Best TWAS P=5.02e-08 · Best GWAS P=1.85e-07 conditioned to 0.00383
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | SNHG5 | 0.29 | 0.34 | lasso | 3 | 0.34 | 7.3e-13 | 4.4 | -5.5 | 5.0e-08 | 0.50 | 0.18 | 0.77 | TRUE |
| 2 | GTEx | Liver | SNHG5 | 0.47 | 0.42 | enet | 25 | 0.52 | 1.0e-16 | 4.4 | -5.2 | 2.4e-07 | 0.34 | 0.12 | 0.85 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SYNCRIP | 0.07 | 0.04 | blup | 35 | 0.03 | 1.3e-02 | 4.5 | 5.3 | 1.3e-07 | -0.33 | 0.02 | 0.65 | FALSE |