[Hub]/) : Traits : Arm fat-free mass (right) :

chr1:36,079,508-37,494,602

Best TWAS P=5.87e-10 · Best GWAS P=1.86e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-268J15.5 0.17 0.14 lasso 2 0.11 2.8e-06 -6.0 -5.7 9.8e-09 0.99 0 1 FALSE
2 GTEx Artery Aorta RP11-268J15.5 0.20 0.14 lasso 4 0.13 1.2e-07 -6.0 -6.2 5.9e-10 1.00 0 1 TRUE
3 GTEx Artery Tibial RP11-268J15.5 0.11 0.10 lasso 3 0.08 4.1e-07 -6.0 -5.7 1.2e-08 0.99 0 1 FALSE
4 GTEx Lung RP11-268J15.5 0.27 0.16 lasso 4 0.15 1.6e-11 -6.0 -5.8 5.1e-09 0.98 0 1 FALSE
5 GTEx Lung SH3D21 0.12 0.02 lasso 1 0.03 2.1e-03 -6.0 6.0 1.9e-09 -1.00 0 1 FALSE
6 GTEx Nerve Tibial RP11-268J15.5 0.18 0.09 lasso 5 0.08 1.5e-06 -6.0 -5.4 7.2e-08 0.96 0 1 FALSE
7 GTEx Skin Sun Exposed Lower leg SH3D21 0.15 0.07 lasso 5 0.08 4.7e-07 5.8 6.0 2.7e-09 -0.88 0 1 FALSE
8 GTEx Thyroid RP11-268J15.5 0.13 0.12 lasso 4 0.10 2.7e-08 -6.0 -5.9 3.2e-09 1.00 0 1 FALSE
9 METSIM Adipose RP11-268J15.5 0.05 0.06 lasso 3 0.05 4.0e-08 -6.0 -5.7 1.6e-08 0.99 0 1 FALSE
10 METSIM Adipose SH3D21 0.05 0.05 lasso 3 0.04 5.1e-07 -6.0 5.9 2.9e-09 -0.99 0 1 FALSE
11 ROSMAP Brain Pre-frontal Cortex RP11-268J15.5 0.21 0.16 lasso 5 0.17 4.3e-21 -6.0 -5.5 4.8e-08 0.96 0 1 FALSE
12 ROSMAP Brain Pre-frontal Cortex SH3D21 0.28 0.18 lasso 5 0.19 4.1e-24 -6.0 5.9 3.8e-09 -0.99 0 1 FALSE