[Hub]/) : Traits : Arm fat-free mass (right) :

chr4:16,922,182-18,507,692

Best TWAS P=6.63e-49 · Best GWAS P=1.16e-44 conditioned to 0.000264

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 8.4 8.4 3.4e-17 -0.24 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 8.4 9.8 7.3e-23 -0.35 0.29 0.46 FALSE
3 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -13.2 14.7 6.6e-49 -0.81 0.05 0.78 TRUE
4 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 9.5 10.7 9.6e-27 -0.36 1.00 0.00 FALSE
5 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 8.4 11.2 5.3e-29 -0.52 0.14 0.67 FALSE
6 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -12.3 12.1 1.5e-33 -0.76 0.04 0.58 FALSE
7 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 8.4 8.5 1.7e-17 -0.27 0.06 0.08 FALSE
8 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 8.4 8.9 4.0e-19 -0.37 0.13 0.40 FALSE
9 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 8.4 8.2 2.9e-16 -0.27 0.99 0.00 FALSE
10 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 8.4 9.6 7.3e-22 -0.37 0.99 0.01 FALSE
11 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 8.4 8.7 5.1e-18 -0.38 0.07 0.33 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 9.2 10.3 1.1e-24 -0.35 0.64 0.04 FALSE
13 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 8.4 9.5 3.2e-21 -0.28 1.00 0.00 FALSE
14 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 8.4 13.0 6.5e-39 -0.66 0.05 0.56 FALSE
15 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 9.3 10.3 8.8e-25 -0.26 0.19 0.05 FALSE
16 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 8.4 12.2 2.4e-34 -0.54 0.17 0.70 FALSE
17 ROSMAP Brain Pre-frontal Cortex FAM184B 0.17 0.14 enet 31 0.18 5.1e-23 -4.9 -6.7 2.8e-11 0.26 1.00 0.00 FALSE
18 ROSMAP Brain Pre-frontal Cortex MED28 0.02 0.01 bslmm 411 0.00 1.9e-01 -4.6 6.2 5.9e-10 -0.30 0.22 0.03 FALSE
19 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -12.4 11.8 2.6e-32 -0.83 0.03 0.89 FALSE
20 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 9.5 9.5 1.9e-21 -0.25 0.84 0.04 FALSE
21 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -12.7 -11.1 1.0e-28 0.84 0.01 0.99 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -12.4 -12.1 1.9e-33 0.84 0.60 0.39 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 9.5 13.5 1.4e-41 -0.64 0.15 0.63 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -12.7 -12.7 8.7e-37 0.88 0.02 0.59 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -12.7 -8.3 1.1e-16 0.68 0.02 0.83 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 8.4 12.1 1.3e-33 -0.58 0.28 0.20 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -11.4 -10.4 2.2e-25 0.76 0.03 0.43 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 9.3 13.0 9.7e-39 -0.65 0.14 0.79 FALSE