TWAS hub - NADK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0640	0.0270	4.6e-03	0.041	NA	0.021	NA	0.041	2.7e-04	NA	7.0e-03	NA	2.7e-04
2	GTEx	Brain Cerebellar Hemisphere	0.1790	0.0740	7.2e-03	0.107	NA	0.035	NA	0.087	1.1e-03	NA	4.4e-02	NA	3.1e-03
3	GTEx	Heart Atrial Appendage	0.1950	0.0800	1.9e-03	-0.005	NA	-0.002	NA	0.000	6.0e-01	NA	3.9e-01	NA	3.1e-01
4	GTEx	Lung	0.0673	0.0329	6.8e-03	0.027	NA	0.006	NA	0.021	3.4e-03	NA	9.7e-02	NA	8.5e-03
5	GTEx	Muscle Skeletal	0.0627	0.0261	9.3e-04	-0.002	NA	0.003	NA	-0.001	6.9e-01	NA	1.3e-01	NA	5.0e-01
6	GTEx	Ovary	0.2730	0.0920	1.7e-03	0.173	NA	0.149	NA	0.160	4.9e-05	NA	1.7e-04	NA	9.6e-05
7	GTEx	Pituitary	0.2090	0.0950	9.0e-03	0.087	NA	0.066	NA	0.052	3.5e-03	NA	9.5e-03	NA	2.0e-02
8	METSIM	Adipose	0.0699	0.0257	4.7e-05	0.024	0.038	0.042	0.043	0.039	1.5e-04	2.0e-06	6.3e-07	4.6e-07	1.3e-06
9	YFS	Blood	0.0331	0.0191	3.2e-03	0.001	0.002	0.006	0.004	0.003	1.9e-01	4.2e-02	3.6e-03	1.4e-02	2.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Systolic Blood Pressure	11.9	59.8	104.0	6.4	9.8	6.7	10.2	9.3	6.5	9.4	5.7	-0.3
Breastfed as a baby	7.4	9.2	19.8	-3.5	-4.5	-1.5	-3.6	-3.4	-2.7	-3.5	-1.8	-1.1
Impedance of whole body	6.4	32.8	58.2	4.1	7.6	5.1	7.4	7.5	4.4	6.2	4.9	0.0
Systolic blood pressure, automated reading	6.0	17.4	33.1	3.2	5.1	3.6	5.5	4.7	3.0	5.8	3.4	-1.1
Impedance of arm (left)	5.7	26.4	44.2	3.6	6.5	4.8	6.7	6.6	4.0	5.5	4.9	0.7
Comparative body size at age 10	5.3	14.6	30.1	-2.3	-4.8	-4.2	-4.9	-5.5	-2.8	-3.5	-2.0	2.6
BMI	4.8	27.9	56.0	-3.3	-6.9	-6.1	-7.0	-7.5	-3.3	-5.8	-2.1	-0.8
Impedance of arm (right)	4.8	22.2	39.1	3.1	6.2	4.3	6.2	6.1	3.3	5.2	4.3	0.4
Vascular/heart problems diagnosed by doctor	4.5	12.2	21.8	-4.4	-4.0	-2.3	-4.0	-3.4	-4.7	-3.1	-3.1	-0.6
Cardiovascular Disease	4.3	14.1	27.9	4.8	4.5	2.7	4.3	3.8	5.3	2.3	3.0	0.9
Supplements: Glucosamine	4.2	5.5	9.8	-1.7	-2.5	-2.3	-3.1	-2.6	-1.6	-2.7	-2.0	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.2	5.0	10.1	1.1	2.9	2.2	3.2	2.8	1.1	3.1	0.8	-0.8
Irritable Bowel Disease (IBD)	4.0	9.4	22.6	2.3	4.1	3.3	4.8	4.5	2.5	1.4	0.6	-0.5
Number of full brothers	4.0	5.1	12.0	-1.1	-2.8	-1.5	-2.9	-2.6	-1.3	-3.5	-2.2	-0.3
High blood pressure	3.9	11.0	21.8	4.4	3.7	1.9	3.6	3.2	4.7	2.8	2.8	1.0
Body mass index (BMI)	3.9	16.6	34.0	-1.7	-5.8	-4.6	-5.8	-5.8	-1.8	-4.4	-1.3	0.0
Impedance of leg (right)	3.7	17.8	36.2	3.3	6.0	3.7	5.3	5.7	3.2	4.1	3.2	-0.7
Waist circumference	3.7	13.5	29.8	-1.3	-5.3	-3.9	-5.3	-5.5	-1.2	-4.0	-0.9	0.1
Hypertension (Self-reported)	3.7	10.3	22.7	4.5	3.4	2.1	3.3	3.1	4.8	2.4	2.6	0.8
Vitamin and mineral supplements	3.6	4.8	10.0	2.7	1.8	1.9	1.6	1.0	2.4	3.2	3.0	-1.2
Impedance of leg (left)	3.6	17.5	34.2	3.3	5.7	3.5	5.1	5.8	3.3	4.3	3.4	-0.6
Arm predicted mass (left)	3.6	18.3	37.3	-2.4	-5.9	-3.4	-6.0	-6.1	-2.3	-4.7	-3.4	-0.4
Breast cancer (self-reported)	3.5	4.1	10.8	1.7	2.9	1.8	2.2	3.3	1.9	1.9	-0.2	0.3
Osteoarthritis (self-reported)	3.5	4.5	9.1	-2.4	-2.0	-1.7	-2.2	-1.7	-2.4	-2.2	-3.0	0.6
Arm fat-free mass (left)	3.5	18.0	36.5	-2.5	-5.8	-3.3	-5.9	-6.0	-2.4	-4.7	-3.4	-0.1
High blood pressure (mother)	3.4	4.8	9.6	1.4	2.5	0.2	3.1	2.7	1.8	2.9	2.5	-0.2
Chronic bronchitis/emphysema (mother)	3.4	4.0	7.5	-1.4	-2.1	-2.7	-2.7	-1.7	-1.7	-2.4	-0.9	-1.5
Supplements: Vitamin C	3.4	4.0	7.9	-2.8	-1.6	-1.7	-1.3	-1.7	-2.6	-2.8	-2.0	0.0
Whole body water mass	3.4	19.2	39.3	-2.8	-6.0	-3.2	-6.0	-6.3	-2.6	-4.8	-3.7	0.0
Hayfever, allergic rhinitis or eczema	3.3	7.2	13.1	3.6	3.3	1.6	3.1	2.5	3.4	0.1	2.7	-1.8
Trunk fat-free mass	3.3	18.7	36.4	-2.8	-5.8	-3.1	-5.8	-6.0	-2.7	-4.9	-4.0	-0.5
Trunk predicted mass	3.3	18.8	36.2	-2.9	-5.8	-3.1	-5.8	-6.0	-2.8	-4.9	-4.0	-0.5
Chest pain or discomfort	3.3	4.8	9.7	1.8	3.1	2.1	2.6	2.0	1.8	3.0	1.6	-0.7
Medication for cholesterol	3.3	5.0	13.8	-3.6	-1.7	-1.6	-2.2	-1.6	-3.7	-0.4	-2.3	-0.5
Medication: Blood pressure	3.3	6.2	13.2	3.2	2.2	3.0	2.6	2.3	3.6	2.1	1.5	0.4
Supplements: Fish oil (including cod liver oil)	3.3	4.3	9.8	-2.2	-1.9	-1.5	-2.2	-1.8	-2.4	-1.7	-3.1	1.4
Length of working week for main job	3.2	3.5	6.7	1.7	2.5	1.9	2.6	1.8	1.8	2.3	0.2	-0.7
Arm fat-free mass (right)	3.2	16.4	33.4	-2.1	-5.6	-2.9	-5.7	-5.8	-2.0	-4.8	-3.3	-0.5
Exposure to tobacco smoke outside home	3.2	4.3	11.6	-2.2	-2.3	-3.4	-1.9	-1.7	-2.2	-2.2	0.3	-0.1
Had major operations	3.2	3.7	8.6	-0.9	-1.8	-2.0	-2.3	-2.8	-1.1	-2.9	-1.3	-0.9
Whole body fat-free mass	3.2	18.1	36.6	-2.6	-5.8	-3.1	-5.8	-6.0	-2.5	-4.8	-3.7	-0.2
Basal metabolic rate	3.2	17.8	37.3	-2.4	-5.8	-3.3	-5.9	-6.1	-2.2	-4.8	-3.2	-0.1
Arm predicted mass (right)	3.1	15.9	32.3	-2.1	-5.5	-3.0	-5.6	-5.7	-2.0	-4.7	-3.1	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.0	3.6	5.6	2.2	2.2	2.1	2.1	2.1	2.4	1.9	0.3	0.6
Hip circumference	2.9	12.3	26.1	-2.2	-4.7	-2.6	-4.9	-5.1	-2.1	-4.1	-2.4	-0.7
Arm fat mass (right)	2.9	12.1	26.0	-1.2	-4.9	-3.8	-5.1	-5.1	-1.1	-3.9	-0.9	0.3
Ulcerative Colitis (UC)	2.8	5.3	13.4	1.1	3.0	2.6	3.7	3.6	1.6	0.5	-0.0	-1.0
Multivitamins +/- minerals	2.8	3.6	8.1	-2.0	-1.8	-1.0	-1.8	-0.9	-1.8	-2.3	-2.9	1.8
Weight	2.8	13.6	31.1	-1.5	-5.3	-3.3	-5.4	-5.6	-1.3	-4.1	-1.5	-0.2
Leg predicted mass (right)	2.7	14.3	30.4	-2.3	-5.4	-2.8	-5.2	-5.5	-1.9	-4.1	-3.0	0.4
Arm fat mass (left)	2.7	11.1	25.0	-0.9	-4.8	-3.5	-4.9	-5.0	-0.9	-3.5	-0.7	0.4
Leg fat-free mass (left)	2.6	13.6	30.6	-2.0	-5.1	-2.7	-5.1	-5.5	-1.8	-4.2	-2.8	0.2
Pulse wave reflection index	2.6	3.2	5.3	-1.9	-2.3	-2.2	-1.8	-2.1	-2.1	-1.2	-0.8	-0.8
Leg fat-free mass (right)	2.6	14.1	30.0	-2.3	-5.3	-2.8	-5.2	-5.5	-1.9	-4.1	-2.9	0.4
Leg fat mass (left)	2.6	10.0	22.0	-0.6	-4.4	-3.6	-4.7	-4.6	-0.6	-3.7	-0.6	0.0
Leg predicted mass (left)	2.5	13.2	30.0	-2.0	-5.0	-2.7	-5.0	-5.5	-1.7	-4.2	-2.7	0.2
Birth weight of first child	2.5	4.6	10.0	-1.2	-2.2	-1.9	-2.5	-1.9	-1.2	-3.2	-2.6	1.8
Leg fat mass (right)	2.5	9.5	20.5	-0.6	-4.2	-3.5	-4.5	-4.5	-0.6	-3.8	-0.4	-0.1
Medication: Ibuprofen	2.4	2.9	7.2	-1.2	-2.1	-2.1	-1.8	-1.6	-1.3	-2.7	-0.4	0.7
Allergy or Eczema	2.3	6.1	11.1	2.9	3.2	1.1	3.3	2.5	2.9	0.3	2.7	-1.6
Heart attack	2.3	2.9	4.4	1.3	1.7	1.8	2.0	1.6	1.9	2.0	2.1	0.2
Medication: Ibuprofen (e.g. Nurofen)	2.3	2.9	6.1	-1.4	-1.8	-1.8	-1.7	-1.9	-1.7	-2.5	-1.0	1.1
Heart disease (mother)	2.3	2.9	8.4	1.9	2.0	1.2	1.7	2.9	1.4	1.1	-0.5	1.3
Eye problems/disorders: Cataract	2.3	2.6	3.8	-1.7	-1.9	-0.5	-1.9	-1.5	-1.6	-1.8	-1.3	2.0
Mineral and other dietary supplements	2.3	3.1	7.1	2.6	1.1	1.2	1.3	1.0	2.7	1.6	2.4	-0.9
Average weekly spirits intake	2.2	2.8	9.7	-1.0	-1.7	-1.8	-1.6	-1.3	-0.9	-3.1	-1.8	0.0
Medication: Levothyroxine sodium	2.2	3.7	6.8	2.2	2.0	1.7	1.6	2.0	1.9	2.6	1.5	1.5
Number of operations (self-reported)	2.2	3.3	15.8	-1.6	-0.6	-0.9	-1.7	-1.0	-1.6	-4.0	-1.7	-0.8
Heart attack/myocardial infarction (self-reported)	2.2	2.8	4.7	1.5	1.6	1.6	1.9	1.4	2.1	1.8	2.2	0.1
Crohns Disease (2017)	2.1	4.6	9.6	2.2	2.7	1.9	3.1	2.9	2.1	1.3	0.7	0.9
Ever used hormone-replacement therapy (HRT)	2.1	2.7	5.9	-1.0	-1.6	-1.0	-2.0	-0.9	-1.2	-2.0	-1.7	2.4
Allergy	2.1	4.9	8.4	-2.9	-2.7	-1.6	-2.6	-2.1	-2.8	0.4	-1.4	2.1
Medication: Lansoprazole	2.1	2.4	6.2	0.4	-1.7	-2.0	-2.3	-2.5	-0.2	-1.2	-1.2	0.1
Medication: Aspirin	2.1	2.8	5.0	1.1	1.8	1.3	2.2	1.7	1.2	2.1	1.8	-1.5
Lupus	2.0	3.0	9.7	2.0	-0.7	-2.8	0.1	-0.4	1.6	-0.4	3.1	-1.4
Forced expiratory volume in 1-second (FEV1)	2.0	6.8	12.8	0.3	3.4	3.6	3.5	3.2	0.8	2.6	-0.9	2.4
Medication: Amlodipine	2.0	2.8	6.3	1.2	1.9	1.7	1.9	2.5	1.4	2.2	0.3	0.5
Qualifications: College or University degree	2.0	6.4	14.0	-3.7	-2.4	-1.6	-2.5	-1.3	-3.1	-2.6	-3.2	0.8
Knee pain experienced in last month	2.0	3.1	4.3	-1.5	-2.1	-1.6	-2.0	-2.0	-1.6	-1.8	-1.3	1.8
Osteoporosis (self-reported)	2.0	2.5	4.6	1.5	1.9	1.0	1.9	2.0	1.3	-0.1	1.2	2.1
Alcohol intake versus 10 years previously	1.9	2.8	6.4	1.2	2.0	1.7	1.6	1.9	1.3	2.5	0.8	-1.4
Ever had bowel cancer screening	1.9	2.3	5.0	-0.9	-2.0	-0.5	-2.2	-2.2	-0.7	-1.4	0.1	1.8
Medication: Atorvastatin	1.9	2.3	5.7	2.2	1.5	0.8	1.4	1.4	2.4	-0.2	1.6	-1.1
Prostate Cancer	1.8	2.5	5.9	0.2	2.4	1.8	2.3	2.2	0.3	1.5	-0.8	-0.7
Fed-up feelings	1.8	3.4	9.0	1.3	2.7	1.7	2.6	1.3	0.6	3.0	0.7	-0.1
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	4.9	-0.5	-1.8	-1.1	-2.0	-2.2	-0.4	-2.0	-0.6	1.3
Medication: Lisinopril	1.8	2.4	4.7	-1.6	-1.6	-1.7	-1.4	-1.9	-1.4	-0.8	-0.4	-2.2
Leg fat percentage (left)	1.8	6.6	15.1	0.0	-3.6	-3.3	-3.9	-3.4	-0.1	-2.9	0.4	0.2
Forced vital capacity (FVC)	1.7	6.5	13.8	-0.2	3.4	3.7	3.4	3.1	0.4	2.5	-1.3	2.2
Illnesses of mother	1.7	2.1	4.6	-2.1	-1.4	0.8	-0.9	-2.1	-1.8	-1.2	-1.3	-0.1
Blood clot in the leg (DVT)	1.7	2.2	5.6	-1.0	-1.8	-1.4	-1.8	-1.7	-1.0	-2.4	-0.9	0.1
Medication: Aspirin	1.7	2.2	4.2	1.1	1.4	1.1	2.1	1.2	1.1	1.8	1.9	-1.5
Mean Putamen Volume	1.6	1.8	3.6	1.9	1.9	1.1	1.3	0.8	1.2	1.7	0.9	0.2
Arm fat percentage (right)	1.6	6.3	13.6	-0.3	-3.5	-3.3	-3.7	-3.6	-0.3	-2.4	0.3	0.4
Leg fat percentage (right)	1.6	5.8	12.8	0.1	-3.2	-3.1	-3.6	-3.2	-0.1	-2.9	0.5	0.0
Pulse wave peak to peak time	1.6	1.8	3.9	-0.1	1.8	1.6	1.6	2.0	0.4	1.9	-0.5	-0.5
Miserableness	1.6	2.8	8.0	1.0	2.6	1.3	2.0	1.4	0.5	2.8	0.5	-1.1
Hearing aid user	1.6	1.8	4.8	1.7	0.2	1.0	0.4	0.5	1.9	0.8	2.2	1.7
Illnesses of father: High blood pressure	1.6	2.0	4.4	0.8	2.0	2.1	1.7	1.2	0.4	1.8	-1.0	0.5
Lung FVC	1.5	7.8	19.4	-2.1	3.7	2.2	4.4	3.6	-2.0	2.9	-1.0	1.2
Hearing difficulty/problems with background noise	1.5	2.3	8.2	-2.9	-1.7	-0.3	-0.9	-1.3	-2.5	1.0	-0.4	-0.2
Had menopause	1.5	1.9	7.1	-1.5	-0.9	0.4	-1.4	-0.3	-1.4	-0.7	-1.6	2.7
Pulse wave Arterial Stiffness index	1.5	1.7	3.7	0.3	-1.7	-1.6	-1.5	-1.9	-0.3	-1.8	0.6	0.5
Whole body fat mass	1.5	6.2	15.1	-0.2	-3.6	-2.7	-3.8	-3.9	-0.1	-2.6	0.1	0.1
Medication: Bendroflumethiazide	1.5	2.3	4.8	1.9	2.2	1.0	2.1	1.5	1.9	0.8	0.2	0.7
Hair/balding pattern: Pattern 3	1.4	2.1	4.7	1.4	1.8	1.2	1.8	0.8	1.4	2.2	1.2	0.5
Arm fat percentage (left)	1.4	5.6	12.2	-0.1	-3.4	-3.1	-3.5	-3.4	-0.1	-2.3	0.5	0.4
Wears glasses or contact lenses	1.4	1.6	4.0	-0.6	-1.9	-0.2	-1.7	-1.6	-0.3	-1.1	-0.3	2.0
Myopia	1.4	2.0	4.6	-2.1	-2.1	-0.5	-1.8	-1.6	-1.6	-0.9	0.2	-0.0
Fasting Glucose	1.3	1.5	2.8	1.2	1.7	0.4	1.5	1.4	1.1	1.4	0.9	-1.1
Medication: Atenolol	1.3	1.7	5.3	0.4	1.9	1.6	1.5	0.7	0.3	2.3	0.0	0.5
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	4.5	0.4	1.7	0.7	1.8	1.5	0.5	-1.1	0.7	-2.1
Lung cancer (father)	1.3	1.6	7.0	-1.1	-0.9	-0.7	-0.8	-1.1	-1.5	-0.3	-0.7	2.6
Exposure to tobacco smoke at home	1.3	1.5	3.7	1.8	0.4	0.4	0.9	0.7	1.9	1.2	1.8	-0.1
Hair/balding pattern: Pattern 4	1.3	3.0	4.7	-1.6	-1.7	-2.2	-1.7	-2.0	-1.8	-1.4	-1.7	-1.6
Mother’s age at death	1.3	1.6	5.0	0.3	-0.7	-1.9	-0.4	-0.7	0.5	0.3	2.1	-2.2
Supplements: Zinc	1.2	1.3	4.0	-2.0	-0.4	0.5	-0.1	-0.1	-1.8	-0.9	-1.6	-0.9
Medication: Co-codamol	1.2	1.4	2.4	-1.3	-1.3	-1.2	-1.6	-1.1	-1.3	-0.6	-1.2	0.1
Number of incorrect matches in round	1.2	1.9	7.7	-0.0	-0.2	1.3	-1.1	-0.5	-0.5	0.0	-2.5	2.8
Qualifications: None of the above	1.2	2.6	9.1	2.2	0.0	0.8	0.8	0.2	2.0	2.0	3.0	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	4.0	8.0	-1.2	2.5	2.8	2.7	2.0	-0.7	2.3	-1.3	1.2
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	5.5	-1.6	-2.4	-0.4	-1.5	-1.8	-1.7	-0.8	-0.9	-0.2
Medication: Blood pressure	1.2	2.1	5.6	1.5	2.4	-0.0	1.6	1.9	1.6	1.4	0.5	-0.1
Ever had prostate specific antigen (PSA) test	1.2	1.3	4.8	-0.3	-0.7	0.4	-1.1	-0.7	-0.2	-1.7	-1.3	2.2
Average weekly fortified wine intake	1.1	1.3	3.9	-2.0	-1.1	0.1	-0.6	-1.4	-1.7	-0.5	-0.9	-0.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.2	-0.8	-1.3	-1.4	-1.5	-1.5	-1.1	-1.3	-0.2	-0.1
Qualifications: CSEs or equivalent	1.1	1.4	4.8	1.8	-0.3	-2.2	0.2	-0.3	1.5	-0.5	1.4	-0.2
Nervous feelings	1.1	2.1	5.8	0.7	1.6	1.8	2.4	1.7	1.0	1.7	0.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.4	1.0	0.9	0.9	1.8	1.1	0.9	1.6	0.9	-0.4
Forced vital capacity (FVC), Best measure	1.1	4.0	8.0	-1.7	2.3	2.8	2.2	1.7	-1.4	2.2	-1.9	1.0
Medication: Omeprazole	1.1	1.3	4.5	-0.9	1.1	0.8	0.9	1.1	-1.2	1.0	0.3	-2.1
Commuting to job workplace: Car/motor vehicle	1.1	1.2	4.2	1.6	-0.4	-0.7	-0.3	0.5	1.4	0.1	1.2	2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	3.8	1.2	0.1	0.4	0.2	0.6	1.4	0.3	2.0	-1.7
Medication: Gliclazide	1.1	1.2	2.4	0.5	1.4	1.4	1.0	0.8	0.6	1.4	-0.7	-1.6
Age started oral contraceptive pill	1.1	1.4	2.7	-1.4	0.7	1.1	1.0	0.9	-1.6	0.9	1.1	-1.5
Cholesterol lowering medication	1.1	1.6	4.9	2.0	1.0	1.2	1.0	0.9	2.2	0.1	1.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.3	-0.7	-1.4	-1.3	-1.4	-1.4	-0.8	-1.8	-0.6	-0.3
Medication for hormone replacement therapy	1.0	1.1	5.7	0.2	-0.6	-1.7	-0.5	-0.4	-0.1	-2.4	0.6	0.3
Townsend deprivation index at recruitment	1.0	1.4	3.3	0.9	-1.2	-1.3	-1.2	-1.6	0.6	-1.8	0.6	-0.9
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.2	-0.8	-0.9	-0.8	-1.4	-1.4	-0.9	-1.2	-1.5	0.8
Trunk fat mass	1.0	4.5	11.6	0.2	-3.0	-2.1	-3.2	-3.4	0.3	-2.1	0.6	0.1
Medication: Cholesterol lowering	1.0	1.6	2.6	1.4	1.6	0.5	1.3	1.6	1.4	0.7	1.2	-1.0
Tense / ‘highly strung’	1.0	1.6	4.4	1.1	1.7	2.1	0.9	1.3	0.7	1.2	-1.3	0.8
Qualifications: nursing, teaching	1.0	1.5	3.0	-0.6	-1.5	-1.7	-1.7	-1.1	0.2	-1.6	-0.9	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	4.4	-0.6	1.1	0.7	0.8	1.1	-1.0	0.9	0.5	-2.1
Pack years of smoking	1.0	1.4	4.2	0.7	-1.4	-2.0	-1.8	-1.4	0.0	0.4	0.7	-0.7
Bipolar Disorder (2018)	0.9	1.5	3.0	-1.4	-1.4	-1.7	-1.4	-1.1	-1.3	-0.5	-0.3	-1.0
Angina	0.9	1.1	2.6	-0.1	0.8	0.1	1.4	1.6	0.4	1.3	1.5	-0.9
Diabetes (father)	0.9	1.1	2.7	1.6	1.4	-0.1	0.5	0.4	1.6	1.3	0.3	0.7
Hand grip strength (right)	0.9	2.6	5.6	-0.8	-2.0	-0.4	-2.4	-2.3	-0.7	-1.1	-2.2	1.0
Alcohol usually taken with meals	0.9	1.4	5.4	-0.8	1.7	1.1	1.1	1.2	-0.4	0.5	-0.1	-2.3
Father’s age at death	0.9	1.2	3.9	-1.1	-0.8	-0.5	-1.0	-2.0	-0.9	0.6	-1.0	-1.2
Neck or shoulder pain in last month	0.9	1.2	2.3	-0.7	-1.4	-0.7	-1.3	-0.7	-1.2	-1.3	-1.5	-0.6
Angina (self-reported)	0.9	1.2	2.8	-0.2	0.9	0.0	1.4	1.5	0.3	1.3	1.7	-1.1
Guilty feelings	0.9	1.3	3.0	-1.4	1.0	0.9	1.1	0.5	-1.7	1.5	-1.2	0.2
Pain experienced in last month	0.9	1.5	4.2	0.7	0.5	0.1	1.1	1.7	1.5	0.2	1.4	-2.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.3	0.7	1.5	1.0	1.0	1.5	0.5	0.8	-0.3	0.2
Pack years adult smoking proportion	0.8	1.2	4.3	1.0	-1.1	-2.1	-1.5	-1.2	0.3	0.3	0.7	-0.6
Current tobacco smoking	0.8	1.2	3.0	-0.8	-1.6	-1.5	-1.7	-0.7	-1.1	-0.7	-0.7	0.4
Serious illness, injury or assault to yourself	0.8	1.0	2.0	-0.6	1.4	0.7	1.2	1.4	-0.8	0.7	-0.5	-1.3
Sitting height	0.8	5.4	12.9	0.7	3.1	3.6	3.0	2.0	1.3	3.2	-0.2	-0.6
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	1.8	0.2	1.1	1.2	1.2	0.9	-0.1	1.2	-1.3	-0.8
Peak expiratory flow (PEF)	0.8	1.9	8.0	-1.6	-0.2	0.7	-0.0	-0.2	-1.1	-1.2	-1.8	2.8
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.8	-1.2	1.5	0.3	1.0	1.9	-0.7	-0.4	-1.3	-0.8
Glaucoma (self-reported)	0.8	1.0	3.1	0.1	1.3	0.4	1.0	0.7	-0.0	0.8	1.8	-1.3
Body fat percentage	0.8	3.2	6.9	0.6	-2.4	-2.2	-2.6	-2.5	0.6	-1.5	1.4	0.1
Number of children fathered	0.8	0.9	2.7	0.2	-0.8	-1.6	-0.2	-0.6	0.3	-0.5	1.7	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	4.5	-0.8	1.2	0.2	0.8	-0.1	-0.8	0.2	-0.5	-2.1
Shortness of breath walking on level ground	0.8	1.0	2.7	1.2	0.2	-0.6	0.9	0.9	1.0	0.1	1.4	-1.6
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.0	1.7	0.1	0.3	0.1	0.7	1.7	0.6	0.9	1.1
Emphysema/chronic bronchitis	0.8	0.9	3.3	-0.4	1.1	1.8	0.6	1.0	-0.4	0.4	-1.2	-0.6
Leg pain on walking	0.8	1.1	2.8	0.8	-0.9	-1.7	-0.8	-0.6	0.4	-0.5	1.5	-1.3
Loneliness, isolation	0.8	1.1	2.6	-0.9	-1.0	-0.2	-0.8	-1.1	-1.1	-1.6	-1.0	1.1
Smoking status: Current	0.8	1.3	2.5	-1.3	-1.6	-1.4	-1.4	-0.7	-1.4	-0.9	-0.6	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	4.3	-0.9	1.4	1.2	1.4	0.8	-0.7	2.1	0.3	1.9
Financial situation satisfaction	0.8	1.0	4.3	0.9	-0.4	-0.4	0.2	1.2	1.1	0.5	2.1	0.8
Eye problems/disorders: Glaucoma	0.8	1.0	2.3	0.4	1.2	0.3	1.1	0.3	0.3	1.4	1.5	-1.0
Alcohol drinker status: Never	0.8	0.9	1.8	-0.9	-0.7	-0.5	-1.2	-0.6	-1.4	-1.2	-1.1	-0.7
Ever smoked	0.8	1.3	3.7	-0.1	-1.9	-0.0	-1.9	-1.1	-0.0	-1.5	0.0	1.1
Irritability	0.8	1.3	4.2	0.5	1.5	2.0	1.0	0.9	-0.3	0.7	-1.3	0.9
Diastolic blood pressure, automated reading	0.8	2.4	6.2	0.3	2.5	1.3	2.2	2.3	0.2	2.0	0.1	0.2
Depressed Affect (Nagel 2018)	0.7	1.5	5.1	0.9	2.2	1.4	1.3	0.3	0.2	1.9	0.2	0.3
Reaction Time	0.7	1.3	3.1	-0.4	-1.0	-1.8	-0.9	-1.4	-0.5	-1.8	0.7	-0.5
Ovarian Cancer	0.7	0.9	2.8	1.7	0.0	0.8	-0.1	0.4	1.3	-0.3	0.4	1.7
Relative age of first facial hair	0.7	1.4	3.8	-1.9	-0.9	-0.2	-1.3	-0.9	-1.7	0.8	-0.3	-1.4
Maternal smoking around birth	0.7	0.9	4.0	1.4	0.2	-0.1	0.1	0.8	1.3	0.1	0.5	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.8	0.2	1.1	0.7	1.3	0.7	-0.2	1.9	0.8	0.0
Qualifications: A levels/AS levels or equivalent	0.7	1.5	6.9	-1.8	-0.4	-0.9	-0.8	-0.3	-1.3	-0.7	-2.6	0.3
Loud music exposure frequency	0.7	0.7	1.8	0.2	0.8	0.2	1.2	1.2	0.5	-0.1	1.4	-0.8
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	3.2	1.1	1.1	0.8	0.9	1.0	0.7	1.8	0.9	1.5
Illnesses of siblings: Diabetes	0.7	0.9	2.6	1.1	0.9	0.8	1.0	0.6	1.0	1.6	0.2	0.3
Friendships satisfaction	0.7	0.8	2.6	-1.6	-0.9	-0.3	-0.1	-0.3	-1.0	0.4	-0.4	-1.6
Back pain experienced in last month	0.7	1.0	3.4	0.2	1.1	1.3	0.9	0.5	-0.1	0.8	-0.9	1.9
Ever depressed for a whole week	0.7	0.9	2.0	0.1	1.2	1.1	0.9	1.4	-0.1	1.2	-0.8	0.4
Alcohol drinker status: Previous	0.7	0.8	2.6	0.5	1.6	-0.4	1.5	0.8	0.1	1.1	0.7	-0.0
Bipolar Disorder or Schizophrenia	0.6	1.4	4.6	-2.1	-0.9	-0.9	-1.1	-0.1	-1.7	0.6	-1.2	-0.7
Depression (Nagel 2018)	0.6	0.9	3.7	0.8	0.8	0.4	1.0	-0.2	0.5	1.9	1.3	0.5
Neuroticism (Nagel 2018)	0.6	1.5	4.5	0.3	1.7	2.1	0.8	-0.1	-0.4	1.7	-0.8	1.3
Alzheimer’s Disease (in father)	0.6	0.6	2.3	-1.5	-0.3	-0.5	-0.1	-0.5	-1.5	-0.3	-0.5	0.6
Primary Biliary Cirrhosis	0.6	0.9	2.5	0.4	1.6	1.2	1.5	1.2	0.2	0.5	-0.0	-0.1
Blood Red Count	0.6	5.8	12.5	-0.9	-3.4	-2.4	-3.0	-3.5	-0.5	-2.6	0.1	-2.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	3.9	-0.2	1.1	2.0	0.5	0.4	-0.7	-0.8	-1.0	0.1
Hair/balding pattern: Pattern 2	0.6	0.7	2.6	-0.6	-0.3	0.9	-0.6	-0.3	-0.8	-0.9	-1.0	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	5.6	-0.0	1.0	0.5	0.7	0.6	0.1	2.4	0.0	-0.8
Happiness	0.6	0.7	1.5	-1.1	-1.2	-1.2	-0.7	-0.6	-1.2	0.3	-0.2	-0.5
Noisy workplace	0.6	0.7	1.5	-0.4	-1.2	-0.5	-0.9	-0.9	-0.7	-0.7	1.0	0.9
High blood pressure (siblings)	0.6	0.9	2.9	-1.2	0.2	-0.5	-0.2	0.2	-1.3	1.7	-1.1	0.5
Eye problems/disorders: None of the above	0.6	0.7	2.6	0.9	-0.3	-1.1	-0.5	-0.2	0.9	-0.0	0.7	-1.6
Family relationship satisfaction	0.6	0.7	2.7	-0.5	-1.6	-0.6	-1.1	-1.1	-0.4	-0.2	-0.7	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.2	0.9	1.5	1.1	0.5	0.9	0.5	0.6	-0.4	0.8
Number of self-reported non-cancer illnesses	0.6	1.0	3.7	0.3	1.9	1.4	1.1	1.0	0.0	-0.8	-0.3	-0.4
Average weekly beer plus cider intake	0.6	0.9	2.0	-0.7	-0.9	-1.4	-0.9	-1.1	-1.1	-0.1	0.3	-1.1
Unable to work because of sickness or disability	0.6	0.8	2.3	1.5	0.1	0.7	-0.1	0.5	1.3	-1.0	-0.3	-0.9
Commuting to job workplace: Cycle	0.6	0.8	1.3	-0.9	-0.8	-1.0	-0.8	-0.8	-1.1	-0.4	-0.9	1.1
Supplements: Calcium	0.6	0.6	1.8	-1.4	0.2	0.7	0.4	0.6	-0.8	-0.4	-0.8	1.2
Waist Hip Ratio (WHR)	0.5	2.0	9.5	1.8	-0.5	-1.1	0.0	-0.3	1.9	0.3	3.1	0.7
Diabetes (mother)	0.5	0.6	2.1	0.6	0.7	-0.2	0.5	0.1	1.0	1.4	0.3	-1.0
Trunk fat percentage	0.5	2.2	4.2	0.9	-1.8	-1.4	-2.0	-2.1	1.0	-1.0	1.7	0.2
Financial difficulties in last 2 years	0.5	0.7	1.9	0.5	0.6	-0.4	0.6	1.1	0.5	0.7	1.4	-1.2
Mouth/teeth dental problems	0.5	0.8	2.0	-0.4	0.7	1.3	0.8	1.0	-0.2	-0.8	-1.4	-0.6
Pain all over the body in last month	0.5	0.5	2.1	0.7	-0.1	0.4	-1.1	-0.5	0.2	-0.5	-1.4	0.2
Mouth/teeth dental problems: Dentures	0.5	0.8	1.7	-0.0	-0.8	-0.8	-0.9	-1.2	-0.3	0.3	1.3	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.3	-0.8	-0.7	-0.9	-0.9	-0.7	-0.8	-1.2	-1.0	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.5	0.7	0.5	-0.2	0.6	0.5	0.7	1.1	1.2	1.1
Headache pain in last month	0.5	0.9	2.2	-0.9	-0.5	-1.5	-0.7	-1.4	-1.2	-0.1	0.9	-0.7
Birth weight	0.5	1.0	4.5	-1.4	0.3	0.1	-0.4	-0.3	-1.2	-0.3	-2.1	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.5	-0.2	-1.1	-0.6	-1.2	-1.1	-0.1	-1.1	-0.3	0.7
Medication for pain relief, constipation, heartburn	0.5	0.8	3.1	-0.9	-0.4	0.2	-0.8	-0.7	-0.5	0.0	-1.8	1.4
Mean time to correctly identify matches	0.5	1.0	3.0	0.2	-0.9	-0.9	-0.9	-1.2	0.0	-1.7	1.4	-0.2
Suffer from ‘nerves’	0.5	0.8	2.6	-0.5	1.2	-0.4	1.2	-0.1	-0.8	0.8	-0.4	-1.6
Age at last live birth	0.5	0.8	2.7	-0.7	-0.6	-0.8	0.1	-0.2	-0.7	-0.6	1.3	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.5	-1.1	-0.7	-0.9	-0.6	-1.4	-1.0	0.1	-1.9	0.9
Commuting to job workplace: Public transport	0.5	0.6	2.3	-1.5	0.4	0.4	0.2	0.3	-1.1	0.7	-0.4	-0.6
High cholesterol (Self-reported)	0.5	0.8	2.0	1.0	1.1	0.2	0.9	1.4	1.1	0.0	0.8	0.5
Risk taking	0.5	0.8	1.6	-1.3	-0.4	-0.7	-0.8	-0.2	-1.2	-1.0	-0.8	-0.8
Fractured/broken bones in last 5 years	0.5	0.7	3.0	0.6	0.5	-0.1	0.6	0.5	0.6	1.1	0.5	1.7
Basal cell carcinoma (self-reported)	0.5	0.6	1.7	-1.0	-0.3	-0.9	-0.3	0.0	-1.3	-1.1	-0.4	0.1
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.9	-1.0	1.7	1.2	1.3	1.4	-0.6	0.6	0.1	-0.6
Schizophrenia (2018)	0.4	0.9	2.5	-1.6	-0.1	0.2	-0.3	0.7	-1.1	1.2	-1.4	-0.1
Worry (Nagel 2018)	0.4	0.8	2.0	-0.6	0.8	1.3	0.4	-0.2	-0.9	1.1	-1.4	0.8
Alzheimer’s Disease (in mother)	0.4	0.5	2.6	0.8	0.7	0.4	0.1	0.3	0.8	0.0	-0.1	-1.6
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.2	-1.5	0.8	0.3	0.5	0.8	-1.3	-0.6	-1.3	-1.1
Blood Eosinophil Count	0.4	3.3	11.2	-1.5	-1.3	-0.0	-1.7	-1.9	-1.4	-2.5	-3.3	-0.2
Blood Platelet Count	0.4	4.8	12.6	1.8	0.1	-1.3	1.1	3.5	3.2	0.5	3.5	-1.2
Neuroticism	0.4	0.9	2.5	-0.8	0.7	0.5	0.0	-0.7	-1.5	1.2	-1.6	0.5
Number of treatments/medications taken	0.4	0.7	1.7	1.0	1.3	0.4	1.2	1.2	0.5	-0.8	-0.2	0.1
Hearing difficulty/problems: Yes	0.4	0.6	2.1	-0.6	-1.4	0.0	-0.8	-0.5	0.0	0.8	1.1	0.5
Ever had hysterectomy (womb removed)	0.4	0.5	1.3	0.7	-0.6	-0.3	-1.1	0.0	0.1	-1.1	0.4	0.7
Severe depression (siblings)	0.4	0.5	1.7	-0.1	-0.6	-1.3	-0.6	-0.7	-0.5	-0.9	-0.0	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	-0.5	-0.3	-0.5	-0.5	-0.5	-1.2	0.7	-0.8	-1.3
Had other major operations	0.4	0.5	2.0	-0.3	-0.3	-0.6	-0.7	-0.6	-0.1	-1.4	-0.4	-0.9
Medication: Ramipril	0.4	0.5	1.9	0.8	0.3	0.3	0.3	0.4	1.0	1.4	-0.3	0.3
Fluid intelligence score	0.4	0.9	1.6	-1.3	-0.4	-0.2	-0.8	-0.6	-1.2	-0.9	-1.0	-1.2
Worrier / anxious feelings	0.4	0.8	2.6	-0.8	0.7	1.1	0.1	-0.2	-1.2	0.8	-1.6	0.7
Number of live births	0.4	0.6	3.3	0.5	-0.2	0.2	0.2	0.3	0.7	0.3	1.0	-1.8
Age at first live birth	0.4	0.7	2.2	-0.6	-0.8	-0.7	-0.0	-0.6	-0.6	-1.5	0.9	-1.1
Health satisfaction	0.4	0.5	1.5	-0.8	-0.1	-1.1	0.3	1.2	-0.6	0.4	-0.5	-0.8
Migraine (self-reported)	0.4	0.5	2.0	-0.9	0.3	-1.4	0.1	-0.3	-1.2	-0.2	-0.5	-0.0
Medication: Seretide 50 evohaler	0.4	0.4	1.6	0.0	0.8	0.5	0.9	1.2	-0.0	0.3	0.1	-0.7
Number of full sisters	0.4	0.5	1.7	0.8	-0.6	-1.3	-0.4	-0.4	0.6	0.4	0.8	-0.3
Mood swings	0.4	0.7	2.2	0.9	1.5	0.1	0.6	0.2	0.0	1.4	-0.0	-0.9
Commuting to job workplace: Walk	0.4	0.4	1.6	-0.4	0.9	1.3	0.5	-0.3	-0.3	0.1	-0.6	-0.7
Average weekly champagne plus white wine intake	0.4	0.6	1.6	0.6	-0.9	-0.3	-1.3	-0.7	0.7	-0.9	-0.0	-0.8
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.3	-0.7	0.2	0.9	0.3	0.1	-0.7	0.7	0.2	-1.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.9	-0.2	-0.6	-0.4	-0.9	-0.8	-0.7	-0.9	-1.0	-0.1
Heart disease (siblings)	0.4	0.5	2.3	0.9	-0.1	-0.9	-0.0	0.2	0.4	-0.2	1.5	0.4
Neuroticism (2016)	0.3	0.5	2.3	-0.9	0.7	-0.1	0.2	0.1	-1.5	0.4	-0.4	-0.7
Schizophrenia (2014)	0.3	0.6	2.0	-1.2	-0.6	-0.5	-0.8	-0.0	-0.8	0.1	-1.4	-0.6
Hypothyroidism (self reported)	0.3	0.8	2.1	0.4	0.6	-0.3	0.8	1.0	0.1	1.4	1.1	1.3
Respiratory disease	0.3	0.8	4.1	0.2	0.3	-0.2	0.3	0.2	0.3	-2.0	-0.4	-1.5
Chronotype (morning person)	0.3	0.6	2.0	0.1	-0.9	-0.2	-0.6	0.0	0.8	-1.4	-0.7	1.1
Tanning	0.3	3.6	6.5	1.9	2.0	-0.6	2.5	1.5	1.8	1.9	2.4	-1.6
Hand grip strength (left)	0.3	0.7	2.3	0.4	-0.6	0.0	-0.8	-1.1	0.0	-1.1	-1.5	0.7
Sensitivity / hurt feelings	0.3	0.5	1.8	0.7	-0.2	-0.3	-0.3	-1.3	0.1	-1.0	-0.0	0.8
Taking other prescription medications	0.3	0.4	1.5	0.5	0.4	0.7	-0.1	0.1	-0.2	-1.2	-0.2	-1.2
Age when periods started (menarche)	0.3	0.6	4.3	-0.5	0.3	0.3	0.4	-0.2	-0.9	-0.2	-0.0	-2.1
Chronic bronchitis/emphysema (father)	0.3	0.3	1.0	-0.3	-0.2	-0.2	-0.6	-1.0	-0.4	-0.4	-0.8	0.3
Past tobacco smoking	0.3	0.6	1.6	-0.4	0.8	-0.5	0.6	0.1	-0.5	1.1	-0.8	-1.3
Diabetes (self-reported)	0.3	0.4	1.4	0.8	0.9	-0.1	0.5	0.1	0.4	0.4	-0.7	-1.2
Illnesses of siblings	0.3	0.4	1.1	0.7	0.1	0.7	0.3	0.2	1.1	-1.0	0.3	0.3
Neuroticism score	0.3	0.7	2.1	-0.5	0.6	0.6	0.4	-0.5	-1.3	0.8	-1.5	0.3
Asthma	0.3	0.6	1.1	0.8	0.6	-0.9	1.1	0.8	0.6	-0.9	0.5	-0.5
Prospective memory result	0.3	0.3	1.5	0.4	0.5	1.2	-0.2	-0.0	0.3	-0.3	-0.9	0.2
Medication: Paracetamol	0.3	0.5	1.6	1.3	-0.1	-0.1	-0.1	-0.2	1.0	-0.7	0.8	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.6	0.6	0.4	-0.8	0.4	0.0	-0.2	-0.8	0.6	-0.8
Medication: Allopurinol	0.3	0.4	1.4	0.6	0.6	1.2	0.5	0.3	0.8	-0.2	-0.1	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.3	0.1	-0.4	0.3	-1.2	-0.5	-0.0	-1.1	-0.1	0.2
Illnesses of father: Heart disease	0.3	0.5	2.3	-0.4	0.1	-0.5	0.4	0.7	-0.4	1.5	0.3	-0.8
Smoking status: Previous	0.3	0.4	1.7	0.5	-0.5	0.4	-0.5	-0.0	0.5	-1.3	0.8	0.8
Average weekly red wine intake	0.3	0.4	1.3	-1.1	0.2	-1.2	0.2	-0.7	-0.8	-0.2	-0.2	-0.3
Long-standing illness, disability or infirmity	0.3	0.4	2.0	0.9	-0.0	0.4	-0.1	-0.2	0.8	-1.4	0.3	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.2	-0.4	0.1	-0.4	-0.3	-1.1	-0.6	0.1	-0.9	1.1
Smoking Status	0.2	0.4	1.2	-0.8	-0.7	-0.7	-0.8	-0.1	-1.1	-0.3	-0.4	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.8	0.1	0.4	-0.4	0.2	-0.2	-0.0	0.3	-0.7	-1.7
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.0	0.0	-0.4	-1.0	-0.2	-0.7	-0.1	0.1	0.7	-0.6
Medication: Metformin	0.2	0.3	2.1	0.4	0.1	-0.3	0.3	-0.4	0.3	-0.1	0.5	-1.5
Relative age voice broke	0.2	0.4	0.8	-0.9	-0.4	0.2	-0.6	-0.7	-0.7	0.7	-0.3	0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	-0.7	-0.1	-0.1	-0.0	0.3	-0.8	0.1	-0.3	0.4
Stomach or abdominal pain in last month	0.2	0.2	0.7	-0.2	0.1	0.1	0.3	-0.7	-0.3	0.7	0.8	-0.4
Medication: Simvastatin	0.2	0.3	1.0	0.1	1.0	-0.0	0.7	0.9	0.1	0.3	0.2	-0.7
Falls in the last year	0.2	0.3	0.6	-0.6	-0.7	-0.7	-0.1	0.0	-0.2	0.8	0.4	0.8
Depression (self-reported)	0.2	0.3	1.1	0.0	0.6	0.3	0.1	0.4	-0.2	0.6	-0.7	-1.1
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.1	-0.1	-0.1	-0.5	0.1	0.4	-0.5	0.5	-0.0	-1.0
Gout (self-reported)	0.2	0.2	0.7	0.7	0.0	0.3	0.1	-0.6	0.8	-0.6	0.4	-0.1
Worry too long after embarrassment	0.2	0.4	1.1	-0.8	-0.7	-0.0	-0.6	0.0	-1.0	0.6	-0.8	0.2
Wheeze or whistling in the chest in last year	0.2	0.4	1.6	0.2	-0.5	-0.5	-0.3	-0.8	-0.3	-1.3	-0.2	-0.4
Pulse rate, automated reading	0.2	0.8	1.6	-0.9	-0.7	-0.7	-0.7	-0.5	-1.0	-1.3	-1.2	-0.5
Comparative height size at age 10	0.2	1.1	4.2	0.8	1.1	2.0	0.5	0.1	0.5	1.2	-0.2	1.1
Overall health rating	0.2	0.4	0.9	-0.6	-0.5	-0.3	-1.0	-0.6	-0.9	-0.0	-0.9	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	-0.3	0.0	0.2	0.1	0.5	-0.2	-0.6	-0.8	-0.6
Diabetes diagnosed by doctor	0.2	0.3	1.1	0.9	0.6	-0.5	0.2	-0.1	0.5	0.1	-0.5	-1.0
Asthma (self-reported)	0.2	0.5	0.9	0.8	0.5	-0.7	1.0	0.7	0.6	-0.8	0.4	-0.7
Ever taken oral contraceptive pill	0.2	0.3	0.7	-0.2	0.3	0.6	0.8	0.7	0.1	0.3	0.8	-0.0
Medication: Paracetamol	0.2	0.3	0.8	0.4	-0.3	-0.7	-0.1	-0.0	0.3	-0.9	0.5	-0.7
Alzheimer’s Disease (including proxy)	0.1	0.1	0.9	-0.1	-0.0	0.1	-0.3	-0.2	-0.1	-0.1	-0.4	-0.9
Breast Cancer	0.1	0.2	1.0	0.2	-0.0	0.7	-0.1	-1.0	0.1	0.6	0.0	-0.2
Ulcerative Colitis	0.1	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9
Blood White Count	0.1	0.6	1.6	0.4	-0.9	-0.2	-0.6	-1.0	0.4	1.3	1.2	0.3
Heel T-Score	0.1	0.7	1.8	-0.5	-1.0	0.2	-0.8	-0.7	-0.5	-0.1	-1.4	1.3
Height	0.1	2.6	9.2	0.2	-1.1	1.6	-1.4	-2.0	0.6	-2.1	0.3	-3.0
Lung FEV1/FVC ratio	0.1	0.5	2.5	-0.3	0.7	0.5	1.0	1.6	-0.2	0.4	0.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.6	-0.3	-0.7	-0.3	-0.5	-0.8	-0.0	0.1	-0.2	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.3	-0.1	-0.6	-0.5	-0.4	-0.5	-0.0	0.3	0.2	-0.1
Time employed in main current job	0.1	0.1	0.3	-0.5	-0.2	-0.5	0.4	-0.2	-0.5	-0.1	-0.2	0.0
Pulse rate	0.1	0.2	0.7	-0.5	-0.2	-0.6	-0.1	0.1	-0.8	-0.9	-0.0	0.0
Standing height	0.1	0.8	5.7	0.2	0.2	2.4	-0.0	-0.6	0.7	0.0	-0.7	-0.5
Alcohol intake frequency.	0.1	0.3	0.8	0.4	-0.3	-0.8	-0.3	-0.2	-0.1	0.2	0.9	-0.9
Illnesses of father: None of the above (group 1)	0.1	0.1	0.6	-0.2	-0.1	0.3	-0.1	0.0	-0.3	-0.8	-0.2	0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2
HbA1C	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3
HDL Cholesterol	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.5
LDL Cholesterol	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.6
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.2	0.5	-0.2	0.3	-0.7	0.7	-0.2	-0.2	-0.4	0.7	0.3

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