Best TWAS P=7.91e-09 · Best GWAS P=3.29e-07 conditioned to 0.0113
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | WDR19 | 0.28 | 0.29 | lasso | 5 | 0.27 | 1.6e-12 | -4.8 | 5.2 | 2.4e-07 | 0.87 | 0.04 | 0.95 | FALSE |
| 2 | METSIM | Adipose | WDR19 | 0.04 | 0.01 | enet | 20 | 0.02 | 7.7e-04 | -5.0 | 5.8 | 7.9e-09 | 0.51 | 0.04 | 0.94 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | WDR19 | 0.02 | 0.02 | enet | 9 | 0.02 | 2.8e-03 | 5.1 | 5.2 | 1.6e-07 | 0.99 | 0.03 | 0.90 | FALSE |