[Hub]/) : Traits : Arm predicted mass (right) : →

chr1:752,566-3,191,909

Best TWAS P=1.65e-11 · Best GWAS P=2.8e-09 conditioned to 9.29e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 -4.3 -5.8 7.0e-09 0.37 0.37 0.16 FALSE
2 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -3.1 -5.2 2.2e-07 0.21 0.15 0.09 TRUE
3 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 -5.3 -5.5 4.1e-08 0.85 0.03 0.68 FALSE
4 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -5.9 6.5 8.2e-11 -0.91 0.01 0.72 TRUE
5 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 -5.3 5.3 1.3e-07 -0.83 0.22 0.78 FALSE
6 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 5.1 -5.6 2.4e-08 0.94 0.03 0.92 FALSE
7 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 -5.3 -5.7 1.4e-08 0.79 0.04 0.86 FALSE
8 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -5.7 5.8 7.2e-09 -0.84 0.04 0.96 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 5.1 5.4 6.1e-08 -0.92 0.03 0.97 FALSE
10 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 5.5 5.6 1.8e-08 -0.92 0.03 0.97 FALSE
11 GTEx Spleen TMEM52 0.47 0.21 lasso 5 0.22 2.3e-06 -3.7 -5.2 1.6e-07 0.58 0.25 0.36 FALSE
12 METSIM Adipose TNFRSF14 0.07 0.05 blup 373 0.05 1.9e-07 4.4 6.7 1.7e-11 -0.08 0.29 0.65 TRUE
13 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 -4.3 5.6 2.2e-08 -0.70 0.92 0.08 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 -5.3 5.6 2.0e-08 -0.91 0.01 0.77 FALSE