Skin Sun Exposed Lower leg	CENPM	0.05	0.00	enet	8	0.02	1.5e-02	-5.0	5.4	5.8e-08	-0.53	0.07	0.43	TRUE
13	GTEx	Spleen	CCDC134	0.23	0.00	enet	14	0.09	2.7e-03	-5.6	5.8	5.2e-09	-0.40	0.07	0.07	FALSE
14	GTEx	Testis	SREBF2	0.25	0.03	lasso	12	0.04	4.6e-03	4.1	5.3	1.2e-07	-0.41	0.62	0.04	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	TNRC6B	0.02	0.01	blup	92	0.01	2.7e-03	-5.2	-5.8	8.2e-09	0.12	0.02	0.78	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	WBP2NL	0.06	0.04	blup	140	0.03	9.6e-05	-5.6	6.1	8.4e-10	-0.53	0.58	0.24	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADSL	0.04	0.03	enet	6	0.03	1.6e-04	-6.7	-5.6	2.5e-08	0.02	0.00	0.94	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WBP2NL	0.10	0.04	blup	140	0.05	1.8e-06	-3.8	5.9	2.9e-09	-0.40	0.98	0.00	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	ADSL	0.03	0.00	blup	33	0.01	8.9e-03	-6.4	-5.7	1.2e-08	0.06	0.01	0.60	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADSL	0.06	0.02	lasso	2	0.03	6.6e-03	-6.5	-6.5	7.6e-11	0.05	0.00	0.81	TRUE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADSL	0.09	0.03	lasso	3	0.01	7.7e-02	-6.7	-6.5	8.3e-11	0.11	0.00	0.76	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CSDC2	0.25	0.01	enet	11	0.06	2.3e-03	-3.2	-5.4	7.2e-08	0.21	0.00	0.00	TRUE