[Hub]/) : Traits : Arm fat-free mass (right) :

chr3:52,242,902-53,860,103

Best TWAS P=1.04e-09 · Best GWAS P=2.52e-08 conditioned to 0.149

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Prostate RFT1 0.39 0.18 enet 17 0.24 1.1e-06 3.3 5.3 9.8e-08 0.63 0.10 0.83 TRUE
2 GTEx Stomach RFT1 0.23 0.03 enet 19 0.06 6.3e-04 3.3 5.2 1.6e-07 0.60 0.09 0.80 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma RFT1 0.18 0.10 lasso 7 0.10 1.8e-08 5.0 5.2 1.9e-07 0.75 0.00 0.99 FALSE
4 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM110 0.19 0.13 blup 59 0.13 4.2e-11 4.4 5.2 1.7e-07 0.76 0.11 0.88 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma RFT1 0.10 0.08 enet 11 0.15 2.3e-29 4.8 5.2 2.7e-07 0.61 0.03 0.96 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma RFT1 0.10 0.05 enet 12 0.05 1.0e-03 5.1 5.2 1.8e-07 0.67 0.01 0.91 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma NISCH 0.06 0.05 lasso 4 0.04 7.5e-06 5.3 5.2 2.5e-07 0.84 0.00 1.00 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma SPCS1 0.15 0.03 lasso 3 0.04 4.3e-05 4.9 5.5 4.8e-08 0.86 0.00 0.84 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM110 0.13 0.06 blup 59 0.08 3.3e-09 3.4 5.2 1.7e-07 0.62 0.75 0.16 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RFT1 0.31 0.07 blup 45 0.19 1.8e-09 2.9 5.8 8.4e-09 0.65 0.02 0.97 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma RFT1 0.14 0.11 blup 45 0.11 1.9e-12 4.8 5.2 2.0e-07 0.71 0.01 0.99 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma SPCS1 0.11 0.00 blup 41 0.01 9.9e-03 -3.5 6.1 1.0e-09 0.50 0.00 0.12 TRUE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RFT1 0.07 0.03 enet 7 0.06 1.2e-07 4.6 5.3 1.3e-07 0.56 0.01 0.98 FALSE
14 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMEM110 0.20 0.13 blup 59 0.15 3.0e-10 5.3 5.4 5.8e-08 0.75 0.01 0.99 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM110 0.20 0.06 blup 59 0.10 1.2e-10 5.3 5.3 8.7e-08 0.79 0.01 0.99 FALSE
16 The Cancer Genome Atlas Soft Tissue Sarcoma RFT1 0.16 0.12 enet 16 0.14 1.7e-08 5.0 5.2 2.1e-07 0.69 0.01 0.99 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma TMEM110 0.12 0.07 blup 59 0.12 7.5e-08 5.2 5.2 2.0e-07 0.65 0.03 0.96 FALSE
18 The Cancer Genome Atlas Skin Cutaneous Melanoma RFT1 0.29 0.04 blup 45 0.11 8.2e-04 4.8 5.5 4.8e-08 0.59 0.01 0.80 FALSE
19 The Cancer Genome Atlas Stomach Adenocarcinoma RFT1 0.13 0.05 blup 45 0.10 6.9e-08 5.1 5.7 1.1e-08 0.63 0.01 0.98 FALSE
20 The Cancer Genome Atlas Testicular Germ Cell Tumors RFT1 0.39 0.22 lasso 4 0.25 3.1e-09 4.9 5.1 3.0e-07 0.73 0.01 0.99 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors TMEM110 0.20 0.01 lasso 2 0.09 3.2e-04 5.3 5.3 9.3e-08 0.75 0.01 0.83 FALSE
22 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RFT1 0.29 0.15 blup 45 0.15 6.5e-05 4.6 5.9 4.7e-09 0.62 0.01 0.84 FALSE