Best TWAS P=2.89e-09 · Best GWAS P=9.61e-08 conditioned to 0.226
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | FHL3 | 0.24 | 0.15 | enet | 17 | 0.34 | 7.4e-13 | 4.5 | 5.7 | 9.8e-09 | -0.79 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Artery Aorta | FHL3 | 0.35 | 0.22 | lasso | 4 | 0.27 | 3.9e-15 | 4.5 | 5.3 | 1.3e-07 | -0.91 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Pancreas | FHL3 | 0.17 | 0.05 | lasso | 3 | 0.10 | 6.6e-05 | -5.3 | 5.5 | 4.6e-08 | -0.91 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | FHL3 | 0.10 | 0.05 | lasso | 2 | 0.06 | 2.9e-04 | 4.8 | 5.4 | 7.6e-08 | -0.92 | 0.00 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FHL3 | 0.08 | 0.08 | lasso | 2 | 0.08 | 1.4e-09 | -5.3 | 5.3 | 1.4e-07 | -0.99 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | FHL3 | 0.13 | 0.03 | enet | 6 | 0.05 | 4.9e-04 | -5.3 | 5.9 | 2.9e-09 | -0.77 | 0.00 | 0.92 | TRUE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FHL3 | 0.10 | 0.05 | lasso | 2 | 0.03 | 2.2e-03 | -5.3 | 5.2 | 2.1e-07 | -0.99 | 0.00 | 0.94 | FALSE |